209 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28273563	59	Discovery of highly selective and potent monoamine oxidase B inhibitors: Contribution of additional phenyl rings introduced into 2-aryl-1,3,4-oxadiazin-5(6H)-one.	Seoul National University
28186757	66	Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.	European Institute Of Oncology
28186755	85	Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.	European Institute Of Oncology
28131710	22	DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-ß aggregation and monoamine oxidases with high antioxidant potency for Alzheimer's therapy.	Sichuan University
27951485	59	Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-ß-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease.	Sichuan University
28188065	9	Selective inhibition of monoamine oxidase A by purpurin, an anthraquinone.	Sunchon National University
28107736	53	Crystal structures, binding interactions, and ADME evaluation of brain penetrant N-substituted indazole-5-carboxamides as subnanomolar, selective monoamine oxidase B and dual MAO-A/B inhibitors.	Ntz Lab
28237559	65	Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases andß-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.	Sichuan University
2113950	1	Synthesis of (R)-(-)- and (S)-(+)-4-fluorodeprenyl and (R)-(-)- and (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl and positron emission tomography studies in baboon brain.	Brookhaven National Laboratory
4068012	3	1-Benzylcyclopropylamine and 1-(phenylcyclopropyl)methylamine: an inactivator and a substrate of monoamine oxidase.	TBA
28011206	36	Design, synthesis and biological evaluation of 4'-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease.	Sichuan University
27923535	39	Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.	Sichuan University
27908752	55	N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.	University Of Ljubljana
27692996	84	Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease.	China Pharmaceutical University
26471320	50	Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation.	Okayama University
27267007	58	New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties.	Instituto De Qu£Mica M£Dica
27578245	46	2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase.	North-West University
27135371	26	(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors.	Universit£
27079124	22	Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer's disease.	Sichuan University
26710088	248	Recent Progress in Histone Demethylase Inhibitors.	University Of Oxford
26819666	26	Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis.	Birla Institute Of Technology
26702542	59	Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.	European Institute Of Oncology
26974383	11	Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors.	Qatar University
26700437	32	Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators.	Kyoto Prefectural University Of Medicine
26964672	26	Novel tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one: Design, synthesis, model and use as hMAO-B inhibitors.	Anhui Medical University
26717204	17	Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold.	Universit£
26917219	63	Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.	China Pharmaceutical University
26821818	25	Inhibition of monoamine oxidase by benzoxathiolone analogues.	North-West University
26652247	60	3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.	Baylor College Of Medicine
26432037	14	Monoamine oxidase inhibitory activities of heterocyclic chalcones.	North-West University
26352677	44	Novel 2H-chromen-2-one derivatives of resveratrol: Design, synthesis, modeling and use as human monoamine oxidase inhibitors.	Hefei University Of Technology
26086931	38	Strategies for the Discovery of Target-Specific or Isoform-Selective Modulators.	Shandong University
26337020	69	Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors.	Korea Institute Of Science And Technology
26278660	90	Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders.	University Of Jena
25915162	12	New Frontiers in Selective Human MAO-B Inhibitors.	Sapienza University Of Rome
25934229	21	Synthesis and evaluation of selegiline derivatives as monoamine oxidase inhibitor, antioxidant and metal chelator against Alzheimer's disease.	Sun Yat-Sen University
26107513	172	Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases.	Universit£
25699146	13	Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies.	Sapienza University Of Rome
25812965	80	Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease.	China Pharmaceutical University
25768700	30	Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts.	Sapienza University Of Rome
25627172	150	Novel arylalkenylpropargylamines as neuroprotective, potent, and selective monoamine oxidase B inhibitors for the treatment of Parkinson's disease.	A* Star
25610955	53	Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.	Zhengzhou University
25418133	51	N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.	Laboratorio De Quimica Medica (Iqog, Csic)
25857942	30	The synthesis and evaluation of sesamol and benzodioxane derivatives as inhibitors of monoamine oxidase.	North-West University
25827526	33	Histone H3 peptide based LSD1-selective inhibitors.	Waseda University
25725609	18	Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.	John Hopkins University
25600407	26	Reversible and irreversible small molecule inhibitors of monoamine oxidase B (MAO-B) investigated by biophysical techniques.	Dart Neuroscience
25701250	32	Inhibition of monoamine oxidase by indole-5,6-dicarbonitrile derivatives.	Yaroslavl State Technical University
25542589	23	Multifunctional coumarin derivatives: monoamine oxidase B (MAO-B) inhibition, anti-ß-amyloid (Aß) aggregation and metal chelation properties against Alzheimer's disease.	China Pharmaceutical University
25541201	55	Design and synthesis of novel 2-pyrazoline-1-ethanone derivatives as selective MAO inhibitors.	Anhui Medical University
24986657	56	Synthesis of some novel hydrazone and 2-pyrazoline derivatives: monoamine oxidase inhibitory activities and docking studies.	Ministry Of Health Of Turkey
24955776	166	Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency.	University Of Bonn
25532905	10	Potent and selective MAO-B inhibitory activity: amino- versus nitro-3-arylcoumarin derivatives.	Universidad De Santiago De Compostela
25488845	4	Radiosynthesis and ex vivo evaluation of [(18)F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET.	University Of Toronto
25173853	50	Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.	European Institute Of Oncology
24904963	18	New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies.	Sapienza University Of Rome
24856304	25	New coumarin derivatives: design, synthesis and use as inhibitors of hMAO.	Anhui Medical University
24794105	38	a-Tetralone derivatives as inhibitors of monoamine oxidase.	North-West University
24793878	25	New 2H-chromene-3-carboxamide derivatives: design, synthesis and use as inhibitors of hMAO.	Anhui Medical University
24746464	29	Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors.	Sapienza University Of Rome
24187998	96	Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists.	University Of Copenhagen
23454517	56	A novel series of tacrine-selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease.	Sun Yat-Sen University
23211968	7	Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.	Karolinska Institutet
23207410	42	1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors.	Sapienza University Of Rome
23337801	24	Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema.	Astellas Pharma
23281824	118	Synthesis of (E)-8-(3-chlorostyryl)caffeine analogues leading to 9-deazaxanthine derivatives as dual A(2A) antagonists/MAO-B inhibitors.	Universit£
15203146	30	Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study.	Sapienza University Of Rome
12443774	12	Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies.	University Of Bari
22705191	45	Inhibition of monoamine oxidase by 8-phenoxymethylcaffeine derivatives.	North-West University
20934874	16	Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors.	Sapienza University Of Rome
17034132	122	Impact of species-dependent differences on screening, design, and development of MAO B inhibitors.	University Of Geneva
23122934	44	Inhibition of monoamine oxidase by 8-[(phenylethyl)sulfanyl]caffeine analogues.	North-West University
23122857	49	Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B.	North-West University
23102654	20	Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson's disease.	Northeast Ohio Medical University
22978824	17	Multitarget-directed benzylideneindanone derivatives: anti-ß-amyloid (Aß) aggregation, antioxidant, metal chelation, and monoamine oxidase B (MAO-B) inhibition properties against Alzheimer's disease.	Sun Yat-Sen University
23010267	23	Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B.	North-West University
23153812	68	Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.	Sapienza University Of Rome
22850212	30	Selected chromone derivatives as inhibitors of monoamine oxidase.	North-West University
22781190	102	Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B.	University Of Mississippi
22595173	68	The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).	Pharmaxis
22282722	10	Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs.	TBA
22436387	4	Synthesis and evaluation of [¹8F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).	Karolinska Institutet
21742494	44	Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B.	Northeastern Ohio Universities Colleges Of Medicine And Pharmacy
21726069	98	Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.	University Of Namur
21175212	3	Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex.	University Of Pavia
20875743	90	Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity rela	Pfizer
20708306	68	Synthesis of new series of quinoxaline based MAO-inhibitors and docking studies.	Alexandria University
20579890	111	Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.	Sapienza University Of Rome
20650633	12	Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.	Northeastern Ohio Universities
20123154	48	2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors.	University Of Chile
18272363	7	Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.	Johnson & Johnson Pharmaceutical Research & Development
18181565	71	Multi-target-directed ligands to combat neurodegenerative diseases.	University Of Bologna
16570912	24	Design, synthesis, and biological evaluation of semicarbazide-sensitive amine oxidase (SSAO) inhibitors with anti-inflammatory activity.	La Jolla Pharmaceutical
15537343	4	Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase.	Universit£T M£Nster
15056004	36	Synthesis and selective inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives against monoamine oxidase.	Sapienza University Of Rome
15027872	7	Fluorinated phenylcyclopropylamines. 1. Synthesis and effect of fluorine substitution at the cyclopropane ring on inhibition of microbial tyramine oxidase.	National Institute Of Diabetes And Digestive And Kidney Diseases
2296014	42	Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines.	University Of Texas
22264472	30	Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.	University Of Mississippi
22309913	30	Inhibition of monoamine oxidase by selected C6-substituted chromone derivatives.	North-West University
22225638	18	A scaffold hopping approach to identify novel monoamine oxidase B inhibitors.	Northeast Ohio Medical University
22078410	31	Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines.	West Virginia University
21955276	60	Lysine demethylases inhibitors.	Kyoto Prefectural University Of Medicine
22222137	13	Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.	Universit£
22137786	9	Hydroxycoumarins as selective MAO-B inhibitors.	Universit£
22071524	7	Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO.	Federal University Of Rio De Janeiro
22055712	33	Thio- and aminocaffeine analogues as inhibitors of human monoamine oxidase.	North-West University
22018876	4	Synthesis and inhibition study of monoamine oxidase, indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by 3,8-substituted 5H-indeno[1,2-c]pyridazin-5-one derivatives.	Facult£S Universitaires Notre-Dame De Paix
22005185	25	2D MI-DRAGON: a new predictor for protein-ligands interactions and theoretic-experimental studies of US FDA drug-target network, oxoisoaporphine inhibitors for MAO-A and human parasite proteins.	University Of Santiago De Compostela
21923198	6	Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).	Karolinska Institutet
21923181	28	Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors.	University Of Santiago De Compostela
21899930	37	Monoamine oxidase inhibition by selected anilide derivatives.	North-West University
21872365	54	Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives.	Sapienza University Of Rome
21777011	15	3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B.	University Of Cagliari
21778064	40	Inhibition of monoamine oxidase by C5-substituted phthalimide analogues.	North-West University
21696156	23	Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.	Universidade Do Porto
21621312	58	8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase.	North-West University
21684743	12	MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins.	Universidad De Santiago De Compostela
21680183	48	Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies.	Birla Institute Of Technology
19423346	8	A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.	Facultad De Farmacia
21405131	39	Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties.	Sapienza University Of Rome
21377879	44	Development of selective and reversible pyrazoline based MAO-B inhibitors: virtual screening, synthesis and biological evaluation.	Birla Institute Of Technology
21316817	14	Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives.	Universita Degli Studi Di Cagliari
21134756	90	Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues.	North-West University
21194943	9	Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors.	Universidade Do Porto
21183355	18	Synthesis and evaluation ofß-carboline derivatives as potential monoamine oxidase inhibitors.	Facult£S Universitaires Notre-Dame De La Paix
20843688	8	'Click' assembly of selective inhibitors for MAO-A.	Zhejiang University
20702005	17	Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.	Dipartimento Farmaco Chimico Tecnologico
20674099	48	Inhibition of monoamine oxidase by indole and benzofuran derivatives.	North-West University
20715818	78	Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines.	Sapienza University Of Rome
20659799	10	New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors.	Universidad De Santiago De Compostela
20615716	55	Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.	Sapienza University Of Rome
20382016	8	Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.	Universit£
19926363	29	Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.	Universit£
20045650	56	A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.	Sapienza University Of Rome
20093036	28	Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues.	North-West University
19628387	6	Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors.	Universidad De Santiago De Compostela
19321235	22	Knowledge based identification of MAO-B selective inhibitors using pharmacophore and structure based virtual screening models.	Gvk Biosciences
	52	Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidase	TBA
19342233	12	Inhibition of monoamine oxidase by (E)-styrylisatin analogues.	North-West University
19064321	37	Ultrasound promoted synthesis of 2-imidazolines in water: a greener approach toward monoamine oxidase inhibitors.	Universidade Federal De Santa Maria
19053775	4	Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.	Emory University
18834112	52	Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.	University Of Santiago De Compostela
18723354	12	Dual inhibition of monoamine oxidase B and antagonism of the adenosine A(2A) receptor by (E,E)-8-(4-phenylbutadien-1-yl)caffeine analogues.	North-West University
18666768	39	Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.	Sapienza University Of Rome
18640844	38	Fluorinated phenylcyclopropylamines. Part 5: Effects of electron-withdrawing or -donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines.	UniversitäT MüNster
17521909	15	Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies.	University Of Santiago De Chile
16137882	10	Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds.	Kadir Has University
15974574	56	Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors.	Sapienza University Of Rome
14698188	13	Fentanyl derivatives bearing aliphatic alkaneguanidinium moieties: a new series of hybrid molecules with significant binding affinity for mu-opioid receptors and I2-imidazoline binding sites.	Instituto De QuíMica MéDica
12540239	3	Indanylidenes. 1. Design and synthesis of (E)-2-(4,6-difluoro-1-indanylidene)acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and analgesic activity.	Glaxosmithkline
12467619	12	Rational approaches towards reversible inhibition of type B monoamine oxidase. Design and evaluation of a novel 5H-Indeno[1,2-c]pyridazin-5-one derivative.	FacultéS Universitaires Notre-Dame De La Paix
12443791	14	Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.	Sapienza University Of Rome
3260955	14	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues. Inactivation of monoamine oxidase by conformationally rigid analogues of N,N-dimethylcinnamylamine.	Northwestern University
29316397	47	Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists.	Bristol-Myers Squibb
28537720	5	Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances.	University Of Porto
21985377	42	Synthesis and biological evaluation of novel N, N'-disubstituted urea and thiourea derivatives as potential anti-melanoma agents.	Nanjing University
21815772	22	Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds.	Artvin Coruh University
20030512	1	New antihyperglycemic, alpha-glucosidase inhibitory, and cytotoxic derivatives of benzimidazoles.	Indian Institute Of Chemical Technology
28525735	2	Structure-based rational design of self-inhibitory peptides to disrupt the intermolecular interaction between the troponin subunits C and I in neuropathic pain.	The Affiliated Hospital Of Qingdao University
28481076	7	Heme Proximal Hydrogen Bonding between His170 and Asp132 Plays an Essential Role in the Heme Degradation Reaction of HutZ from Vibrio cholerae.	Hokkaido University
28387506	3	Interaction of Azole-Based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: A Molecular Basis for Toxicity.	North Carolina State University
14500740	13	Differential activation of formyl peptide receptor signaling by peptide ligands.	Pohang University Of Science And Technology
8813598	34	Affinity of various ligands for GABAA receptors containing alpha 4 beta 3 gamma 2, alpha 4 gamma 2, or alpha 1 beta 3 gamma 2 subunits.	University Clinic For Psychiatry
8788493	64	Novel discriminatory ligands for 5-HT2B receptors.	Smithkline Beecham Pharmaceuticals
19113826	12	Rigid duplex alpha-cyclodextrin reversibly connected with disulfide bonds. Synthesis and inclusion complexes.	Institute Of Organic Chemistry And Biochemistry As Cr
17416521	67	Discovery and structure-activity relationship studies of indole derivatives as liver X receptor (LXR) agonists.	Tanabe Research Laboratories Usa
19143565	58	Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein kinases.	University Of Tartu
19128055	24	Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.	Universite De Lyon
18790643	42	A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis.	University Of Wisconsin-Milwaukee
18578471	16	Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.	Astrazeneca
12951118	24	HIV-1 protease inhibitors with picomolar potency against PI-resistant HIV-1 by modification of the P1' substituent.	Merck Research Laboratories
12941332	27	6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).	Glaxosmithkline
12941338	18	Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2.	University Of Newcastle
12646019	48	Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase.	Sugen
2552117	68	Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors.	Hebrew University Of Jerusalem
18589438	10	Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1.	University Of Otago
8523406	59	Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studies of PETT analogs.	Eli Lilly
1588552	30	HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activity.	Merck Research Laboratories