Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Activin receptor type-1 (Homo sapiens (Human)) | BDBM621073 (Synthesis of 5-(3-(4-fluorobenzylamino)-1-(6-methy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM518186 (US11111247, Example 17) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.850 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM518192 (US11111247, Example 22) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575192 (US11459329, Example 66) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575148 (US11459329, Example 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575137 (US11459329, Example 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575135 (US11459329, Example 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575133 (US11459329, Example 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM603776 (US11654147, Compound 213) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q27085CT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575153 (US11459329, Example 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575155 (US11459329, Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575162 (US11459329, Example 36) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575163 (US11459329, Example 37) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575164 (US11459329, Example 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575166 (US11459329, Example 40) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575174 (US11459329, Example 48) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575175 (US11459329, Example 49) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575176 (US11459329, Example 50) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575178 (US11459329, Example 52) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575180 (US11459329, Example 54) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575184 (US11459329, Example 58) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575188 (US11459329, Example 62) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575193 (US11459329, Example 67) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575194 (US11459329, Example 68) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575198 (1-(4-(3-(7-(1-Ethyl-1H-imidazol-4-yl)-1,8-naphthyr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM640389 (US11840546, Example 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM640390 (US11840546, Example 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM640391 (US11840546, Example 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM640392 (US11840546, Example 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50560457 (CHEMBL4790396) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assay | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127418 BindingDB Entry DOI: 10.7270/Q2WW7NDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575127 (US11459329, Example 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575128 (US11459329, Example 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [147-509] (Homo sapiens (Human)) | BDBM575132 (US11459329, Example 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description ALK2 (aa 147-end) was obtained from BPS biosciences. The enzymatic assays were conducted in white 384-well polystyrene plates in a final volume of 8 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM102619 (K02288a | US10688093, Compound 382_0087_0284 | US1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM518173 (US11111247, Example 9) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [R206H] (Homo sapiens (Human)) | BDBM488058 (N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4...) | PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN; THE UNIVERSITY OF TOKYO US Patent | Assay Description R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe... | US Patent US10954216 (2021) BindingDB Entry DOI: 10.7270/Q2P84G0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM518193 (US11111247, Example 23) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM518194 (US11111247, Example 24) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM603863 (US11654147, Compound 313 | US11654147, Compound 33...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q27085CT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528203 (CHEMBL4434694) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of ALK2 G328V mutant (unknown origin) | J Med Chem 63: 4978-4996 (2020) Article DOI: 10.1021/acs.jmedchem.0c00395 BindingDB Entry DOI: 10.7270/Q2MK6HB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528195 (CHEMBL4435320) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of ALK2 R258G mutant (unknown origin) | J Med Chem 63: 4978-4996 (2020) Article DOI: 10.1021/acs.jmedchem.0c00395 BindingDB Entry DOI: 10.7270/Q2MK6HB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528195 (CHEMBL4435320) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of ALK2 G328V mutant (unknown origin) | J Med Chem 63: 4978-4996 (2020) Article DOI: 10.1021/acs.jmedchem.0c00395 BindingDB Entry DOI: 10.7270/Q2MK6HB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM621068 (US20230303562, Example 6) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.36 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM518135 (US11111247, Example 1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [R206H] (Homo sapiens (Human)) | BDBM488080 (N-(4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)...) | PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN; THE UNIVERSITY OF TOKYO US Patent | Assay Description R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe... | US Patent US10954216 (2021) BindingDB Entry DOI: 10.7270/Q2P84G0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50596223 (CHEMBL5200241) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM603850 (US11654147, Compound 298) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q27085CT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM603862 (US11654147, Compound 312 | US11654147, Compound 33...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q27085CT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528196 (CHEMBL4575655) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay | J Med Chem 63: 4978-4996 (2020) Article DOI: 10.1021/acs.jmedchem.0c00395 BindingDB Entry DOI: 10.7270/Q2MK6HB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50528195 (CHEMBL4435320) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay | J Med Chem 63: 4978-4996 (2020) Article DOI: 10.1021/acs.jmedchem.0c00395 BindingDB Entry DOI: 10.7270/Q2MK6HB1 | |||||||||||
More data for this Ligand-Target Pair |
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