Found 30 hits of affinity data for UniProtKB/TrEMBL: Q2KHZ8 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50329782
((5R,6R,7S,8R,8aS)-3-(octylimino)hexahydro-1H-thiaz...)Show SMILES CCCCCCCC\N=C1/SC[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)N12 |r| Show InChI InChI=1S/C15H28N2O4S/c1-2-3-4-5-6-7-8-16-15-17-10(9-22-15)11(18)12(19)13(20)14(17)21/h10-14,18-21H,2-9H2,1H3/b16-15-/t10-,11-,12+,13-,14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase after 10 to 30 mins |
Bioorg Med Chem 18: 7439-45 (2010)
Article DOI: 10.1016/j.bmc.2010.09.003
BindingDB Entry DOI: 10.7270/Q2JS9QPK |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101405
(CHEMBL3393931)Show SMILES [H][C@]12OC(SCCCCCCCCCCCCCCCCO)=N[C@@]1([H])O[C@H](CO)[C@H](O)[C@@H]2O |r,c:21| Show InChI InChI=1S/C23H43NO6S/c25-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-31-23-24-22-21(30-23)20(28)19(27)18(17-26)29-22/h18-22,25-28H,1-17H2/t18-,19+,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.3 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101398
(CHEMBL3393930)Show SMILES [H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])OC(SCCCCCCCCCCCCCCCCF)=N2 |r,c:32| Show InChI InChI=1S/C23H42FNO5S/c24-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-31-23-25-22-21(30-23)20(28)19(27)18(17-26)29-22/h18-22,26-28H,1-17H2/t18-,19-,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.3 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101399
(CHEMBL3393929)Show SMILES [H][C@]12OC(SCCCCCCCCCCCCCCCCSC3=N[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@]4([H])O3)=N[C@@]1([H])O[C@H](CO)[C@@H](O)[C@@H]2O |r,c:38,t:22| Show InChI InChI=1S/C30H52N2O10S2/c33-17-19-21(35)23(37)25-27(39-19)31-29(41-25)43-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-44-30-32-28-26(42-30)24(38)22(36)20(18-34)40-28/h19-28,33-38H,1-18H2/t19-,20-,21-,22-,23+,24+,25-,26-,27+,28+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.3 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101401
(CHEMBL3393928)Show SMILES [H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])OC(SCCCCCCCCCCCCCCCCI)=N2 |r,c:32| Show InChI InChI=1S/C23H42INO5S/c24-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-31-23-25-22-21(30-23)20(28)19(27)18(17-26)29-22/h18-22,26-28H,1-17H2/t18-,19-,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.3 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101403
(CHEMBL3393932)Show SMILES [H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])OC(SCCCCCCCCCCCCCCCC(O)=O)=N2 |r,c:33| Show InChI InChI=1S/C23H41NO7S/c25-16-17-19(28)20(29)21-22(30-17)24-23(31-21)32-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-18(26)27/h17,19-22,25,28-29H,1-16H2,(H,26,27)/t17-,19-,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.3 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50329779
(5-N,6-S-[N'-(4-Dapoxylsulfonylamino)butyliminometh...)Show SMILES CN(C)c1ccc(cc1)-c1cnc(o1)-c1cccc(c1)S(=O)(=O)NCCCC\N=C1/SC[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)N12 |r| Show InChI InChI=1S/C28H35N5O7S2/c1-32(2)19-10-8-17(9-11-19)22-15-30-26(40-22)18-6-5-7-20(14-18)42(38,39)31-13-4-3-12-29-28-33-21(16-41-28)23(34)24(35)25(36)27(33)37/h5-11,14-15,21,23-25,27,31,34-37H,3-4,12-13,16H2,1-2H3/b29-28-/t21-,23-,24+,25-,27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase after 10 to 30 mins |
Bioorg Med Chem 18: 7439-45 (2010)
Article DOI: 10.1016/j.bmc.2010.09.003
BindingDB Entry DOI: 10.7270/Q2JS9QPK |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101402
(CHEMBL3393927)Show SMILES [H][C@]12OC(SCCCCCCCCCCCCCCCC(=O)OC)=N[C@@]1([H])O[C@H](CO)[C@@H](O)[C@@H]2O |r,c:23| Show InChI InChI=1S/C24H43NO7S/c1-30-19(27)15-13-11-9-7-5-3-2-4-6-8-10-12-14-16-33-24-25-23-22(32-24)21(29)20(28)18(17-26)31-23/h18,20-23,26,28-29H,2-17H2,1H3/t18-,20-,21+,22-,23+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.3 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 7.3 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50329783
(5-N,6-S-[N'-(4-Dansylamino)butyliminomethylidene]-...)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCC\N=C1/SC[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)N12 |r| Show InChI InChI=1S/C23H32N4O6S2/c1-26(2)16-9-5-8-15-14(16)7-6-10-18(15)35(32,33)25-12-4-3-11-24-23-27-17(13-34-23)19(28)20(29)21(30)22(27)31/h5-10,17,19-22,25,28-31H,3-4,11-13H2,1-2H3/b24-23-/t17-,19-,20+,21-,22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase after 10 to 30 mins |
Bioorg Med Chem 18: 7439-45 (2010)
Article DOI: 10.1016/j.bmc.2010.09.003
BindingDB Entry DOI: 10.7270/Q2JS9QPK |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50329781
(5-N,6-S-[N'-[4-(7'-Diethylaminocoumarin-30-ylcarbo...)Show SMILES CCN(CC)c1ccc2cc(c(=O)oc2c1)S(=O)(=O)NCCCC\N=C1/SC[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)N12 |r| Show InChI InChI=1S/C24H34N4O8S2/c1-3-27(4-2)15-8-7-14-11-18(23(33)36-17(14)12-15)38(34,35)26-10-6-5-9-25-24-28-16(13-37-24)19(29)20(30)21(31)22(28)32/h7-8,11-12,16,19-22,26,29-32H,3-6,9-10,13H2,1-2H3/b25-24-/t16-,19-,20+,21-,22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase after 10 to 30 mins |
Bioorg Med Chem 18: 7439-45 (2010)
Article DOI: 10.1016/j.bmc.2010.09.003
BindingDB Entry DOI: 10.7270/Q2JS9QPK |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50329780
(5-N,6-S-[N'-[4-(6-Dansylaminohexanamido)butyl]imin...)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCS(=O)(=O)NCCCC\N=C1/SC[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)N12 |r| Show InChI InChI=1S/C28H43N5O8S3/c1-32(2)21-12-8-11-20-19(21)10-9-13-23(20)44(40,41)31-16-4-3-7-17-43(38,39)30-15-6-5-14-29-28-33-22(18-42-28)24(34)25(35)26(36)27(33)37/h8-13,22,24-27,30-31,34-37H,3-7,14-18H2,1-2H3/b29-28-/t22-,24-,25+,26-,27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Sevilla
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase after 10 to 30 mins |
Bioorg Med Chem 18: 7439-45 (2010)
Article DOI: 10.1016/j.bmc.2010.09.003
BindingDB Entry DOI: 10.7270/Q2JS9QPK |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101402
(CHEMBL3393927)Show SMILES [H][C@]12OC(SCCCCCCCCCCCCCCCC(=O)OC)=N[C@@]1([H])O[C@H](CO)[C@@H](O)[C@@H]2O |r,c:23| Show InChI InChI=1S/C24H43NO7S/c1-30-19(27)15-13-11-9-7-5-3-2-4-6-8-10-12-14-16-33-24-25-23-22(32-24)21(29)20(28)18(17-26)31-23/h18,20-23,26,28-29H,2-17H2,1H3/t18-,20-,21+,22-,23+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101403
(CHEMBL3393932)Show SMILES [H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])OC(SCCCCCCCCCCCCCCCC(O)=O)=N2 |r,c:33| Show InChI InChI=1S/C23H41NO7S/c25-16-17-19(28)20(29)21-22(30-17)24-23(31-21)32-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-18(26)27/h17,19-22,25,28-29H,1-16H2,(H,26,27)/t17-,19-,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101405
(CHEMBL3393931)Show SMILES [H][C@]12OC(SCCCCCCCCCCCCCCCCO)=N[C@@]1([H])O[C@H](CO)[C@H](O)[C@@H]2O |r,c:21| Show InChI InChI=1S/C23H43NO6S/c25-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-31-23-24-22-21(30-23)20(28)19(27)18(17-26)29-22/h18-22,25-28H,1-17H2/t18-,19+,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101398
(CHEMBL3393930)Show SMILES [H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])OC(SCCCCCCCCCCCCCCCCF)=N2 |r,c:32| Show InChI InChI=1S/C23H42FNO5S/c24-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-31-23-25-22-21(30-23)20(28)19(27)18(17-26)29-22/h18-22,26-28H,1-17H2/t18-,19-,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101401
(CHEMBL3393928)Show SMILES [H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])OC(SCCCCCCCCCCCCCCCCI)=N2 |r,c:32| Show InChI InChI=1S/C23H42INO5S/c24-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-31-23-25-22-21(30-23)20(28)19(27)18(17-26)29-22/h18-22,26-28H,1-17H2/t18-,19-,20+,21-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50101399
(CHEMBL3393929)Show SMILES [H][C@]12OC(SCCCCCCCCCCCCCCCCSC3=N[C@@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@]4([H])O3)=N[C@@]1([H])O[C@H](CO)[C@@H](O)[C@@H]2O |r,c:38,t:22| Show InChI InChI=1S/C30H52N2O10S2/c33-17-19-21(35)23(37)25-27(39-19)31-29(41-25)43-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-44-30-32-28-26(42-30)24(38)22(36)20(18-34)40-28/h19-28,33-38H,1-18H2/t19-,20-,21-,22-,23+,24+,25-,26-,27+,28+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
Universitat Rovira i Virgili
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase at pH 5.5 incubated for 10 to 30 mins using beta-D-glycopyranoside substrate by spectrophotometry |
Eur J Med Chem 90: 258-66 (2015)
Article DOI: 10.1016/j.ejmech.2014.11.002
BindingDB Entry DOI: 10.7270/Q2H996ZT |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)Show InChI InChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5+,6-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... |
Bioorg Med Chem 19: 3558-68 (2011)
Article DOI: 10.1016/j.bmc.2011.04.011
BindingDB Entry DOI: 10.7270/Q2BC3ZWW |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50182801
((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)Show InChI InChI=1S/C6H13NO3/c8-3-4-1-7-2-5(9)6(4)10/h4-10H,1-3H2/t4-,5-,6-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... |
Bioorg Med Chem 19: 3558-68 (2011)
Article DOI: 10.1016/j.bmc.2011.04.011
BindingDB Entry DOI: 10.7270/Q2BC3ZWW |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50350758
(CHEMBL1818433)Show InChI InChI=1S/C6H13NO3/c8-3-4-1-7-2-5(9)6(4)10/h4-10H,1-3H2/t4-,5-,6+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... |
Bioorg Med Chem 19: 3558-68 (2011)
Article DOI: 10.1016/j.bmc.2011.04.011
BindingDB Entry DOI: 10.7270/Q2BC3ZWW |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM18361
((2R,3S,4R,5R,6R)-2-butyl-6-(hydroxymethyl)piperidi...)Show SMILES CCCC[C@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O Show InChI InChI=1S/C10H21NO4/c1-2-3-4-6-8(13)10(15)9(14)7(5-12)11-6/h6-15H,2-5H2,1H3/t6-,7-,8+,9-,10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase |
J Med Chem 55: 10347-62 (2012)
Article DOI: 10.1021/jm301304e
BindingDB Entry DOI: 10.7270/Q2K35VTX |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM18351
((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase |
J Med Chem 55: 10347-62 (2012)
Article DOI: 10.1021/jm301304e
BindingDB Entry DOI: 10.7270/Q2K35VTX |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50360268
(CHEMBL1933098)Show InChI InChI=1S/C7H15NO3/c1-4-2-8-3-5(9)7(11)6(4)10/h4-11H,2-3H2,1H3/t4-,5-,6-,7-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.44E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR CNRS 7201
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase |
Bioorg Med Chem 20: 641-9 (2012)
Article DOI: 10.1016/j.bmc.2010.09.053
BindingDB Entry DOI: 10.7270/Q2GB24HJ |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50240725
((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...)Show InChI InChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5-,6-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... |
Bioorg Med Chem 19: 3558-68 (2011)
Article DOI: 10.1016/j.bmc.2011.04.011
BindingDB Entry DOI: 10.7270/Q2BC3ZWW |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50360270
(CHEMBL1933096)Show InChI InChI=1S/C7H15NO4/c9-3-4-1-8-2-5(10)7(12)6(4)11/h4-12H,1-3H2/t4-,5+,6+,7+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.32E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR CNRS 7201
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase |
Bioorg Med Chem 20: 641-9 (2012)
Article DOI: 10.1016/j.bmc.2010.09.053
BindingDB Entry DOI: 10.7270/Q2GB24HJ |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50360271
(CHEMBL1933095)Show InChI InChI=1S/C7H15NO4/c9-3-4-1-8-2-5(10)7(12)6(4)11/h4-12H,1-3H2/t4-,5-,6-,7-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.47E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR CNRS 7201
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase |
Bioorg Med Chem 20: 641-9 (2012)
Article DOI: 10.1016/j.bmc.2010.09.053
BindingDB Entry DOI: 10.7270/Q2GB24HJ |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50437451
(CHEMBL2409348)Show SMILES CC[C@@H]1NC[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(10)3-9-4/h4-13H,2-3H2,1H3/t4-,5+,6-,7+,8+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.87E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Poitiers
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase |
Bioorg Med Chem 21: 4803-12 (2013)
Article DOI: 10.1016/j.bmc.2013.03.035
BindingDB Entry DOI: 10.7270/Q2GQ7053 |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50263043
(CHEMBL501385 | L-Isofagomine)Show InChI InChI=1S/C6H13NO3/c8-3-4-1-7-2-5(9)6(4)10/h4-10H,1-3H2/t4-,5-,6-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.11E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... |
Bioorg Med Chem 19: 3558-68 (2011)
Article DOI: 10.1016/j.bmc.2011.04.011
BindingDB Entry DOI: 10.7270/Q2BC3ZWW |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50350757
(CHEMBL1818432)Show InChI InChI=1S/C6H13NO3/c8-3-4-1-7-2-5(9)6(4)10/h4-10H,1-3H2/t4-,5+,6+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... |
Bioorg Med Chem 19: 3558-68 (2011)
Article DOI: 10.1016/j.bmc.2011.04.011
BindingDB Entry DOI: 10.7270/Q2BC3ZWW |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Bos taurus) | BDBM50437444
(CHEMBL2409320)Show InChI InChI=1S/C5H11NO3/c7-2-4(9)5-3(8)1-6-5/h3-9H,1-2H2/t3-,4-,5+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.97E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of bovine liver beta-glucosidase |
Bioorg Med Chem 21: 4813-9 (2013)
Article DOI: 10.1016/j.bmc.2013.03.004
BindingDB Entry DOI: 10.7270/Q2MG7QXG |
More data for this
Ligand-Target Pair | |
Search and Browse
