Compound Name (alphabetical) | Enz. Inhib. Data | ITC Data | Binding Targets | Alternate Compound Names |
---|
Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
---|
BDBM14027
| 8 | 48 | 1 | 1 | 0 | 0 | 0 | 0 | - C-C chemokine receptor type 2
- C-C motif chemokine 2
- Cell division control protein 42 homolog
- Myosin light chain kinase, smooth muscle
- Myotonin-protein kinase
- PKA
- Potassium voltage-gated channel subfamily H member 2
- Protein kinase C, epsilon
- Protein kinase N1
- Protein kinase N2
- Protein kinase Pfmrk
- Rho-associated protein kinase 1
- Rho-associated protein kinase 1 (ROCK I)
- Rho-associated protein kinase 2
- Rho-associated protein kinase 2 (ROCK II)
- Rho-associated protein kinase 2/Rho-kinase (ROCK I)
- Rho-kinase (ROCK II)
- Ribosomal protein S6 kinase alpha 5
- Serine/threonine-protein kinase 33
- cAMP-Dependent Protein Kinase (PKA)
- cAMP-Dependent Protein Kinase (PKA) Mutant (E127D)
- cAMP-Dependent Protein Kinase (PKA) Mutant (L49I)
- cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/Q181K/T183A)
- cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/V123M/E127D/Q181K/T183A)
- cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/V123M/Q181K/T183A)
- cAMP-Dependent Protein Kinase (PKA) Mutant (Q181K/T183A)
- cAMP-Dependent Protein Kinase (PKA) Mutant (T183A)
- cAMP-Dependent Protein Kinase (PKA) Mutant (V123M)
- cAMP-Dependent Protein Kinase (PKA) Mutant (V123M/Q181K/T183A)
- cAMP-Dependent Protein Kinase (PKA) Mutant (V123M/T183A)
- cAMP-dependent protein kinase (PKA)
- cGMP-dependent protein kinase
| - 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
- 5-(1,4-diazepane-1-sulfonyl)isoquinoline
- AT877
- CHEMBL38380
- CHEMBL541388
- Fasudil (HA-1077)
- HA-1077
- US9687483, Fasudil
- cid_163751
|
BDBM50005257
| 52 | 1 | 1 | 4 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)
- Dopamine D2 receptor and serotonin 2a receptor
- HTR1D
- Monoamine oxidase
- Serotonin (5-HT) receptor
- Serotonin 1 (5-HT1) receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor (2b and 2c)
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
| - (+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine
- (+)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine
- (+/-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine
- (-)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine
- (-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine
- 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine
- 2-(2-Methoxy-phenyl)-1-methyl-ethylamine
- 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine
- 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((-)-DOB)
- 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((R)-(-)-DOB)
- 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((S)-(+)-DOB)
- 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine(DOB)
- 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine[R(-)DOB]
- 2-(5-Bromo-2,4-dimethoxy-phenyl)-1-methyl-ethylamine
- Brolamfetamine
- CHEMBL6607
- DOB
- Racemic DOB
|
BDBM50056272
| 26 | 2 | 0 | 30 | 0 | 0 | 0 | 0 | - GRIA3
- GRM7
- GRM8
- Group II metabotropic glutamate receptor (mGlu2/mGlu3)
- Metabotropic glutamate receptor
- Metabotropic glutamate receptor 1
- Metabotropic glutamate receptor 2
- Metabotropic glutamate receptor 3
- Metabotropic glutamate receptor 3 (mGlu3)
- Metabotropic glutamate receptor 4 (mGlu4)
- Metabotropic glutamate receptor 4 (mGluR4)
- Metabotropic glutamate receptor 5
- Metabotropic glutamate receptor 6
| - (1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
- (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
- (2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
- 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
- 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY 354740)
- 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid(LY354740)
- CHEMBL8759
- LY-354740
- LY366563
|
BDBM50119368
| 12 | 18 | 0 | 28 | 0 | 0 | 0 | 0 | - Melanocortin receptor 2
- Melanocortin receptor 3
- Melanocortin receptor 3 (MC3R)
- Melanocortin receptor 4
- Melanocortin receptor 5
- Melanocortin receptor 5 (MC5R)
- Melanocyte-stimulating hormone receptor
| - (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
- (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-cyclohexyl-4-(3H-[1,2,4]triazol-1-ylmethyl)-piperidin-1-yl]-2-oxo-ethyl}-amide
- (R)-N-((R)-1-(4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
- 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
- 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
- CHEMBL339053
- THIQ
|
BDBM50333465
| 3 | 55 | 0 | 0 | 0 | 0 | 0 | 0 | - α-glucosidase
- Acidic alpha-glucosidase
- Alpha-glucosidase
- Alpha-glucosidase MAL12
- Alpha-glucosidase MAL62
- Lactase-glycosylceramidase
- Lysosomal alpha-glucosidase
- Maltase-glucoamylase
- Pancreatic alpha-amylase
- alpha-Amylase
- alpha-Glucosidase (α-Glucosidase)
- alpha-glucosidase (Gaa)
| - (2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol
- (2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol
- (2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol
- (3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol
- 5-{5-[3,4-Dihydroxy-6-methyl-5-(4,5,6-trihydroxy-3-hydroxymethyl-cyclohex-2-enylamino)-tetrahydro-pyran-2-yloxy]-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy}-6-hydroxymethyl-tetrahydro-pyran-2,3,4-triol
- ACARBOSE
- BAY-G 5421
- CHEMBL1566
- Glucobay
- Precose
- acarbose
|
BDBM81444
| 58 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - ADRA1A
- ADRA1B
- ADRA2C
- Adrenergic receptor alpha
- Adrenergic receptor alpha-2
- Alpha adrenergic receptor 1A and 1B
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Cerebral cortex alpha adrenergic receptor
- Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
- HTR1A
- Histamine H1 receptor
- Serotonin (5-HT) receptor
- adrenergic Alpha1
- adrenergic Alpha2
| - CAS_185453
- NSC_185453
- WB 4101
- WB-4101
|
BDBM82463
| 58 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - SSTR2
- SSTR3
- SSTR4
- SSTR5
- Somatostatin receptor type 1
- Somatostatin receptor type 2
- Somatostatin receptor type 3
- Somatostatin receptor type 4
- Somatostatin receptor type 5
| - Cyclo[L-Trp-D-Trp-L-Lys-L-Thr-L-Phe-(7-amino*heptanoyl-L-Phe-)]
- L-362,855
- L-362855
|
BDBM85473
| 58 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - 5-Hydroxytryptamine receptor 6 (5-HT6)
- 5-Hydroxytryptamine receptor 7 (5-HT7)
- 5-hydroxytryptamine receptor 1A (5-HT1A)
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 3A
- ADRB2
- Adrenergic alpha1B
- Adrenergic receptor beta
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2C adrenergic receptor
- CHRM5
- Calcium channel
- Cannabinoid receptor 1
- Cholinergic, Nicotinic Alpha3Beta2
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Dopamine D5 receptor
- Dopamine receptor
- Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)
- Glycosylasparaginase (GA)
- Histamine H1 receptor
- Histamine H2 Receptor
- Histamine H4 receptor
- Imidazoline I1
- Ionotropic glutamate receptor NMDA 1/2D
- Kappa-type opioid receptor
- Metabotropic glutamate receptor
- Metabotropic glutamate receptor 2
- Metabotropic glutamate receptor 4 (mGlu4)
- Metabotropic glutamate receptor 6 (mGlu6)
- Metabotropic glutamate receptor 8 (mGlu8)
- Monoamine transporters; serotonin & dopamine
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Neuronal acetylcholine receptor
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor; alpha2/beta2
- Oxytocin receptor
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
- Vasopressin V1b receptor
- Vasopressin V2 receptor (V2)
| - L-Cysteic acid, 8
- L-cysteic acid
|
BDBM86194
| 58 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - 5-Hydroxytryptamine receptor 6 (5-HT6)
- 5-Hydroxytryptamine receptor 7 (5-HT7)
- 5-hydroxytryptamine receptor 1A (5-HT1A)
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 3A
- ADRB2
- Adrenergic alpha1B
- Adrenergic receptor beta
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- CHRM5
- Calcium channel
- Cannabinoid receptor 1
- Cholinergic, Nicotinic Alpha3Beta2
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Dopamine D5 receptor
- Dopamine receptor
- Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)
- Histamine H1 receptor
- Histamine H2 Receptor
- Histamine H4 receptor
- Imidazoline I1
- Ionotropic glutamate receptor NMDA 1/2D
- Kappa-type opioid receptor
- Metabotropic glutamate receptor
- Metabotropic glutamate receptor 2
- Metabotropic glutamate receptor 4 (mGlu4)
- Metabotropic glutamate receptor 6 (mGlu6)
- Metabotropic glutamate receptor 8 (mGlu8)
- Monoamine transporters; serotonin & dopamine
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Neuronal acetylcholine receptor
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor; alpha2/beta2
- Oxytocin receptor
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
- Vasopressin V1b receptor
- Vasopressin V2 receptor (V2)
| - CAS_109
- L-cysteine sulfinic acid
- NSC_109
|
BDBM8726
| 24 | 33 | 1 | 0 | 0 | 0 | 0 | 0 | - Carbonyl reductase [NADPH] 1
- Enoyl-ACP Reductase (FabI)
- Enoyl-ACP Reductase (FabK)
- Enoyl-ACP Reductase (InhA)
- Enoyl-ACP Reductase (PfENR)
- Enoyl-ACP reductase (ENR)
- Enoyl-ACP reductase (FabI1)
- Enoyl-[acyl-carrier-protein] reductase [NADH]
- Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)
- Enoyl-acyl carrier reductase
- Enoyl-acyl-carrier protein reductase
- Transthyretin
| - 5-chloro-2-(2,4-dichlorophenoxy)phenol
- CHEMBL849
- TCL
- Triclosan
|