The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28658574 |
124 |
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold To Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII. |
Universit£ |
| 28272885 |
126 |
Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action. |
Universit£ |
| 28253618 |
104 |
Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. |
University Of Delhi |
| 28256371 |
83 |
Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects. |
University Of Wollongong |
| 28161252 |
64 |
Synthesis and biological evaluation of cyclic imides incorporating benzenesulfonamide moieties as carbonic anhydrase I, II, IV and IX inhibitors. |
King Saud University |
| 28025002 |
80 |
Sulfonamide inhibition profile of the¿-carbonic anhydrase identified in the genome of the pathogenic bacterium Burkholderia pseudomallei the etiological agent responsible of melioidosis. |
Istituto Di Bioscienze E Biorisorse |
| 25432060 |
92 |
Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties. |
Atat£Rk University |
| 28238511 |
36 |
Comparison of the anion inhibition profiles of theß- and¿-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei. |
Istituto Di Bioscienze E Biorisorse, Cnr |
| 28237553 |
76 |
Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds. |
Saint Petersburg State University |
| 28109946 |
84 |
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies. |
Kafrelsheikh University |
| 28075587 |
102 |
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis. |
University Of Florence |
| 27823879 |
88 |
New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs. |
Maastricht University Medical Centre |
| 1635066 |
17 |
Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity. |
Istituto Chimico Internazionale Dr. G. Rende |
| 3735316 |
8 |
N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure. |
TBA |
| 12565948 |
120 |
Modelling of carbonic anhydrase inhibitory activity of sulfonamides using molecular negentropy. |
A.P.S. University |
| 28111158 |
100 |
Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties. |
Abant Izzet Baysal University |
| 28065499 |
84 |
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors. |
Kurukshetra University |
| 27919611 |
60 |
Discovery of 4-sulfamoyl-phenyl-ß-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors. |
National Institute Of Pharmaceutical Education And Research (Niper) |
| 28057408 |
44 |
Dithiocarbamates effectively inhibit theß-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa. |
Universit£ |
| 28024887 |
52 |
5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations. |
Riga Technical University |
| 27939347 |
52 |
Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity. |
Universit£ |
| 27876475 |
68 |
Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII. |
Dumlupinar University |
| 27884694 |
16 |
Synthesis and carbonic anhydrase inhibitory properties of novel chalcone substituted benzenesulfonamides. |
Giresun University |
| 27933963 |
60 |
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. |
Universit£ |
| 27396930 |
48 |
Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties. |
Universit£ |
| 27469982 |
6 |
Bortezomib inhibits bacterial and fungalß-carbonic anhydrases. |
Universit£ |
| 27144971 |
60 |
PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas. |
Temple University |
| 27172398 |
20 |
An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C. |
Griffith University |
| 27316543 |
24 |
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors. |
Universit£ |
| 27298005 |
92 |
Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII. |
Dumlupinar University |
| 27234893 |
36 |
Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines. |
Cairo University |
| 27166574 |
52 |
Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII. |
Kurukshetra University |
| 27137360 |
100 |
Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII. |
Kurukshetra University |
| 26805033 |
426 |
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII. |
Uppsala University |
| 27068142 |
79 |
Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds. |
Erzurum Technical University |
| 26972117 |
48 |
Comparison of the sulfonamide inhibition profiles of thea-,ß- and¿-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae. |
Universit£ |
| 26951893 |
96 |
Isatin analogs as novel inhibitors of Candida spp.ß-carbonic anhydrase enzymes. |
Bezmialem Vakif University |
| 26920803 |
80 |
Sulfonamide inhibition studies of theß-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13. |
Recep Tayyip Erdogan University |
| 26875933 |
72 |
Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma. |
Dais |
| 26853167 |
52 |
Anion inhibition studies of theß-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
Universit£ |
| 26840366 |
72 |
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII. |
Egyptian Russian University |
| 26832216 |
41 |
Sulfonamide inhibition studies of the¿-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea. |
Universit£ |
| 26741028 |
100 |
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. |
Universit£ |
| 26850377 |
80 |
Sulfonamide inhibition studies of theß-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
Universit£ |
| 26810836 |
28 |
Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111. |
University Of Florida College Of Medicine |
| 26810710 |
116 |
A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms. |
University Of Chieti-Pescara |
| 26804228 |
28 |
Pyridazinone substituted benzenesulfonamides as potent carbonic anhydrase inhibitors. |
Jamia Hamdard (Hamdard University) |
| 26688270 |
104 |
Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins. |
Universit£ |
| 26803577 |
92 |
Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII. |
Harran University |
| 26611920 |
50 |
Optimization of allosteric MEK inhibitors. Part 2: Taming the sulfamide group balances compound distribution properties. |
Bayer Healthcare |
| 26691758 |
160 |
Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. |
Universit£ |
| 26520662 |
45 |
Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives. |
Balikesir University |
| 26497049 |
110 |
Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. |
Sapienza University Of Rome |
| 26498394 |
105 |
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters. |
Universit£ |
| 26408817 |
69 |
Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII. |
Egyptian Russian University |
| 26534780 |
22 |
Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives. |
Gebze Technical University |
| 26498393 |
116 |
New natural product carbonic anhydrase inhibitors incorporating phenol moieties. |
Aristotle University Of Thessaloniki |
| 26432607 |
60 |
Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII. |
Universit£ |
| 26422787 |
68 |
Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII. |
Dumlupinar University |
| 25998503 |
12 |
Activity and anion inhibition studies of thea-carbonic anhydrase from Thiomicrospira crunogena XCL-2 Gammaproteobacterium. |
University Of Florida |
| 26347950 |
32 |
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases. |
Griffith University |
| 26319622 |
12 |
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents. |
Universit£ |
| 26276436 |
45 |
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. |
Universit£ |
| 26233435 |
76 |
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity. |
University Of Cagliari |
| 26264840 |
104 |
Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies. |
University Of Chieti-Pescara |
| 26160114 |
101 |
Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms. |
Saint Petersburg State University |
| 26191373 |
52 |
Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series. |
Institute Of Biomolecules Max Mousseron (Ibmm) |
| 26174556 |
41 |
Sulfonamide inhibition studies of the¿-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
Universit£ |
| 26233796 |
68 |
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties. |
University Of Cagliari |
| 26203869 |
18 |
Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates. |
University Of Florida |
| 26105196 |
52 |
Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. |
Kurukshetra University |
| 26073006 |
56 |
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII. |
University Of Cagliari |
| 26073005 |
18 |
Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives. |
Agriibrahim£E£En University |
| 26068018 |
76 |
Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa. |
University Of Florida |
| 25168748 |
37 |
Anion inhibition study of theß-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis. |
Universit£ |
| 25168745 |
64 |
Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the¿-carbonic anhydrases. |
Istituto Di Bioscienze E Biorisorse (Ibbr)-Cnr |
| 26145820 |
47 |
Cloning, characterization and anion inhibition studies of a new¿-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis. |
Istituto Di Bioscienze E Biorisorse |
| 26048024 |
84 |
Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. |
Jazan University |
| 26088336 |
96 |
5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII. |
University Of Belgrade |
| 25921269 |
45 |
Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: novel sulfamoylcarbamates and sulfamides derived from acetophenones. |
Agriibrahim£E£En University |
| 25921266 |
48 |
New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors. |
Siedlce University Of Natural Sciences And Humanities |
| 26007302 |
56 |
New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies. |
University Of Chieti-Pescara |
| 25875209 |
60 |
6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells. |
Latvian Institute Of Organic Synthesis |
| 25913118 |
95 |
Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII. |
Harran University |
| 25912674 |
52 |
Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives. |
Cairo University |
| 25581127 |
14 |
Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site. |
Griffith University |
| 25553540 |
6 |
1,3,4-Thiadiazoles: a potent multi targeted pharmacological scaffold. |
University Of Mississippi |
| 25882523 |
120 |
Theß-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. |
University Of Tampere And Tampere University Hospital |
| 25863492 |
44 |
N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II. |
Atat£Rk University |
| 25846066 |
88 |
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action. |
Universit£ |
| 25773015 |
80 |
Sulfonamide inhibition studies of the¿-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. |
Universit£ |
| 25766630 |
100 |
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. |
Universit£ |
| 25757603 |
79 |
New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity. |
Siedlce University Of Natural Sciences And Humanities |
| 25753329 |
56 |
Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action. |
Latvian Institute Of Organic Synthesis |
| 25533402 |
76 |
Sulfonamide inhibition studies of the¿-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum. |
Universit£ |
| 25147616 |
92 |
Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry. |
Universit£ |
| 25129169 |
80 |
Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: theß-class (PgiCAb) versus the¿-class (PgiCA) enzymes. |
Istituto Di Biochimica Delle Proteine-Cnr |
| 25050173 |
42 |
Sulfonamides with Potent Inhibitory Action and Selectivity against thea-Carbonic Anhydrase from Vibrio cholerae. |
Universit£ |
| 25050167 |
40 |
Carbonic anhydrase inhibitors: design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives. |
Bharati Vidyapeeth'S College Of Pharmacy |
| 25027802 |
56 |
Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies. |
Sapienza University Of Rome |
| 25022971 |
124 |
Furazan and furoxan sulfonamides are stronga-carbonic anhydrase inhibitors and potential antiglaucoma agents. |
Universit£ |
| 25019479 |
96 |
Cyclic tertiary sulfamates: selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives. |
Sapienza University Of Rome |
| 25011913 |
42 |
Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis¿-carbonic anhydrase. |
Universit£ |
| 24948563 |
44 |
Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors. |
University Of Perugia |
| 25468040 |
77 |
Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV. |
TBA |
| 25456084 |
100 |
4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII. |
Kurukshetra University |
| 25442309 |
120 |
Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds. |
King Saud University |
| 25438758 |
44 |
Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: towards new carbonic anhydrase glycoinhibitors. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 25358084 |
143 |
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. |
Vilnius University |
| 25358036 |
64 |
A class of 4-sulfamoylphenyl-¿-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects. |
Universit£ |
| 25310626 |
80 |
Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups. |
Universit£ |
| 25267005 |
70 |
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones. |
Universit£ |
| 25255434 |
84 |
Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling. |
King Saud University |
| 25254302 |
44 |
Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates. |
Griffith University |
| 25245672 |
5 |
Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis,ß-glucuronidase inhibition activity, crystal structure, and POM analyses. |
King Saud University |
| 25194929 |
28 |
Quinazoline-sulfonamides with potent inhibitory activity against thea-carbonic anhydrase from Vibrio cholerae. |
Salman Bin Abdulaziz University |
| 25156300 |
48 |
Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. |
Universidad Nacional De La Plata |
| 24878360 |
76 |
Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties. |
King Saud University |
| 24871996 |
124 |
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII. |
Medical University Of Gdansk |
| 24856184 |
24 |
Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives. |
Agriibrahim£E£En University |
| 24813742 |
98 |
Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors. |
Universit£ |
| 24792813 |
80 |
Sulfonamide inhibition studies of twoß-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. |
Kochi Medical School |
| 24746465 |
90 |
Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties. |
Enscm/Umii/Umr-Cnrs 5635 |
| 24713308 |
48 |
Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity. |
Siedlce University Of Natural Sciences And Humanities |
| 24589511 |
60 |
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties. |
University Of Cagliari |
| 24689792 |
54 |
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes. |
Griffith University |
| 24650641 |
110 |
Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII. |
Universit£ |
| 23664215 |
45 |
Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening. |
East China University Of Science And Technology |
| 23647428 |
84 |
Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo. |
Universit£ |
| 22883029 |
80 |
The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides. |
Universit£ |
| 23490152 |
15 |
Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition. |
University Of Florida |
| 23429054 |
48 |
Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship. |
East China University Of Science And Technology |
| 23414807 |
70 |
Anion inhibition studies of thea-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
Universit£ |
| 23414801 |
38 |
Kinetic and anion inhibition studies of aß-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis. |
Istituto Di Biostrutture E Bioimmagini |
| 23394864 |
16 |
Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors. |
Atat£Rk University |
| 23394791 |
177 |
4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. |
Vilnius University Institute Of Biotechnology |
| 23352754 |
28 |
o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII. |
Istanbul University |
| 23290254 |
92 |
Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII. |
Salman Bin Abdulaziz University |
| 23266178 |
115 |
Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV. |
National University Of La Plata |
| 23206986 |
259 |
QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII. |
Romanian Academy |
| 23199483 |
25 |
Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 23168081 |
72 |
New selective carbonic anhydrase IX inhibitors: synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides. |
University Of Lille |
| 23121721 |
6 |
Synthesis of 1,4-bis(indolin-1-ylmethyl)benzene derivatives and their structure-activity relationships for the interaction of human carbonic anhydrase isoforms I and II. |
Karamanoglu Mehmetbey University |
| 23018095 |
36 |
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors. |
Universit£ |
| 23010455 |
108 |
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases. |
Universidad Nacional De La Plata |
| 22974493 |
13 |
Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity. |
Agri Ibrahim Cecen University |
| 22892213 |
168 |
Natural product coumarins that inhibit human carbonic anhydrases. |
Griffith University |
| 22705188 |
73 |
Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: new selective tumor-associated carbonic anhydrase inhibitors. |
Superacide Et Chimie Des Syst£Mes£ |
| 22668600 |
200 |
Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. |
Universit£ |
| 23391336 |
80 |
Cloning, characterization, and sulfonamide and thiol inhibition studies of ana-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease. |
University Of Tampere And Tampere University Hospital |
| 23265898 |
20 |
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors. |
Universit£ |
| 23241068 |
84 |
Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases. |
Latvian Association Of Human Genetics |
| 23218470 |
24 |
Facile synthesis and characterization of novel pyrazole-sulfonamides and their inhibition effects on human carbonic anhydrase isoenzymes. |
Dumlupinar University |
| 23200251 |
44 |
Restoring catalytic activity to the human carbonic anhydrase (CA) related proteins VIII, X and XI affords isoforms with high catalytic efficiency and susceptibility to anion inhibition. |
Kochi Medical School |
| 23072866 |
72 |
Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense. |
Universit£ |
| 22910138 |
96 |
Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII. |
TBA |
| 23181552 |
10 |
DNA cloning, characterization, and inhibition studies of ana-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. |
Istituto Di Biochimica Delle Proteine-Cnr |
| 23067387 |
105 |
Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms. |
Universit£ |
| 22894736 |
99 |
Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment. |
The Hebrew University Of Jerusalem |
| 22775345 |
74 |
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 22621623 |
44 |
Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts. |
University Of Manchester |
| 22901388 |
76 |
Inhibition ofa-class cytosolic human carbonic anhydrases I, II, IX and XII, andß-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors. |
Universit£ |
| 22721713 |
200 |
Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 22443141 |
115 |
Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors. |
Universit£ |
| 22424239 |
42 |
Molecular cloning, characterization, and inhibition studies of aß-carbonic anhydrase from Malassezia globosa, a potential antidandruff target. |
Union Life Sciences |
| 22687439 |
51 |
Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B. |
Atat£Rk University |
| 22276570 |
112 |
Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo. |
Universit£ |
| 22487176 |
109 |
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins. |
Universit£ |
| 22440859 |
176 |
Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. |
Vilnius University |
| 21211980 |
47 |
Characterization and anions inhibition studies of ana-carbonic anhydrase from the teleost fish Dicentrarchus labrax. |
Ondokuz Mayis University |
| 20580561 |
33 |
Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity. |
Instituto Superior T£Cnico |
| 20674354 |
79 |
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV. |
Universit£ |
| 20605094 |
91 |
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
University Of Florida |
| 20598552 |
24 |
Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations. |
University Of Florida |
| 20478708 |
28 |
New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors. |
Lneg |
| 20472429 |
80 |
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 20201556 |
174 |
Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases. |
Griffith University |
| 19388676 |
21 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies. |
Johnson & Johnson Pharmaceutical Research & Development |
| 20006931 |
18 |
Synthesis, characterization and antiglaucoma activity of a novel proton transfer compound and a mixed-ligand Zn(II) complex. |
Dumlupinar University |
| 20185318 |
132 |
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. |
Universit£ |
| 19911821 |
273 |
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. |
Universita Degli Studi Di Firenze |
| 19854054 |
18 |
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma. |
Nicox Research Institute |
| 20028100 |
78 |
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. |
Universit£ |
| 19846301 |
75 |
Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c. |
Universit£ |
| 19827837 |
52 |
S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases. |
Griffith University |
| 19520577 |
111 |
Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. |
Centre Scientifique De Monaco |
| 19398204 |
44 |
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides. |
Universit£ |
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75 |
Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties. |
Griffith University |
| 19269822 |
75 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. |
Universit£ |
| 19186056 |
60 |
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases. |
Universit£ |
| 19124253 |
111 |
Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. |
Balikesir University |
| 18990571 |
65 |
Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 18644716 |
52 |
Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives. |
Griffith University |
| 18513964 |
45 |
Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes. |
Universit£ |
| 18501600 |
33 |
Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols. |
Universit£ |
| 18359629 |
84 |
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 18042384 |
60 |
Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 18307288 |
70 |
Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides. |
Griffith University |
| 17475500 |
130 |
Carbonic anhydrases as targets for medicinal chemistry. |
Universit£ |
| 17826101 |
41 |
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. |
Kochi Medical School |
| 17681760 |
21 |
Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety. |
Griffith University |
| 17376683 |
63 |
Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 17314045 |
11 |
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I. |
Universit£ |
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95 |
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates. |
Universit£ |
| 17228881 |
141 |
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
Kochi Medical School |
| 16459077 |
105 |
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. |
Kochi Medical School |
| 16290146 |
30 |
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II"selective" inhibitor celecoxib. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 16203142 |
55 |
Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides. |
Universit£ |
| 16220969 |
219 |
Designed multiple ligands. An emerging drug discovery paradigm. |
Organon Laboratories |
| 15456265 |
52 |
Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library. |
University Of Florence |
| 15837324 |
30 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors. |
Universit£ |
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112 |
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. |
Universit£ |
| 15686894 |
101 |
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
Universit£ |
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84 |
Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. |
Universit£ |
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65 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates. |
Universit£ |
| 15664814 |
55 |
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate. |
Universit£ |
| 15603956 |
63 |
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX. |
Harran University |
| 16039848 |
93 |
Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
Kochi Medical School |
| 16039853 |
89 |
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma. |
Universita Degli Studi |
| 15905091 |
134 |
Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX. |
Universit£ |
| 15546717 |
130 |
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides. |
Pennsylvania State University |
| 15501040 |
26 |
Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties. |
Universit£ |
| 15501039 |
51 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide. |
Universit£ |
| 15501038 |
68 |
Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions. |
Universit£ |
| 15454240 |
57 |
Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. |
Universit£ |
| 15454239 |
74 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties. |
Universit£ |
| 15357993 |
82 |
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions. |
Universit£ |
| 15139757 |
105 |
Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity. |
Universit£ |
| 12747791 |
91 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors. |
University Of Montpellier |
| 11906288 |
713 |
Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties. |
Universit£ |
| 11784136 |
100 |
Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. |
University Of Namur |
| 12166931 |
13 |
Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design. |
Universit£ |
| 11123998 |
141 |
Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects. |
Universit£ |
| 11087579 |
465 |
Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged duration of action. |
Universit£ |
| 10479300 |
383 |
Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route. |
Universit£ |
| 10411484 |
176 |
Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? |
Universit£ |
| 15012984 |
192 |
Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX. |
Slovak Academy Of Sciences |
| 15081039 |
68 |
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered. |
Universit£ |
| 14698154 |
26 |
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. |
Bruker-Axs |
| 15203157 |
68 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design. |
University Of Tampere |
| 14684333 |
9 |
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase. |
Universit£ |
| 14684332 |
27 |
Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits. |
University Of Montpellier |
| 14684331 |
24 |
Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. |
Universit£ |
| 12643899 |
127 |
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. |
Universit£ |
| 12617904 |
46 |
Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV. |
Universit£ |
| 12617903 |
65 |
Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives. |
Universit£ |
| 14611846 |
101 |
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide. |
Universit£ |
| 12039560 |
377 |
Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails. |
Universit£ |
| 11229775 |
204 |
Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. |
Universit£ |
| 11425561 |
197 |
Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties. |
Universit£ |
| 10762051 |
66 |
Carbonic anhydrase inhibitors: topical sulfonamide antiglaucoma agents incorporating secondary amine moieties. |
Universit£ |
| 10843231 |
129 |
Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV. |
Universit£ |
| 22377674 |
80 |
Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII. |
Universit£ |
| 22370338 |
183 |
Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases. |
Griffith University |
| 22365761 |
144 |
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. |
Universit£ |
| 22227210 |
74 |
Anion inhibition studies of ana-carbonic anhydrase from the living fossil Astrosclera willeyana. |
Slovak Academy Of Sciences |
| 22285172 |
124 |
Cloning, characterization and sulfonamide inhibition studies of ana-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. |
Slovak Academy Of Sciences |
| 22245047 |
135 |
Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI. |
Ondokuz Mayis University |
| 22230050 |
82 |
Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives. |
Artvin£Oruh University |
| 22077347 |
44 |
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 22137345 |
36 |
5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors. |
Universit£ |
| 22041171 |
44 |
Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors. |
Universit£ |
| 21852133 |
68 |
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II. |
University Of Alberta |
| 21851094 |
92 |
Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors. |
Griffith University |
| 21821413 |
65 |
Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 21820216 |
75 |
Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives. |
Medical University Of Gdansk |
| 21757360 |
86 |
Inhibition studies of theß-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. |
Kochi Medical School |
| 21515057 |
153 |
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies. |
Universit£ |
| 21723123 |
48 |
N-ß-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. |
Universidad Nacional De La Plata |
| 21669522 |
23 |
In vitro inhibition ofa-carbonic anhydrase isozymes by some phenolic compounds. |
Gumushane University |
| 21620713 |
25 |
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. |
University Of Florida |
| 21470859 |
52 |
Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 19435663 |
63 |
Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors. |
Istanbul University |
| 21506569 |
96 |
Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV. |
The Hebrew University Of Jerusalem |
| 21570835 |
78 |
Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium. |
Universit£ |
| 21549597 |
71 |
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. |
U.O. Oculistica Az. Usl 3 |
| 21420862 |
4 |
Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore. |
Universit£ |
| 21402476 |
79 |
Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives. |
Universit£ |
| 21377369 |
60 |
Purification and inhibition studies with anions and sulfonamides of ana-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii. |
Universit£ |
| 21361354 |
112 |
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis. |
Universita` Degli Studi Di Firenze |
| 21332115 |
162 |
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases. |
Griffith University |
| 21314129 |
76 |
Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors. |
Griffith University |
| 21300547 |
64 |
(R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases. |
Universit£ |
| 21251841 |
90 |
A newß-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
University Of Montpellier |
| 21282059 |
48 |
Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. |
University Of Calgary |
| 21208801 |
275 |
Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. |
Centre Scientifique De Monaco |
| 21163660 |
31 |
Inhibition of theß-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives? |
Radboud University Nijmegen Medical Centre |
| 21067924 |
88 |
7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range. |
Università |
| 20724038 |
78 |
Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide. |
Dumlupinar University |
| 20926301 |
77 |
Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII. |
Institute Of Biotechnology |
| 20889345 |
94 |
4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII. |
Vilnius University |
| 20880712 |
69 |
Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors. |
University Of Lille |
| 20833546 |
6 |
Paraoxon, 4-nitrophenyl phosphate and acetate are substrates ofa- but not ofß-,¿- and¿-carbonic anhydrases. |
Università |
| 20554082 |
76 |
Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII. |
Medical University Of Gdansk |
| 20624682 |
24 |
Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors. |
Balikesir University |
| 20590092 |
273 |
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. |
Universita Degli Studi Di Firenze |
| 19330012 |
3 |
Ligand-directed tosyl chemistry for protein labeling in vivo. |
Kyoto University |
| 20554206 |
10 |
A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potencies. |
Atat£Rk University |
| 20202722 |
138 |
Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides. |
Medical University Of Gdansk |
| 20430631 |
24 |
NO-releasing esters show carbonic anhydrase inhibitory action against human isoforms I and II. |
Atat£Rk University |
| 20211561 |
20 |
Inhibition studies of a beta-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides. |
Universit£ |
| 19751975 |
6 |
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors. |
Universita Degli Studi Di Firenze |
| 19527930 |
53 |
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms. |
University Of Tampere And Tampere University Hospital |
| 19375309 |
51 |
Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids. |
Universit£ |
| 19580287 |
27 |
Carbonic anhydrase-encoded dynamic constitutional libraries: toward the discovery of isozyme-specific inhibitors. |
Enscm/Umii/Umr-Cnrs 5635 |
| 19438226 |
80 |
Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial beta-carbonic anhydrases Rv1284 and Rv3273. |
Istanbul University |
| 19362844 |
107 |
Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes. |
Dumlupinar University |
| 19231207 |
22 |
Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. |
Ataturk University |
| 19121582 |
15 |
Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions. |
Centre Scientifique De Monaco |
| 19097911 |
41 |
Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors. |
University Of Namur |
| 19053764 |
101 |
Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates. |
Instituto Superior TéCnico |
| 18993072 |
18 |
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions. |
Balikesir University |
| 18819808 |
40 |
In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II. |
Ataturk University |
| 18348513 |
19 |
Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs. |
University Of Namur |
| 18353640 |
6 |
Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates. |
Universita Degli Studi Di Firenze |
| 17822907 |
90 |
Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity. |
Assiut University |
| 17442568 |
14 |
Benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulfonamides as inhibitors of carbonic anhydrase. |
Institute Of Biotechnology |
| 17257840 |
20 |
Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions. |
Università |
| 16809036 |
100 |
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors. |
Medical University Of Gdansk |
| 16168653 |
100 |
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides. |
Università |
| 16165351 |
45 |
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides. |
Università |
| 16033263 |
51 |
Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors. |
Università |
| 15908204 |
116 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes. |
Ospedale San Lazzaro |
| 15908201 |
51 |
Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxic tumors. |
Università |
| 15837325 |
69 |
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds. |
Ospedale San Lazzaro |
| 15837323 |
66 |
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols. |
University Of Bucharest |
| 15780637 |
3 |
Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II. |
University Of Naples 'Federico Ii |
| 15780631 |
55 |
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with complex fluorides, chlorides and cyanides. |
Università |
| 15664815 |
45 |
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. |
Università |
| 15501037 |
27 |
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet. |
Università |
| 15081040 |
4 |
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide. |
Bruker-Axs |
| 14640555 |
96 |
Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates. |
University Of Montpellier |
| 10649985 |
390 |
Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. |
Università |
| 8340917 |
19 |
Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase. |
Merck Research Laboratories |
| 28389112 |
72 |
Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII. |
Universit£ |
| 28416101 |
60 |
N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII. |
Latvian Institute Of Organic Synthesis |
| 28347633 |
92 |
Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs. |
Universit£ |
| 28343756 |
8 |
Inhibition of Malassezia globosa carbonic anhydrase with phenols. |
University Of Tehran |
| 28453941 |
114 |
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. |
Universit£ |
| 21679053 |
22 |
Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases. |
University Of Tampere And Tampere University Hospital |
| 27570878 |
7 |
A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase. |
Utrecht University |
| 26773755 |
20 |
Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives. |
Indian Institute Of Integrative Medicine |
| 12065583 |
3 |
Identification of a novel human eicosanoid receptor coupled to G(i/o). |
Tanabe Seiyaku |
| 10945872 |
14 |
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A. |
Smithkline Beecham Pharmaceuticals |
| 10900230 |
11 |
Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s). |
University Of Michigan |
| 7830490 |
21 |
SR 142801, the first potent non-peptide antagonist of the tachykinin NK3 receptor. |
Sanofi Recherche |
| 7815325 |
65 |
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. |
Duke University |
| 7796807 |
51 |
The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants. |
Synaptic Pharmaceutical |
| 3130534 |
3 |
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. |
Tokushima Research Institute |
| 2664084 |
17 |
Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein. |
Albany Medical College |
| 2547939 |
11 |
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor. |
Abbott Laboratories |
| 2537406 |
2 |
Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells. |
University Of Arizona |
| 19884015 |
17 |
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties. |
Daiichi Sankyo |
| 19900813 |
12 |
Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes. |
Astellas Pharma |
| 19764794 |
60 |
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline. |
Amgen |
| 19682971 |
48 |
A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease. |
Novartis Institute For Tropical Diseases |
| 19394217 |
14 |
2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists. |
Banyu Pharmaceutical |
| 19267461 |
53 |
Novel tricyclic inhibitors of IkappaB kinase. |
Bristol-Myers Squibb |
| 19007201 |
20 |
Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase. |
Roche Palo Alto |
| 19175319 |
19 |
Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays (dagger). |
Pfizer |
| 17459705 |
26 |
Novel inhibitors of fatty acid amide hydrolase. |
Bristol-Myers Squibb |
| 18678489 |
39 |
Discovery of a potent and selective aurora kinase inhibitor. |
Sunesis Pharmaceuticals |
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