Compound Name (alphabetical) | Enz. Inhib. Data | ITC Data | Binding Targets | Alternate Compound Names |
---|
Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
---|
BDBM214798
| 26 | 0 | 0 | 25 | 0 | 0 | 0 | 0 | - κ opioid receptor (KOR D138A)
- κ opioid receptor (KOR D138N)
- κ opioid receptor (KOR E297A)
- κ opioid receptor (KOR H291A)
- κ opioid receptor (KOR H291F)
- κ opioid receptor (KOR I135A)
- κ opioid receptor (KOR I294A)
- κ opioid receptor (KOR I316A)
- κ opioid receptor (KOR K200A)
- κ opioid receptor (KOR K227A)
- κ opioid receptor (KOR L212A)
- κ opioid receptor (KOR M142A)
- κ opioid receptor (KOR M226A)
- κ opioid receptor (KOR Q115A)
- κ opioid receptor (KOR Y119A)
- κ opioid receptor (KOR Y119F)
- κ opioid receptor (KOR Y139A)
- κ opioid receptor (KOR Y139F)
- κ opioid receptor (KOR Y312A)
- κ opioid receptor (KOR Y312F)
- κ opioid receptor (KOR Y313A)
- κ opioid receptor (KOR Y313F)
- κ opioid receptor (KOR Y320A)
- κ opioid receptor (KOR Y320F)
- κ opioid receptor (KOR Y66A)
- Kappa-type opioid receptor
| - Dynorphin A (1-17)
- YGGFLRRIRPKLK
|
BDBM214799
| 26 | 0 | 0 | 25 | 0 | 0 | 0 | 0 | - κ opioid receptor (KOR D138A)
- κ opioid receptor (KOR D138N)
- κ opioid receptor (KOR E297A)
- κ opioid receptor (KOR H291A)
- κ opioid receptor (KOR H291F)
- κ opioid receptor (KOR I135A)
- κ opioid receptor (KOR I294A)
- κ opioid receptor (KOR I316A)
- κ opioid receptor (KOR K200A)
- κ opioid receptor (KOR K227A)
- κ opioid receptor (KOR L212A)
- κ opioid receptor (KOR M142A)
- κ opioid receptor (KOR M226A)
- κ opioid receptor (KOR Q115A)
- κ opioid receptor (KOR Y119A)
- κ opioid receptor (KOR Y119F)
- κ opioid receptor (KOR Y139A)
- κ opioid receptor (KOR Y139F)
- κ opioid receptor (KOR Y312A)
- κ opioid receptor (KOR Y312F)
- κ opioid receptor (KOR Y313A)
- κ opioid receptor (KOR Y313F)
- κ opioid receptor (KOR Y320A)
- κ opioid receptor (KOR Y320F)
- κ opioid receptor (KOR Y66A)
- Kappa-type opioid receptor
| |
BDBM50329427
| 0 | 51 | 0 | 0 | 0 | 0 | 0 | 0 | - ALK tyrosine kinase receptor
- Aurora kinase A
- Aurora kinase B
- CDK2/Cyclin A/Cyclin A1
- CDK2/Cyclin E/G1/S-specific cyclin E2
- Cdc7 Kinase
- Cell division cycle 7-related protein kinase
- Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
- Cyclin-Dependent Kinase 4 (CDK4)
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-Dependent Kinase 9 (CDK9)
- Dual specificity protein kinase TTK
- Eukaryotic elongation factor 2 kinase
- Fibroblast growth factor receptor 1
- Focal adhesion kinase 1
- Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
- Glycogen synthase kinase-3 beta
- Hepatocyte growth factor receptor
- High affinity nerve growth factor receptor
- Inhibitor of NF-kappa-B kinase (IKK)
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon
- Insulin receptor
- Insulin-like growth factor I receptor
- MAP kinase p38 beta
- MAP kinase-activated protein kinase 2
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 14
- PKC alpha and beta-2
- Pancreatic endoplasmic reticulum kinase (PERK)
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1)
- RAC-alpha serine/threonine-protein kinase AKT1
- Serine/threonine-protein kinase Chk1
- Serine/threonine-protein kinase MST4
- Serine/threonine-protein kinase NEK6
- Serine/threonine-protein kinase NIM1
- Serine/threonine-protein kinase PAK 4
- Serine/threonine-protein kinase PIM
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase TAO1
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase BRK
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase ZAP-70
- Tyrosine-protein kinase receptor FLT3
- cAMP-dependent protein kinase (PKA)
| - 5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide
- CHEMBL1270230
- US9670191, U1
|
BDBM50380728
| 8 | 32 | 0 | 11 | 0 | 0 | 0 | 0 | | |
BDBM577
| 28 | 10 | 1 | 6 | 0 | 0 | 0 | 0 | - Cathepsin D
- Cytochrome P450 3A
- Cytochrome P450 3A5 (CYP3A5)
- Gag polyprotein
- HIV WT-A pol protein (wild-type clade A)
- HIV WT-B pol protein (wild-type clade B)
- HIV WT-C pol protein (wild-type clade C)
- HIV-1 Protease
- HIV-1 Protease AE
- HIV-1 Protease AE Mutant (V82F)
- HIV-1 Protease AE-P
- HIV-1 Protease AE-P Mutant (F82V)
- HIV-1 Protease B Subtype
- HIV-1 Protease B Subtype Mutant (V82F)
- HIV-1 Protease Mutant (I50V)
- HIV-1 Protease Mutant (L10I,L19Q,K20R,E35D,M36I, ..)
- HIV-1 Protease Mutant (L10I/L90M)
- HIV-1 Protease Mutant (M46I,L63P,A71V,V82F,I84V)
- HIV-1 Protease Mutant (M46I/I54V)
- HIV-1 Protease Mutant (V82A/I84V)
- HIV-1 Protease Mutant M1 (L10I, G48V, I54V, L63P, V82A)
- HIV-1 Protease Mutant M2 (D30N, L63P, N88D)
- HIV-1 Protease Mutant M3 (L10I, L63P, A71V, G73S, I84V, L90M)
- HIV-1 Protease Mutant, MDR-HM
- HIV-1 Protease Mutant, MDR-QM
- HIV-1 isolate WT-control pol protein (CNDO control strain)
- HIV-1 protease
- Human immunodeficiency virus type 1 protease
- MDR1
- MDRC4
- P-glycoprotein 1
| - (3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate
- 141W94
- APV
- Agenerase
- Amprenavir
- CHEMBL116
- VX-478
|
BDBM8610
| 8 | 38 | 5 | 0 | 0 | 0 | 0 | 0 | - Aromatase (CYP19)
- Bile salt export pump
- Bile salt export pump (BSEP)
- Cytochrome P450 11B1, mitochondrial
- Cytochrome P450 11B2 (CYP11B2)
- Cytochrome P450 125 (CYP125)
- Cytochrome P450 142 (CYP142)
- Cytochrome P450 144 (CYP144)
- Cytochrome P450 17A1
- Cytochrome P450 1A
- Cytochrome P450 24A1
- Cytochrome P450 27B1
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- P-glycoprotein 1
- Phylloquinone omega-hydroxylase CYP4F2
- Sterol 14-alpha demethylase (CYP51)
- Uridine-5'-diphosphoglucuronosyltransferase 1A1
| - 1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
- 24F2-1,25(OH)D3
- CHEMBL75
- KTZ
- Ketoconazole
- Ketoconazole (k)
- US9138393, Ketoconozole
- US9144538, Ketoconozole
|
BDBM86202
| 51 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - 5-Hydroxytryptamine receptor 6 (5-HT6)
- 5-Hydroxytryptamine receptor 7 (5-HT7)
- 5-hydroxytryptamine receptor 1A (5-HT1A)
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 3A
- ADRB2
- Adrenergic alpha1B
- Adrenergic receptor beta
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- CHRM5
- Calcium channel
- Cannabinoid receptor 1
- Cholinergic, Nicotinic Alpha3Beta2
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Dopamine D5 receptor
- Dopamine receptor
- Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)
- Histamine H1 receptor
- Histamine H2 Receptor
- Histamine H4 receptor
- Ionotropic glutamate receptor NMDA 1/2D
- Kappa-type opioid receptor
- Monoamine transporters; serotonin & dopamine
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Neuronal acetylcholine receptor
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor; alpha2/beta2
- Oxytocin receptor
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
- Vasopressin V1b receptor
- Vasopressin V2 receptor (V2)
| - CAS_778
- DL-homocysteine
- NSC_778
|