Compound Name (alphabetical) | Enz. Inhib. Data | ITC Data | Binding Targets | Alternate Compound Names |
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Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
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BDBM10870
| 110 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - β-Carbonic anhydrase 2 (CA 2)
- Alpha carbonic anhydrase
- Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonate dehydratase
- Carbonic Anhydrase (hpCA)
- Carbonic Anhydrase (mtCA 1)
- Carbonic Anhydrase (mtCA 3)
- Carbonic Anhydrase 2 (Can2)
- Carbonic Anhydrase III
- Carbonic Anhydrase IV
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 2
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 9
- Carbonic anhydrase, alpha family
- Carbonic anhydrases; II & IX
- Delta carbonic anhydrase
- beta-Carbonic Anhydrase
| - 2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfonamide
- Aminobenzolamide 12
- CHEMBL268439
- aminobenzolamide 17a
- aminobenzolamide deriv. 43
- aromatic/heteroaromatic sulfonamide 15
|
BDBM23971
| 16 | 91 | 3 | 0 | 0 | 0 | 0 | 0 | - Aminopeptidase
- Aminopeptidase B
- Aminopeptidase N
- Bacterial leucyl aminopeptidase
- Collagenase
- Cystinyl aminopeptidase
- Cytosol aminopeptidase
- Dipeptidyl peptidase 4
- Gelatinase 2 (MMP-2)
- HDACs
- Leucine aminopeptidase
- Leucyl-cystinyl aminopeptidase
- Leukotriene A4 hydrolase
- Oligopeptide transporter small intestine isoform
- Phospholipase A2, membrane associated
- Zinc aminopeptidase
| - (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
- Bestatin
- CHEMBL29292
- Ubenimex
|
BDBM50020712
| 78 | 26 | 5 | 1 | 0 | 0 | 0 | 0 | - 5-Hydroxytryptamine receptor 6 (5-HT6)
- 5-hydroxytryptamine receptor 1A (5-HT1A)
- 5-hydroxytryptamine receptor 2C
- ADRB2
- Adrenergic Alpha
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Bile salt export pump
- CHRM5
- Calcium channel
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- DOPAMINE
- Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
- Dopamine D5 receptor
- Dopamine Transporter (DAT)
- HTR6
- High affinity nerve growth factor receptor
- Histamine H1 receptor
- Histamine H2 receptor
- Histamine H4 receptor
- Histamine receptor (H3)
- Monoamine transporters; serotonin & dopamine
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Norepinephrine Monoamine transporters
- Norepinephrine transporter
- Potassium voltage-gated channel subfamily H member 2
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Serum albumin
- Sigma non-opioid intracellular receptor 1
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 7 subunit alpha
- Sodium channel protein type 9 subunit alpha
- Sodium channel protein type I I alpha subunit
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
- Voltage-gated L-type calcium channel
- Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2)
- adrenergic Alpha2
| - 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
- 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine
- 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
- 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine
- 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine
- 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene
- 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
- 5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene
- AMITRIPTYLINE
- Amitriptylin
- CHEMBL629
|
BDBM50224883
| 109 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | - 5'-AMP-activated protein kinase subunit beta-1
- BDNF/NT-3 growth factors receptor
- CDK7/Cyclin H/MNAT1
- CaM kinase I alpha
- CaM kinase IV
- Casein kinase I
- Casein kinase I isoform alpha
- Casein kinase I isoform delta
- Casein kinase II alpha
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-dependent kinase 1
- Cyclin-dependent kinase 2
- Cyclin-dependent kinase 6
- Cyclin-dependent kinase 9
- Death-associated protein kinase 3
- Dual specificity protein kinase CLK2
- Dual specificity protein kinase CLK4
- Dual-specificity tyrosine-phosphorylation regulated kinase 1A
- Dual-specificity tyrosine-phosphorylation regulated kinase 3
- Ephrin receptor
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 3
- Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
- Glycogen synthase kinase-3
- Glycogen synthase kinase-3 beta
- High affinity nerve growth factor receptor
- Homeodomain-interacting protein kinase 2 (HIPK2)
- Inhibitor of NF-kappa-B kinase (IKK)
- Insulin receptor
- Insulin-like growth factor I receptor
- Interleukin-1 receptor-associated kinase 1
- Interleukin-1 receptor-associated kinase 4
- LIM domain kinase 1
- MAP kinase-activated protein kinase 2
- MAP kinase-activated protein kinase 3
- MAP kinase-activated protein kinase 5
- MAP kinase-interacting serine/threonine-protein kinase 2
- MAP/microtubule affinity-regulating kinase 2
- Mast/stem cell growth factor receptor Kit
- Misshapen-like kinase 1
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 13 (MAPK13)
- Mitogen-activated protein kinase 2
- Mitogen-activated protein kinase kinase kinase 9 (MLK1)
- Mixed lineage kinase 7
- Muscle, skeletal receptor tyrosine protein kinase
- NUAK family SNF1-like kinase 1
- Non-receptor tyrosine-protein kinase TYK2
- PAK1
- PDZ-binding kinase
- Protein kinase C (PKC)
- Protein kinase C delta type
- Protein kinase C, gamma
- Protein kinase N2
- Proto-oncogene tyrosine-protein kinase Src
- Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1)
- RAC-alpha serine/threonine-protein kinase AKT1
- Receptor tyrosine-protein kinase erbB-2
- Receptor tyrosine-protein kinase erbB-4
- Rho-associated protein kinase 1
- Rho-associated protein kinase 2
- Ribosomal protein S6 kinase (P70S6K)
- Ribosomal protein S6 kinase alpha 4
- Ribosomal protein S6 kinase alpha 5
- Ribosomal protein S6 kinase alpha-3
- SRC
- Serine/threonine protein kinase NLK
- Serine/threonine-protein kinase 31
- Serine/threonine-protein kinase 33
- Serine/threonine-protein kinase AKT
- Serine/threonine-protein kinase AKT2
- Serine/threonine-protein kinase CHK2
- Serine/threonine-protein kinase Chk1
- Serine/threonine-protein kinase D2
- Serine/threonine-protein kinase D3
- Serine/threonine-protein kinase DCLK2
- Serine/threonine-protein kinase MRCK alpha
- Serine/threonine-protein kinase Nek11
- Serine/threonine-protein kinase Nek2
- Serine/threonine-protein kinase Nek3
- Serine/threonine-protein kinase Nek4
- Serine/threonine-protein kinase PAK 4
- Serine/threonine-protein kinase PIM
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase PLK3
- Serine/threonine-protein kinase PRKX
- Serine/threonine-protein kinase SRPK1
- Serine/threonine-protein kinase SRPK3
- Serine/threonine-protein kinase Sgk1
- Serine/threonine-protein kinase TAO1
- Serine/threonine-protein kinase TBK1
- Serine/threonine-protein kinase WNK2
- Serine/threonine-protein kinase c-TAK1
- Serine/threonine-protein kinase pim-2
- Testis-specific serine/threonine-protein kinase 1
- Testis-specific serine/threonine-protein kinase 2
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase Blk
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
- p38 delta/gamma
| - 7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,16-dioxa-2,4,19,21-tetraaza-tricyclo[15.3.1.0*5,10*]henicosa-1(21),5,7,9,17,19-hexaene-18-crbonitrile
- CHEMBL248757
|