The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27994728 |
23 |
Pyrazole Inhibitors of GluN2B NMDA Receptor Subunit. |
Dart Neuroscience |
27061977 |
8 |
Benzimidazolone bioisosteres of potent GluN2B selective NMDA receptor antagonists. |
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster |
25458498 |
29 |
Synthesis, GluN2B affinity and selectivity of benzo[7]annulen-7-amines. |
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster |
12639560 |
34 |
Novel N1-(benzyl)cinnamamidine derived NR2B subtype-selective NMDA receptor antagonists. |
Merck Sharp & Dohme Research Laboratories |
22366657 |
39 |
A novel series of benzimidazole NR2B-selective NMDA receptor antagonists. |
Glaxosmithkline |
18434149 |
23 |
Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors. |
University Of Strasburg |
11909726 |
36 |
5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. |
Novartis Pharma |
21524576 |
69 |
2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity. |
Astrazeneca Pharmaceuticals |
20965739 |
66 |
Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols. |
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster |
20875744 |
6 |
Synthesis and biological evaluation of radio-iodinated benzimidazoles as SPECT imaging agents for NR2B subtype of NMDA receptor. |
Hamamatsu University School Of Medicine |
20361801 |
100 |
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents. |
Friedrich-Schiller-Universitat Jena |
19648007 |
3 |
Synthesis and evaluation of novel tricyclic benzo[4.5]cyclohepta[1.2]pyridine derivatives as NMDA/NR2B antagonists. |
Merck Research Laboratories |
17498948 |
24 |
Cyclic benzamidines as orally efficacious NR2B-selective NMDA receptor antagonists. |
Merck Research Laboratories |
17249648 |
64 |
Identification and characterization of 4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an orally bioavailable, brain penetrant NR2B selective N-methyl-D-aspartate receptor antagonist. |
Merck Research Laboratories |
15225705 |
19 |
Oxamides as novel NR2B selective NMDA receptor antagonists. |
Gedeon Richter |
14552795 |
13 |
Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists. |
Gedeon Richter |
12639561 |
51 |
Orally efficacious NR2B-selective NMDA receptor antagonists. |
Merck Research Laboratories |
12519057 |
22 |
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity. |
Merck Research Laboratories |
10741546 |
66 |
Parallel synthesis of a series of subtype-selective NMDA receptor antagonists. |
Parke-Davis Pharmaceutical Research |
17761421 |
10 |
Identification of novel chemical inhibitors for ubiquitin C-terminal hydrolase-L3 by virtual screening. |
Waseda University |
15771420 |
58 |
Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4-[(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
11881999 |
123 |
Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors. |
Astrazeneca |