The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27923618 |
35 |
Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR. |
Integral Biosciences |
27512831 |
41 |
Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors. |
Pfizer |
27289323 |
2 |
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays. |
College Of Chemical And Environmental Engineering |
26769278 |
57 |
The Importance of Being Me: Magic Methyls, Methyltransferase Inhibitors, and the Discovery of Tazemetostat. |
Epizyme |
26189078 |
60 |
Discovery, design, and synthesis of indole-based EZH2 inhibitors. |
Constellation Pharmaceuticals |
25406853 |
72 |
Selective inhibitors of protein methyltransferases. |
Icahn School Of Medicine At Mount Sinai |
25746813 |
37 |
SAH derived potent and selective EZH2 inhibitors. |
Pfizer |
25699155 |
8 |
The role of enhancer of zeste homologue 2 inhibitors in controlling epigenetics and their potential for cancer treatment. |
Therachem Research Medilab (India) |
24767850 |
8 |
Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors. |
Korea Research Institute Of Chemical Technology |
24900844 |
50 |
Discovery and Optimization of Tetramethylpiperidinyl Benzamides as Inhibitors of EZH2. |
Constellation Pharmaceuticals |
24900432 |
51 |
Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2. |
TBA |
23488741 |
20 |
Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX. |
S.G.S.I.T.S. |
18702539 |
5 |
Thermodynamic and kinetic characterization of host-guest association between bolaform surfactants and alpha- and beta-cyclodextrins. |
Lund University |
18391212 |
4 |
Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation. |
Merck Research Laboratories |
16997559 |
29 |
5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase. |
Gsk |
17636950 |
41 |
Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors. |
University Of Mississippi |
15139750 |
4 |
Structure-based design and synthesis of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors. |
Fujisawa Pharmaceutical |
15828829 |
300 |
Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases. |
University Of Mississippi |
16620080 |
15 |
Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. |
Purdue University |
8632415 |
17 |
Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor. |
University Of Auckland |