Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25910 (3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6 | -46.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25913 (3-(4-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6.5 | -46.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25909 (3-(3-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 9.90 | -45.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25912 (3-(3-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 10.1 | -45.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25916 (3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 11.5 | -45.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25907 (2-(hydrazinecarbonyl)-3-(4-methylphenyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 12.2 | -45.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25908 (3-(2-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 12.5 | -45.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25906 (2-(hydrazinecarbonyl)-3-(3-methylphenyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 13.3 | -45.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25915 (3-(3-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 13.4 | -44.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 35 | -42.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM10882 (6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 40 | -42.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25914 (3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 260 | -37.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25918 (2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 260 | -37.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25905 (2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 326 | -37.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25917 (2-(hydrazinecarbonyl)-3-(3-methoxyphenyl)-1H-indol...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 330 | -37.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25904 (2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfona...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 339 | -36.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-carbonic anhydrase domain-containing protein (Caenorhabditis elegans) | BDBM25911 (3-(2-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 372 | -36.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Istanbul University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... | Bioorg Med Chem 17: 3212-5 (2009) Article DOI: 10.1016/j.bmc.2009.01.048 BindingDB Entry DOI: 10.7270/Q2MS3R3Q | |||||||||||
More data for this Ligand-Target Pair |