Found 7 hits of affinity data for UniProtKB/TrEMBL: P29319 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ephrin type-A receptor 3
(Mus musculus) | BDBM50468261
(Tyrphostin Ag 879 | Tyrphostin Ag-879)Show SMILES CC(C)(C)c1cc(\C=C(/C#N)C(N)=S)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,21H,1-6H3,(H2,20,22)/b12-7+ | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
PAK Research Center
Curated by ChEMBL
| Assay Description
Inhibition of ETK phosphorylation in mouse RAS-3T3 cells incubated for 1 hr by immunoblot |
Eur J Med Chem 142: 229-243 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.043
BindingDB Entry DOI: 10.7270/Q21J9DG3 |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 3
(Mus musculus) | BDBM50384721
(CHEMBL2037224)Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2cccc(Nc3ccc4\C(=C\c5ccc[nH]5)C(=O)Nc4c3)c2)c1 Show InChI InChI=1S/C27H20F3N5O2/c28-27(29,30)16-4-1-5-18(12-16)33-26(37)34-20-7-2-6-19(13-20)32-21-9-10-22-23(14-17-8-3-11-31-17)25(36)35-24(22)15-21/h1-15,31-32H,(H,35,36)(H2,33,34,37)/b23-14- | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Tel-fused EPHA3 in mouse BA/F3 cells |
ACS Med Chem Lett 3: 140-145 (2012)
Article DOI: 10.1021/ml200261d
BindingDB Entry DOI: 10.7270/Q2SJ1MNM |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 3
(Mus musculus) | BDBM50551201
(CHEMBL4761556)Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)NCC)[C@H](C)CCC(=O)N[C@H](CC(O)=O)Cc1c[nH]c2ccccc12 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of biotinylated ephrin-A1-Fc from mouse EphA3 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112083
BindingDB Entry DOI: 10.7270/Q2X35233 |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 3
(Mus musculus) | BDBM50384725
(CHEMBL2037209)Show SMILES Cc1cn(cn1)-c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1 Show InChI InChI=1S/C31H23F3N6O2/c1-18-16-40(17-36-18)25-11-19(10-20(12-25)31(32,33)34)29(41)38-23-5-2-4-22(13-23)37-24-7-8-26-27(14-21-6-3-9-35-21)30(42)39-28(26)15-24/h2-17,35,37H,1H3,(H,38,41)(H,39,42)/b27-14- | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Tel-fused EPHA3 in mouse BA/F3 cells |
ACS Med Chem Lett 3: 140-145 (2012)
Article DOI: 10.1021/ml200261d
BindingDB Entry DOI: 10.7270/Q2SJ1MNM |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 3
(Mus musculus) | BDBM50384726
(CHEMBL2037208)Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1 Show InChI InChI=1S/C27H19F3N4O2/c28-27(29,30)17-5-1-4-16(12-17)25(35)33-20-7-2-6-19(13-20)32-21-9-10-22-23(14-18-8-3-11-31-18)26(36)34-24(22)15-21/h1-15,31-32H,(H,33,35)(H,34,36)/b23-14- | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Tel-fused EPHA3 in mouse BA/F3 cells |
ACS Med Chem Lett 3: 140-145 (2012)
Article DOI: 10.1021/ml200261d
BindingDB Entry DOI: 10.7270/Q2SJ1MNM |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 3
(Mus musculus) | BDBM50384720
(CHEMBL2037220)Show SMILES CN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4cc(c[nH]4)C(O)=O)C(=O)Nc3c2)c1 Show InChI InChI=1S/C33H29F3N6O4/c1-41-7-9-42(10-8-41)26-13-19(11-21(14-26)33(34,35)36)30(43)39-23-4-2-3-22(15-23)38-24-5-6-27-28(31(44)40-29(27)17-24)16-25-12-20(18-37-25)32(45)46/h2-6,11-18,37-38H,7-10H2,1H3,(H,39,43)(H,40,44)(H,45,46)/b28-16- | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Tel-fused EPHA3 in mouse BA/F3 cells |
ACS Med Chem Lett 3: 140-145 (2012)
Article DOI: 10.1021/ml200261d
BindingDB Entry DOI: 10.7270/Q2SJ1MNM |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 3
(Mus musculus) | BDBM50384727
(CHEMBL2037226)Show SMILES Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30,31)32)5-9-22(25)29)13-23(15)34-18-7-8-20-21(12-17-3-2-10-33-17)26(38)36-24(20)14-18/h2-14,33-34H,1H3,(H,36,38)(H2,35,37,39)/b21-12- | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Tel-fused EPHA3 in mouse BA/F3 cells |
ACS Med Chem Lett 3: 140-145 (2012)
Article DOI: 10.1021/ml200261d
BindingDB Entry DOI: 10.7270/Q2SJ1MNM |
More data for this
Ligand-Target Pair | |
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