Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent T-type calcium channel subunit alpha-1H (Rattus norvegicus) | BDBM50452245 (Act-709478) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Idorsia Pharmaceuticals Ltd. Curated by ChEMBL | Assay Description Inhibition of Cav3.2 in rat assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assa... | J Med Chem 60: 9769-9789 (2017) Article DOI: 10.1021/acs.jmedchem.7b01236 BindingDB Entry DOI: 10.7270/Q24M9745 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent T-type calcium channel subunit alpha-1H (Rattus norvegicus) | BDBM50095309 (CHEMBL3589557) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie, Inc. Curated by ChEMBL | Assay Description Inhibition of Cav3.2 channel in rat DRG neurons assessed as reduction in LVA currents | ACS Med Chem Lett 6: 641-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00023 BindingDB Entry DOI: 10.7270/Q27D2WW3 | |||||||||||
More data for this Ligand-Target Pair |