Compile Data Set for Download or QSAR

Found 395 hits for UniProtKB: P19156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM50001247 (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) Show SMILES CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C Show InChI InChI=1S/C20H20N2O3/c1-4-25-20(23)15-12-21-19-14(9-7-11-17(19)24-3)18(15)22-16-10-6-5-8-13(16)2/h5-12H,4H2,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Research Ltd. Curated by ChEMBL					Assay Description Binding affinity of compound towards H+/K+ ATPase for activation was determined				J Med Chem 33: 527-33 (1990) BindingDB Entry DOI: 10.7270/Q2Z31XND
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM50013228 (6-Methoxy-4-methyl-1-o-tolyl-2,3-dihydro-1H-pyrrol...) Show SMILES COc1cccc2c3N(CCc3c(C)nc12)c1ccccc1C Show InChI InChI=1S/C20H20N2O/c1-13-7-4-5-9-17(13)22-12-11-15-14(2)21-19-16(20(15)22)8-6-10-18(19)23-3/h4-10H,11-12H2,1-3H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Research Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7				J Med Chem 33: 527-33 (1990) BindingDB Entry DOI: 10.7270/Q2Z31XND
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM50286575 (2-(2-Propyl-5-o-tolyl-thiazol-4-yl)-pyridin-4-ylam...) Show SMILES CCCc1nc(c(s1)-c1ccccc1C)-c1cc(N)ccn1 Show InChI InChI=1S/C18H19N3S/c1-3-6-16-21-17(15-11-13(19)9-10-20-15)18(22-16)14-8-5-4-7-12(14)2/h4-5,7-11H,3,6H2,1-2H3,(H2,19,20)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	838	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit K+-stimulated ATPase activity				Bioorg Med Chem Lett 5: 543-546 (1995) Article DOI: 10.1016/0960-894X(95)00069-6 BindingDB Entry DOI: 10.7270/Q2R211CV
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394383 (N-methyl-1-[1-(phenylsulfonyl)-5-(3-thienyl)-1H-py...) Show SMILES CNCc1cc(-c2ccsc2)n(c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H16N2O2S2/c1-17-10-13-9-16(14-7-8-21-12-14)18(11-13)22(19,20)15-5-3-2-4-6-15/h2-9,11-12,17H,10H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394395 (1-[5-(2,4-Difluorophenyl)-1-(pyridin-3-ylsulfonyl)...) Show SMILES CNCc1cc(-c2ccc(F)cc2F)n(c1)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C17H15F2N3O2S/c1-20-9-12-7-17(15-5-4-13(18)8-16(15)19)22(11-12)25(23,24)14-3-2-6-21-10-14/h2-8,10-11,20H,9H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394391 (1-{5-(2-Fluorophenyl)-1-[(2-fluorophenyl)sulfonyl]...) Show SMILES CNCc1cc(-c2ccccc2F)n(c1)S(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H16F2N2O2S/c1-21-11-13-10-17(14-6-2-3-7-15(14)19)22(12-13)25(23,24)18-9-5-4-8-16(18)20/h2-10,12,21H,11H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394389 (Ethyl 1-(pyridazin-3-ylsulfonyl)-5-phenyl-1H-pyrro...) Show SMILES CCOC(=O)c1cc(-c2cccc(C)c2)n(c1)S(=O)(=O)c1cccnn1 Show InChI InChI=1S/C18H17N3O4S/c1-3-25-18(22)15-11-16(14-7-4-6-13(2)10-14)21(12-15)26(23,24)17-8-5-9-19-20-17/h4-12H,3H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032134 (2-(4-Fluoro-2-methyl-phenylamino)-4-(methyl-phenyl...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2ccc(O)cc12 Show InChI InChI=1S/C22H19FN4O/c1-14-12-15(23)8-10-19(14)24-22-25-20-11-9-17(28)13-18(20)21(26-22)27(2)16-6-4-3-5-7-16/h3-13,28H,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032135 (4-[Methyl-(2-o-tolylamino-quinazolin-4-yl)-amino]-...) Show SMILES CN(c1ccc(O)cc1)c1nc(Nc2ccccc2C)nc2ccccc12 Show InChI InChI=1S/C22H20N4O/c1-15-7-3-5-9-19(15)23-22-24-20-10-6-4-8-18(20)21(25-22)26(2)16-11-13-17(27)14-12-16/h3-14,27H,1-2H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032124 (CHEMBL315880 | N*4*-Methyl-N*4*-phenyl-N*2*-o-toly...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccccc2C)nc2ccsc12 Show InChI InChI=1S/C20H18N4S/c1-14-8-6-7-11-16(14)21-20-22-17-12-13-25-18(17)19(23-20)24(2)15-9-4-3-5-10-15/h3-13H,1-2H3,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032092 (CHEMBL330495 | N*2*-(4-Fluoro-2-methyl-phenyl)-N*4...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2ccccc12 Show InChI InChI=1S/C22H19FN4/c1-15-14-16(23)12-13-19(15)24-22-25-20-11-7-6-10-18(20)21(26-22)27(2)17-8-4-3-5-9-17/h3-14H,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032123 (8-(3-Dimethylamino-propoxy)-N*4*-methyl-N*4*-pheny...) Show SMILES CN(C)CCCOc1cccc2c(nc(Nc3ccccc3C)nc12)N(C)c1ccccc1 Show InChI InChI=1S/C27H31N5O/c1-20-12-8-9-16-23(20)28-27-29-25-22(15-10-17-24(25)33-19-11-18-31(2)3)26(30-27)32(4)21-13-6-5-7-14-21/h5-10,12-17H,11,18-19H2,1-4H3,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394392 (1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-...) Show SMILES CNCc1cc(-c2ccccc2F)n(c1)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C17H16FN3O2S/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14/h2-9,11-12,19H,10H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032137 (CHEMBL92757 | N*4*-Methyl-N*4*-phenyl-N*2*-o-tolyl...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccccc2C)nc2ccccc12 Show InChI InChI=1S/C22H20N4/c1-16-10-6-8-14-19(16)23-22-24-20-15-9-7-13-18(20)21(25-22)26(2)17-11-4-3-5-12-17/h3-15H,1-2H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032090 (4-(Methyl-phenyl-amino)-2-o-tolylamino-quinazolin-...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccccc2C)nc2ccc(O)cc12 Show InChI InChI=1S/C22H20N4O/c1-15-8-6-7-11-19(15)23-22-24-20-13-12-17(27)14-18(20)21(25-22)26(2)16-9-4-3-5-10-16/h3-14,27H,1-2H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032108 (4-[(4-Methoxy-phenyl)-methyl-amino]-1-methyl-2-o-t...) Show SMILES COc1ccc(cc1)[N+](\C)=c1\nc(Nc2ccccc2C)n(C)c2ccccc12 Show InChI InChI=1S/C24H24N4O/c1-17-9-5-7-11-21(17)25-24-26-23(20-10-6-8-12-22(20)28(24)3)27(2)18-13-15-19(29-4)16-14-18/h5-16H,1-4H3/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032116 (CHEMBL420621 | N*2*-(4-Fluoro-2-methyl-phenyl)-8-m...) Show SMILES COc1cccc2c(nc(Nc3ccc(F)cc3C)nc12)N(C)c1ccccc1 Show InChI InChI=1S/C23H21FN4O/c1-15-14-16(24)12-13-19(15)25-23-26-21-18(10-7-11-20(21)29-3)22(27-23)28(2)17-8-5-4-6-9-17/h4-14H,1-3H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394388 (1-[1-(1-Benzothien-2-ylsulfonyl)-5-phenyl-1H-pyrro...) Show SMILES CNc1cc(-c2ccccc2)n(c1)S(=O)(=O)c1cc2ccccc2s1 Show InChI InChI=1S/C19H16N2O2S2/c1-20-16-12-17(14-7-3-2-4-8-14)21(13-16)25(22,23)19-11-15-9-5-6-10-18(15)24-19/h2-13,20H,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032112 (CHEMBL421746 | N*2*-(4-Fluoro-2-methyl-phenyl)-N*4...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2ccsc12 Show InChI InChI=1S/C20H17FN4S/c1-13-12-14(21)8-9-16(13)22-20-23-17-10-11-26-18(17)19(24-20)25(2)15-6-4-3-5-7-15/h3-12H,1-2H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032119 (CHEMBL330283 | N*4*-(4-Methoxy-phenyl)-N*4*-methyl...) Show SMILES COc1ccc(cc1)N(C)c1nc(Nc2ccccc2C)nc2ccccc12 Show InChI InChI=1S/C23H22N4O/c1-16-8-4-6-10-20(16)24-23-25-21-11-7-5-9-19(21)22(26-23)27(2)17-12-14-18(28-3)15-13-17/h4-15H,1-3H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032131 (2-[4-(Methyl-phenyl-amino)-2-o-tolylamino-quinazol...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccccc2C)nc2c(OCCO)cccc12 Show InChI InChI=1S/C24H24N4O2/c1-17-9-6-7-13-20(17)25-24-26-22-19(12-8-14-21(22)30-16-15-29)23(27-24)28(2)18-10-4-3-5-11-18/h3-14,29H,15-16H2,1-2H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394394 (N-Methyl-1-[5-(2-methylphenyl)-1-(pyridin-3-ylsulf...) Show SMILES CNCc1cc(-c2ccccc2C)n(c1)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C18H19N3O2S/c1-14-6-3-4-8-17(14)18-10-15(11-19-2)13-21(18)24(22,23)16-7-5-9-20-12-16/h3-10,12-13,19H,11H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032152 (8-(3-Dimethylamino-propoxy)-N*2*-(4-fluoro-2-methy...) Show SMILES CN(C)CCCOc1cccc2c(nc(Nc3ccc(F)cc3C)nc12)N(C)c1ccccc1 Show InChI InChI=1S/C27H30FN5O/c1-19-18-20(28)14-15-23(19)29-27-30-25-22(12-8-13-24(25)34-17-9-16-32(2)3)26(31-27)33(4)21-10-6-5-7-11-21/h5-8,10-15,18H,9,16-17H2,1-4H3,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50031989 (1-[8-Hydroxymethyl-4-(4-hydroxy-2-methyl-phenylami...) Show SMILES CC(C)C(=O)c1cnc2c(CO)cccc2c1Nc1ccc(O)cc1C Show InChI InChI=1S/C21H22N2O3/c1-12(2)21(26)17-10-22-19-14(11-24)5-4-6-16(19)20(17)23-18-8-7-15(25)9-13(18)3/h4-10,12,24-25H,11H2,1-3H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	7.0	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of K+ -stimulated gastric ATPase activity was measured using lyophilized gastric vesicles at pH 7				J Med Chem 38: 2748-62 (1995) BindingDB Entry DOI: 10.7270/Q2ZK5FPD
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032125 (CHEMBL327983 | N*2*-(4-Chloro-2-methyl-phenyl)-N*4...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(Cl)cc2C)nc2ccccc12 Show InChI InChI=1S/C22H19ClN4/c1-15-14-16(23)12-13-19(15)24-22-25-20-11-7-6-10-18(20)21(26-22)27(2)17-8-4-3-5-9-17/h3-14H,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032096 (8-Methoxy-N*4*-methyl-N*4*-phenyl-N*2*-o-tolyl-qui...) Show SMILES COc1cccc2c(nc(Nc3ccccc3C)nc12)N(C)c1ccccc1 Show InChI InChI=1S/C23H22N4O/c1-16-10-7-8-14-19(16)24-23-25-21-18(13-9-15-20(21)28-3)22(26-23)27(2)17-11-5-4-6-12-17/h4-15H,1-3H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032148 (CHEMBL329852 | N*4*-Methyl-N*2*,N*4*-di-o-tolyl-qu...) Show SMILES CN(c1ccccc1C)c1nc(Nc2ccccc2C)nc2ccccc12 Show InChI InChI=1S/C23H22N4/c1-16-10-4-7-13-19(16)24-23-25-20-14-8-6-12-18(20)22(26-23)27(3)21-15-9-5-11-17(21)2/h4-15H,1-3H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032145 (CHEMBL91804 | N*2*-(4-Fluoro-2-methyl-phenyl)-N*4*...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2c(OCCCN3CCOCC3)cccc12 Show InChI InChI=1S/C29H32FN5O2/c1-21-20-22(30)12-13-25(21)31-29-32-27-24(28(33-29)34(2)23-8-4-3-5-9-23)10-6-11-26(27)37-17-7-14-35-15-18-36-19-16-35/h3-6,8-13,20H,7,14-19H2,1-2H3,(H,31,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394386 (N-Methyl-1-[5-phenyl-1-(3-thienylsulfonyl)-1H-pyrr...) Show SMILES CNCc1cc(-c2ccccc2)n(c1)S(=O)(=O)c1ccsc1 Show InChI InChI=1S/C16H16N2O2S2/c1-17-10-13-9-16(14-5-3-2-4-6-14)18(11-13)22(19,20)15-7-8-21-12-15/h2-9,11-12,17H,10H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394378 (Ethyl 1-[(4-methoxyphenyl)sulfonyl]-5-phenyl-1H-py...) Show SMILES CCOC(=O)c1cc(-c2ccccc2)n(c1)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C20H19NO5S/c1-3-26-20(22)16-13-19(15-7-5-4-6-8-15)21(14-16)27(23,24)18-11-9-17(25-2)10-12-18/h4-14H,3H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032014 (1-[8-(1-Hydroxy-ethyl)-4-(4-hydroxy-2-methyl-pheny...) Show SMILES CCCC(=O)c1cnc2c(cccc2c1Nc1ccc(O)cc1C)C(C)O Show InChI InChI=1S/C22H24N2O3/c1-4-6-20(27)18-12-23-21-16(14(3)25)7-5-8-17(21)22(18)24-19-10-9-15(26)11-13(19)2/h5,7-12,14,25-26H,4,6H2,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	7.0	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of K+ -stimulated gastric ATPase activity was measured using lyophilized gastric vesicles at pH 7				J Med Chem 38: 2748-62 (1995) BindingDB Entry DOI: 10.7270/Q2ZK5FPD
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394390 (1-[5-(2-Fluorophenyl)-1-{[3-(methylsulfonyl)phenyl...) Show SMILES CNCc1cc(-c2ccccc2F)n(c1)S(=O)(=O)c1cccc(c1)S(C)(=O)=O Show InChI InChI=1S/C19H19FN2O4S2/c1-21-12-14-10-19(17-8-3-4-9-18(17)20)22(13-14)28(25,26)16-7-5-6-15(11-16)27(2,23)24/h3-11,13,21H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032149 (CHEMBL330222 | N*4*-Methyl-N*2*,N*4*-diphenyl-quin...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccccc2)nc2ccccc12 Show InChI InChI=1S/C21H18N4/c1-25(17-12-6-3-7-13-17)20-18-14-8-9-15-19(18)23-21(24-20)22-16-10-4-2-5-11-16/h2-15H,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032094 (CHEMBL92968 | N*2*,N*4*-Dimethyl-N*2*,N*4*-dipheny...) Show SMILES CN(c1ccccc1)c1nc(N(C)c2ccccc2)c2ccccc2n1 Show InChI InChI=1S/C22H20N4/c1-25(17-11-5-3-6-12-17)21-19-15-9-10-16-20(19)23-22(24-21)26(2)18-13-7-4-8-14-18/h3-16H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032000 (1-[6-Hydroxy-4-(4-hydroxy-2-methyl-phenylamino)-qu...) Show SMILES CCCC(=O)c1cnc2ccc(O)cc2c1Nc1ccc(O)cc1C Show InChI InChI=1S/C20H20N2O3/c1-3-4-19(25)16-11-21-18-8-6-14(24)10-15(18)20(16)22-17-7-5-13(23)9-12(17)2/h5-11,23-24H,3-4H2,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	7.0	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of K+ -stimulated gastric ATPase activity was measured using lyophilized gastric vesicles at pH 7				J Med Chem 38: 2748-62 (1995) BindingDB Entry DOI: 10.7270/Q2ZK5FPD
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032129 (8-Methoxy-N*2*,N*4*-dimethyl-N*2*,N*4*-diphenyl-qu...) Show SMILES COc1cccc2c(nc(nc12)N(C)c1ccccc1)N(C)c1ccccc1 Show InChI InChI=1S/C23H22N4O/c1-26(17-11-6-4-7-12-17)22-19-15-10-16-20(28-3)21(19)24-23(25-22)27(2)18-13-8-5-9-14-18/h4-16H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394387 (US10308605, Example 140) Show SMILES COC(=O)c1cn(c(Br)c1C)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C13H12BrNO4S/c1-9-11(13(16)19-2)8-15(12(9)14)20(17,18)10-6-4-3-5-7-10/h3-8H,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032138 (8-Methoxy-N*4*-o-tolyl-quinazoline-2,4-diamine | C...) Show SMILES COc1cccc2c(Nc3ccccc3C)nc(N)nc12 Show InChI InChI=1S/C16H16N4O/c1-10-6-3-4-8-12(10)18-15-11-7-5-9-13(21-2)14(11)19-16(17)20-15/h3-9H,1-2H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394393 (N-Methyl-3-({4-[(methylamino)methyl]-2-phenyl-1H-p...) Show SMILES CNCc1cc(-c2ccccc2)n(c1)S(=O)(=O)c1cccc(c1)C(=O)NC Show InChI InChI=1S/C20H21N3O3S/c1-21-13-15-11-19(16-7-4-3-5-8-16)23(14-15)27(25,26)18-10-6-9-17(12-18)20(24)22-2/h3-12,14,21H,13H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM394377 (N-Methyl-1-{5-(3-methylphenyl)-1-[(4-methylphenyl)...) Show SMILES CNCc1cc(-c2cccc(C)c2)n(c1)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C20H22N2O2S/c1-15-7-9-19(10-8-15)25(23,24)22-14-17(13-21-3)12-20(22)18-6-4-5-16(2)11-18/h4-12,14,21H,13H2,1-3H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Washington University					Assay Description According to the method [Biochem. Biophys. Acta., 728, 31 (1983)] of Wallmark et al., a gastric mucous membrane microsomal fraction was prepared from...				J Med Chem 52: 2188-91 (2009) BindingDB Entry DOI: 10.7270/Q2FF3VPK
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032118 (CHEMBL93369 | N*2*-(4-Fluoro-2-methyl-phenyl)-8-me...) Show SMILES COc1cccc2c(nc(Nc3ccc(F)cc3C)nc12)N(C)c1ccccc1C Show InChI InChI=1S/C24H23FN4O/c1-15-8-5-6-10-20(15)29(3)23-18-9-7-11-21(30-4)22(18)27-24(28-23)26-19-13-12-17(25)14-16(19)2/h5-14H,1-4H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50001224 ((8-Methoxy-quinolin-4-yl)-o-tolyl-amine | CHEMBL11...) Show SMILES COc1cccc2c(Nc3ccccc3C)ccnc12 Show InChI InChI=1S/C17H16N2O/c1-12-6-3-4-8-14(12)19-15-10-11-18-17-13(15)7-5-9-16(17)20-2/h3-11H,1-2H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase				J Med Chem 35: 3413-22 (1992) BindingDB Entry DOI: 10.7270/Q2CN74J2
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032113 (2-[2-(4-Fluoro-2-methyl-phenylamino)-4-(methyl-phe...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2c(OCCO)cccc12 Show InChI InChI=1S/C24H23FN4O2/c1-16-15-17(25)11-12-20(16)26-24-27-22-19(9-6-10-21(22)31-14-13-30)23(28-24)29(2)18-7-4-3-5-8-18/h3-12,15,30H,13-14H2,1-2H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032120 (8-Methoxy-N*4*-methyl-N*2*,N*4*-di-o-tolyl-quinazo...) Show SMILES COc1cccc2c(nc(Nc3ccccc3C)nc12)N(C)c1ccccc1C Show InChI InChI=1S/C24H24N4O/c1-16-10-5-7-13-19(16)25-24-26-22-18(12-9-15-21(22)29-4)23(27-24)28(3)20-14-8-6-11-17(20)2/h5-15H,1-4H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1 (Sus scrofa (Pig))	BDBM50008977 ((8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-...) Show SMILES Cc1nc2c(OCc3ccccc3)cccn2c1CC#N Show InChI InChI=1S/C17H15N3O/c1-13-15(9-10-18)20-11-5-8-16(17(20)19-13)21-12-14-6-3-2-4-7-14/h2-8,11H,9,12H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Research Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7				J Med Chem 33: 527-33 (1990) BindingDB Entry DOI: 10.7270/Q2Z31XND
					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032139 (CHEMBL95046 | N*4*-(4-Fluoro-phenyl)-N*4*-methyl-N...) Show SMILES CN(c1ccc(F)cc1)c1nc(Nc2ccccc2C)nc2ccccc12 Show InChI InChI=1S/C22H19FN4/c1-15-7-3-5-9-19(15)24-22-25-20-10-6-4-8-18(20)21(26-22)27(2)17-13-11-16(23)12-14-17/h3-14H,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032122 ((4-Fluoro-2-methyl-phenyl)-(6-methyl-1-o-tolyl-2,3...) Show SMILES Cc1ccccc1N1CCc2c1c1cccc(C)c1nc2Nc1ccc(F)cc1C Show InChI InChI=1S/C26H24FN3/c1-16-7-4-5-10-23(16)30-14-13-21-25(30)20-9-6-8-17(2)24(20)29-26(21)28-22-12-11-19(27)15-18(22)3/h4-12,15H,13-14H2,1-3H3,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032141 (CHEMBL92888 | [2-(4-Fluoro-2-methyl-phenylamino)-4...) Show SMILES CCOC(=O)COc1cccc2c(nc(Nc3ccc(F)cc3C)nc12)N(C)c1ccccc1 Show InChI InChI=1S/C26H25FN4O3/c1-4-33-23(32)16-34-22-12-8-11-20-24(22)29-26(28-21-14-13-18(27)15-17(21)2)30-25(20)31(3)19-9-6-5-7-10-19/h5-15H,4,16H2,1-3H3,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032093 (CHEMBL96456 | N*2*-(4-Fluoro-2-methyl-phenyl)-N*4*...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2sccc12 Show InChI InChI=1S/C20H17FN4S/c1-13-12-14(21)8-9-17(13)22-20-23-18(16-10-11-26-19(16)24-20)25(2)15-6-4-3-5-7-15/h3-12H,1-2H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Sus scrofa (Pig))	BDBM50032107 (8-Fluoro-N*2*-(4-fluoro-2-methyl-phenyl)-N*4*-meth...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2c(F)cccc12 Show InChI InChI=1S/C22H18F2N4/c1-14-13-15(23)11-12-19(14)25-22-26-20-17(9-6-10-18(20)24)21(27-22)28(2)16-7-4-3-5-8-16/h3-13H,1-2H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair

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