Compound Name (alphabetical) | Enz. Inhib. Data | ITC Data | Binding Targets | Alternate Compound Names |
---|
Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
---|
BDBM10018
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Aromatase (CYP19)
- Steryl-sulfatase
| - (4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}-2-fluorophenyl) sulfamate
- JMC503540 Compound 3
- YM511-based dual aromatase-sulfatase inhibitor (DASI) 5
- dual aromatase-sulfatase inhibitor 5
|
BDBM10019
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Aromatase (CYP19)
- Steryl-sulfatase
| - (2-chloro-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate
- JMC503540 Compound 4
- YM511-based dual aromatase-sulfatase inhibitor (DASI) 6
- dual aromatase-sulfatase inhibitor 6
|
BDBM10021
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Aromatase (CYP19)
- Steryl-sulfatase
| - (3-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate
- JMC503540 Compound 6
- YM511-based dual aromatase-sulfatase inhibitor (DASI) 8
- dual aromatase-sulfatase inhibitor 8
|
BDBM10025
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Aromatase (CYP19)
- Thromboxane A2 Synthase (P450 TxA2)
| - 5-(1H-imidazol-1-ylmethyl)-7,8-dihydroquinoline
- 5-[(Imidazol-1-yl)methyl]-7,8-dihydroquinoline
- CHEMBL53068
- dihydroquinoline 44
|
BDBM100259
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - ADAM17
- Alpha trans-inducing protein (VP16)
- COUP transcription factor 2 isoform a
- Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
| - 2-hydroxy-3-[(E)-3-(4-nitrophenyl)-1-oxoprop-2-enyl]-1-cyclohepta-2,4,6-trienone
- 2-hydroxy-3-[(E)-3-(4-nitrophenyl)acryloyl]cyclohepta-2,4,6-trien-1-one
- 2-hydroxy-3-[(E)-3-(4-nitrophenyl)prop-2-enoyl]cyclohepta-2,4,6-trien-1-one
- 3-[(E)-3-(4-nitrophenyl)prop-2-enoyl]-2-oxidanyl-cyclohepta-2,4,6-trien-1-one
- MLS002701851
- SMR001565443
- cid_6302331
|
BDBM10027
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Aromatase (CYP19)
- Thromboxane A2 Synthase (P450 TxA2)
| - 5-[2-(1H-imidazol-1-yl)ethyl]-7,8-dihydroquinoline
- 5-[2-(Imidazol-1-yl)ethyl]-7,8-dihydroquinoline
- CHEMBL293122
- dihydroquinoline 31
|
BDBM100349
| 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | - Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase JAK3
| |
BDBM10041
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Aromatase (CYP19)
- Thromboxane A2 Synthase (P450 TxA2)
| - 7-(1H-imidazol-1-ylmethyl)isoquinoline
- 7-[(Imidazol-1-yl)methyl]isoquinoline
- CHEMBL298720
- isoquinoline 56
|
BDBM100740
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Cathepsin G
- Chymase
- Leukocyte elastase
| - CHEMBL391608
- US8507714, 29
|
BDBM100750
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Cathepsin G
- Chymase
- Leukocyte elastase
| - CHEMBL2397003
- US8507714, 239
|
BDBM101302
| 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - Amine oxidase [flavin-containing] A
- Amine oxidase [flavin-containing] B
- Lysine-specific histone demethylase 1A
| - CHEMBL3108900
- US8524717, 57
|
BDBM101309
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| |
BDBM101356
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| - US9695151, 22
- US9695151, 23
|
BDBM101358
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| - US9695151, 24
- US9695151, 25
|
BDBM101360
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| - US9695151, 26
- US9695151, 27
|
BDBM101383
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| |
BDBM101386
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| |
BDBM101404
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| - US9695152, 25
- US9695152, 26
|
BDBM101408
| 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | - Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
| - US9695152, 29
- US9695152, 30
|
BDBM10145
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Beta-secretase 1
- Beta-secretase 2
- Cathepsin D
- HIV-1 Protease
| - lysine sulfonamide analogue 9
- methyl N-[(1S)-1-{[(5R)-5-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-6-hydroxyhexyl]carbamoyl}-2-phenylethyl]-N-methylcarbamate
- sulfonamide tricyclic analogue, 9
|
BDBM101504
| 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | - Serine/threonine-protein kinase PAK 4
| - US8524699, 91
- US8524710, 82
- US8530652, 31
|
BDBM101515
| 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | - Serine/threonine-protein kinase PAK 4
| - US8524699, 26
- US8530652, 42
- US8530670, 31
|
BDBM101763
| 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | - Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
| - CHEMBL2057909
- US8530490, 23
|
BDBM101847
| 0 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | - Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
| - CHEMBL2147985
- US8530490, 110
|
BDBM101888
| 0 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | - Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
| - CHEMBL1234485
- US8530490, 158
|
BDBM102132
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102134
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102135
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102138
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102139
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102141
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102143
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102144
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102145
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102151
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102152
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102153
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102157
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102164
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102174
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102176
| 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | - Orexin receptor type 1
- Orexin receptor type 2
| |
BDBM102177
| 2 | 0 | 2 | 0 | 0 | 0 |