The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26947959 |
35 |
Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors. |
University Of Pardubice |
26632651 |
70 |
Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography. |
China Pharmaceutical University |
26363872 |
19 |
Synthesis and structure-activity relationship study of benzofuran-based chalconoids bearing benzylpyridinium moiety as potent acetylcholinesterase inhibitors. |
Alzahra University |
26260334 |
28 |
Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity. |
Medical University Of Sofia |
25017625 |
45 |
Synthesis and cholinesterase inhibition of cativic acid derivatives. |
Universidad Nacional Del Sur |
24835788 |
28 |
Preparation, anticholinesterase activity and molecular docking of new lupane derivatives. |
Universidad Nacional Del Sur |
18538575 |
3 |
Petrosamine, a potent anticholinesterase pyridoacridine alkaloid from a Thai marine sponge Petrosia n. sp. |
Mahidol University |
18479118 |
114 |
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors. |
Universit£ |
17944454 |
34 |
First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor. |
University Of Bonn |
15139762 |
133 |
Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship. |
University Of Hamburg |
10052979 |
45 |
Aminopyridazines as acetylcholinesterase inhibitors. |
Universit£ |
8978837 |
60 |
Structure-based alignment and comparative molecular field analysis of acetylcholinesterase inhibitors. |
University Of North Carolina |
8893840 |
12 |
The simulated binding of (+/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]meth yl] -1H-inden-1-one hydrochloride (E2020) and related inhibitors to free and acylated acetylcholinesterases and corresponding structure-activity analyses. |
Eisai |
19726199 |
30 |
Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives. |
The Chinese Academy Of Sciences |
| 5 |
m-Alkyl, α,α,α-trifluoroacetophenones: A new class of potent transition state analog inhibitors of acetylcholinesterase |
TBA |
17317172 |
9 |
Methyl 2-(2-(4-formylphenoxy)acetamido)-2-substituted acetate derivatives: a new class of acetylcholinesterase inhibitors. |
Sun Yat-Sen University |
14584959 |
55 |
Molecular docking studies of natural cholinesterase-inhibiting steroidal alkaloids from Sarcococca saligna. |
University Of Innsbruck |
12729674 |
6 |
Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives. |
Instituto PolitéCnico Nacional |
9871563 |
31 |
Synthesis and activity studies of N-[omega-N'-(adamant-1'-yl)aminoalkyl]- 2-(4'-dimethylaminophenyl)acetamides: in the search of selective inhibitors for the different molecular forms of acetylcholinesterase. |
Istituto Di Strutturistica Chimica G. Giacomello |
26322521 |
6 |
Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. |
The University Of Kansas Medical Center |
18849971 |
56 |
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. |
University Of California San Francisco |
18942826 |
19 |
Inhibitor Scaffolds for 2-Oxoglutarate-Dependent Histone Lysine Demethylases. |
University Of Oxford |
18227510 |
8 |
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. |
Harvard Medical School |
17846131 |
15 |
Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography. |
University Of California San Francisco |
18473434 |
57 |
Novel inhibitors of the v-raf murine sarcoma viral oncogene homologue B1 (BRAF) based on a 2,6-disubstituted pyrazine scaffold. |
Cancer Research Uk Centre For Cancer Therapeutics |
18925736 |
19 |
Structure-activity relationship studies of phenanthridine-based Bcl-XL inhibitors. |
A* Star |
18793847 |
33 |
Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors. |
Sunesis Pharmaceuticals |