The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26358162 |
27 |
Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases: Into clinical testing with pre-adaptive pharmacophores. |
Bayer Healthcare |
25782055 |
9 |
Discovery of a Cyclic Boronic Acidß-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases. |
Rempex Pharmaceuticals |
25650311 |
76 |
Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3. |
Chang Gung University |
25408826 |
8 |
Neutrophil elastase inhibitors as potential anti-inflammatory therapies. |
Therachem Research Medilab (India) |
915907 |
6 |
Proteinase inhibitors. I. Inhibitors of elastase. |
TBA |
24556381 |
4 |
Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esterase. |
Universidad De Buenos Aires |
24224573 |
31 |
Optimization of O3-acyl kojic acid derivatives as potent and selective human neutrophil elastase inhibitors. |
Universidade De Lisboa |
24135727 |
7 |
Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors. |
Emory University |
24102612 |
105 |
Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity. |
University Of Bari &Quot;Aldo Moro&Quot |
23844670 |
52 |
Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase. |
Universit£ |
23719288 |
41 |
Discovery of novel series of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as human chymase inhibitors using structure-based drug design. |
Asubio Pharma |
23350733 |
10 |
Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. |
University Of Florida |
2299617 |
173 |
Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase. |
Syntex Research |
4068006 |
46 |
Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones. |
TBA |
21413808 |
170 |
Synopsis of some recent tactical application of bioisosteres in drug design. |
Bristol-Myers Squibb Pharmaceutical Research And Development |
22882079 |
26 |
Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase. |
Aarhus University |
22595175 |
18 |
N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases. |
University Of Lisbon |
17535802 |
91 |
Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. |
Merck Research Laboratories |
18318470 |
1 |
X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives. |
Wichita State University |
18078761 |
2 |
Bornyl (3,4,5-trihydroxy)-cinnamate--an optimized human neutrophil elastase inhibitor designed by free energy calculations. |
Albert-Ludwigs-University Of Freiburg |
18053726 |
364 |
Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality. |
Johnson & Johnson Pharmaceutical Research & Development |
18290604 |
1 |
Azetidine-2,4-diones (4-oxo-beta-lactams) as scaffolds for designing elastase inhibitors. |
Universidade De Lisboa |
18247547 |
6 |
Discovery of a potent, selective, and orally active proteasome inhibitor for the treatment of cancer. |
Cephalon |
17470393 |
6 |
Resisting degradation by human elastase: commonality of design features shared by 'canonical' plant and bacterial macrocyclic protease inhibitor scaffolds. |
Imperial College |
16078825 |
8 |
Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design. |
Schering-Plough Research Institute |
12190311 |
37 |
Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151). |
Gsk |
11312926 |
39 |
Development of orally active nonpeptidic inhibitors of human neutrophil elastase. |
Cortech |
10669559 |
180 |
Protease inhibitors: current status and future prospects. |
University Of Queensland |
9191965 |
58 |
Discovery and biological activity of orally active peptidyl trifluoromethyl ketone inhibitors of human neutrophil elastase. |
Zeneca Pharmaceuticals |
7799404 |
22 |
Inhibition of human neutrophil elastase with peptidyl electrophilic ketones. 2. Orally active PG-Val-Pro-Val pentafluoroethyl ketones. |
Marion Merrell Dow Research Institute |
8064791 |
18 |
2,6-Disubstituted aryl carboxylic acids, leaving groups"par excellence" for benzisothiazolone inhibitors of human leukocyte elastase. |
Sterling Winthrop Pharmaceutical Research Division |
1578486 |
53 |
Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G. |
Georgia Institute Of Technology |
1542092 |
38 |
Inhibition of human leukocyte elastase (HLE) by N-substituted peptidyl trifluoromethyl ketones. |
Boehringer Ingelheim Pharmaceuticals |
1433188 |
7 |
Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol. |
Merck Research Laboratories |
11294386 |
5 |
The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate. |
Glaxowellcome Medicines Research Centre |
11206469 |
14 |
Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams. |
Glaxowellcome Medicines Research Centre |
11055335 |
27 |
Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors. |
Boehringer Ingelheim Pharmaceuticals |
10360758 |
10 |
Metallopeptide approach to the design of biologically active ligands: design of specific human neutrophil elastase inhibitors. |
Palatin Technologies |
21923104 |
12 |
HLE-inhibitory alkaloids with a polyketide skeleton from the marine-derived fungus Coniothyrium cereale. |
University Of Bonn |
21741848 |
66 |
Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase. |
Universit£ |
20823284 |
9 |
Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease. |
Boehringer Ingelheim (Canada) |
20970895 |
4 |
2-Azetidinone--a new profile of various pharmacological activities. |
Barkatullah University |
20638756 |
1 |
Inhibitors of human neutrophil elastase based on a highly functionalized N-amino-4-imidazolidinone scaffold. |
Wichita State University |
19841155 |
29 |
MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease. |
Merck Research Laboratories |
20417587 |
14 |
Synthesis and evaluation of benzoxazinone derivatives on activity of human neutrophil elastase and on hemorrhagic shock-induced lung injury in rats. |
Chang Gung University |
20102150 |
35 |
Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif. |
Johnson & Johnson Pharmaceutical Research And Development |
19772295 |
5 |
Potent inhibitors of beta-tryptase and human leukocyte elastase based on the MCoTI-II scaffold. |
Imperial College |
19665376 |
48 |
Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C. |
Merck Frosst Canada |
20004577 |
6 |
Evaluation of human neutrophil elastase inhibitory effect of iridoid glycosides from Hedyotis diffusa. |
Korea Research Institute Of Bioscience And Biotechnology |
19908842 |
84 |
Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB. |
National Human Genome Research Institute |
19904934 |
31 |
4-Oxo-beta-lactams (azetidine-2,4-diones) are potent and selective inhibitors of human leukocyte elastase. |
University Of Lisbon |
19577470 |
49 |
Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase. |
Activx Biosciences |
3550086 |
31 |
Design of alternate substrate inhibitors of serine proteases. Synergistic use of alkyl substitution to impede enzyme-catalyzed deacylation. |
TBA |
| 24 |
Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture |
TBA |
| 5 |
Synthesis of 7α-methoxy-2-(1,3-dithiolan-2-ylidene)cephem sulphones. A new series of human leukocyte elastase inhibitors |
TBA |
| 45 |
A comparative SAR and computer modeling study of benzisothiazolone, mechanism-based inhibitors with porcine pancreatic and human leukocyte elastase |
TBA |
| 8 |
Tricyclic cephems as inhibitors of human leukocyte elastase. thieno[3,4-c]cepham sulfones and pyrrolo[3,4-c]cepham sulfones |
TBA |
| 7 |
Tricyclic cephems as inhibitors of human leukocyte elastase. Furo[3,4-c]cepham sulfones |
TBA |
| 55 |
The design of potent and stable benzisothiazolone inhibitors of human leukocyte elastase |
TBA |
| 18 |
Inhibitors of human leukocyte elastase. 3.1 inhibition by tetrahydrobenzisothiazolinylmethyl aryl carboxylates |
TBA |
| 14 |
Inhibitors of human leukocyte elastase. 2.1 synthesis and sar of benzisothiazolinylmethyl aryl ethers |
TBA |
| 1 |
Phosphorous acid analogs of L-680,833, a potent monocyclic β-lactam inhibitor of human leukocyte elastase |
TBA |
| 12 |
Alkoxy substituted benzisothiazolone (BIT) derivatives: potent inhibitors of human leukocyte elastase |
TBA |
| 27 |
Synthesis and porcine pancreatic elastase inhibitory evaluation of 6α-(sulfonyl)oxy-and 6α-chloropenicillanate sulfone esters and 3α-(acyloxy)methyl-6α-chloropenam sulfones |
TBA |
| 46 |
1,3-Oxazino[4,5-b]indole-2,4-(1H,9H)-diones and 5,6-dimethylpyrrolo-[2,3-d]-1,3-oxazin-2,4-(1H,7H)-diones as serine protease inhi... |
TBA |
| 2 |
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases |
TBA |
| 18 |
Examination of peptidic α′,β-diamino-α,α-difluoroketones as inhibitors of human leukocyte elastase |
TBA |
| 19 |
A benzisothiazolone class of potent, selective mechanism-based inhibitors of human leukocyte elastase |
TBA |
| 4 |
elastase inhibitors containing conformationally restricted lactams as P3-P2 dipeptide replacements |
TBA |
| 7 |
Janus compounds: dual inhibitors of proteinases |
TBA |
| 30 |
Enantioselective synthesis and antielastase activity of 1,3,4-trisubstituted and 3,4-disubstituted β-lactam antibiotics |
TBA |
| 6 |
Inhibition of human leukocyte elastase. 7. Inhibition by 6-substituted penicillin amides. |
TBA |
| 32 |
Inhibition of human leukocyte elastase. 6. Inhibition by 6-substituted penicillin esters. |
TBA |
| 18 |
Inhibition of human leukocyte elastase. 5. Inhibition by 6-alkyl substituted penem benzyl esters. |
TBA |
| 17 |
Inhibition of human leukocyte elastase (HLE) by novel bicyclic β-lactams |
TBA |
| 13 |
Cephem sulfones as inactivators of human leukocyte elastase. II. Keto-enol tautomerish in cephem-4-ketones. |
TBA |
| 2 |
The effect of N-acyl substituents on the stability of monocyclic β-lactam inhibitors of human leukocyte elastase |
TBA |
| 1 |
Potential mechanism-based inhibitors of proteolytic enzymes |
TBA |
| 6 |
Synthesis of a peptidyl 2,2-difluoro-3-aminopropionate |
TBA |
| 1 |
A general synthesis of 4-alkyl/aryl substituted saccharins |
TBA |
18701300 |
55 |
Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides. |
University Of Leipzig |
17419055 |
30 |
Identification of 6-substituted 4-arylsulfonyl-1,4-diazepane-2,5-diones as a novel scaffold for human chymase inhibitors. |
Daiichi Asubio Pharma |
17145787 |
8 |
Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131. |
Gilead Sciences |
15588093 |
3 |
A systematic approach to the optimization of substrate-based inhibitors of the hepatitis C virus NS3 protease: discovery of potent and specific tripeptide inhibitors. |
Boehringer Ingelheim (Canada) |
12668020 |
29 |
Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitors. |
3-Dimensional Pharmaceuticals |
12565935 |
5 |
Synthesis and evaluation of delta-lactams (piperazones) as elastase inhibitors. |
The Oxford Centre For Molecular Sciences And The Dyson Perrins Laboratory |
12540231 |
39 |
Phenethyl amides as novel noncovalent inhibitors of hepatitis C virus NS3/4A protease: discovery, initial SAR, and molecular modeling. |
Mrl Rome |
12467634 |
67 |
3-Acylamino-azetidin-2-one as a novel class of cysteine proteases inhibitors. |
Currently Naeja Pharmaceutical |
12372533 |
69 |
P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
12161131 |
1 |
Clarification of mechanism of human sputum elastase inhibition by a new inhibitor, ONO-5046, using electrospray ionization mass spectrometry. |
Minase Research Institute |
11844670 |
27 |
Design and synthesis of peptide-based carboxylic acid-containing transition-state inhibitors of human neutrophil elastase. |
Dainippon Pharmaceutical |
11425539 |
23 |
Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones. |
Shionogi |
11327591 |
1 |
Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors. |
Ineti |
11212109 |
14 |
The identification of alpha-ketoamides as potent inhibitors of hepatitis C virus NS3-4A proteinase. |
Roche Discover Welwyn |
11150162 |
15 |
Design and synthesis of new orally active nonpeptidic inhibitors of human neutrophil elastase. |
Colorado State University |
11078188 |
20 |
1-Oxacephem-based human chymase inhibitors: discovery of stable inhibitors in human plasma. |
Shionogi |
11078187 |
36 |
Synthesis and structure-activity relationships of a new class of 1-oxacephem-based human chymase inhibitors. |
Shionogi |
10866385 |
13 |
Mass spectrometry reveals elastase inhibitors from the reactive centre loop of alpha1-antitrypsin. |
The Oxford Centre For Molecular Sciences |
10639285 |
13 |
2-(diethylamino)thieno1,3??xazin-4-ones as stable inhibitors of human leukocyte elastase. |
University Of Leipzig |
10522707 |
16 |
2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease. |
Glaxowellcome Medicines Research Centre |
10476876 |
1 |
Molecular structure of FR901277, a novel inhibitor of human leukocyte elastase, and its binding mode simulation. |
Fujisawa Pharmaceutical |
10340616 |
6 |
Synthesis and in vitro and in vivo evaluation of the 2-(6'methoxy-3',4'-dihydro-1'-naphtyl)-4H-3,1-benzoxazin-4- one as a new potent substrate inhibitor of human leukocyte elastase. |
Università |
9873654 |
37 |
5,5-trans lactone-containing inhibitors of serine proteases: identification of a novel, acylating thrombin inhibitor. |
Glaxo Wellcome Research And Development |
9873610 |
48 |
Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease. |
Boehringer Ingelheim (Canada) |
9871780 |
85 |
Inhibition of human cytomegalovirus protease N(o) with monocyclic beta-lactams. |
Boehringer Ingelheim (Canada) |
9871680 |
5 |
Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids. |
Proscript |
9871629 |
6 |
Preparation of alpha-keto ester enol acetates as potential prodrugs of human neutrophil elastase inhibitors. |
Cinc |
9822554 |
14 |
1,2-Benzisothiazol-3-one 1,1-dioxide inhibitors of human mast cell tryptase. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
9822552 |
2 |
Design and synthesis of hydrazinopeptides and their evaluation as human leukocyte elastase inhibitors. |
Institut Jacques Monod (Umr Cnrs 7592/UniversitéS Paris Vi And Vii) |
9767628 |
31 |
Syntheses of trans-5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles and trans-5-oxo-hexahydro-furo[3,2-b]pyrroles (pyrrolidine trans-lactams and trans-lactones): new pharmacophores for elastase inhibition. |
Glaxowellcome Medicines Research Centre |
9667976 |
58 |
beta-Lactam derivatives as inhibitors of human cytomegalovirus protease. |
Boehringer Ingelheim (Canada) |
9651152 |
20 |
Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones. |
Hoechst Marion Roussel |
9572899 |
19 |
Novel thieno[2,3-d][1,3]oxazin-4-ones as inhibitors of human leukocyte elastase. |
University Of Leipzig |
9406601 |
109 |
Peptidomimetic inhibitors of the human cytomegalovirus protease. |
Boehringer Ingelheim |
9379436 |
46 |
Orally active trifluoromethyl ketone inhibitors of human leukocyte elastase. |
Zeneca Pharmaceuticals |
9341917 |
69 |
7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase. |
Southern Methodist University |
9341916 |
30 |
Anionic- and lipophilic-mediated surface binding inhibitors of human leukocyte elastase. |
RhôNe-Poulenc Rorer |
9191969 |
31 |
Dual inhibition of human leukocyte elastase and lipid peroxidation: in vitro and in vivo activities of azabicyclo[2.2.2]octane and perhydroindole derivatives. |
Institut De Recherche Servier |
8676347 |
39 |
Nonpeptidic inhibitors of human neutrophil elastase. 7. Design, synthesis, and in vitro activity of a series of pyridopyrimidine trifluoromethyl ketones. |
Zeneca Pharmaceuticals |
8176703 |
14 |
Design of orally active, non-peptidic inhibitors of human leukocyte elastase. |
Zeneca Pharmaceuticals Group |
7966161 |
45 |
Cephem sulfones as inactivators of human leukocyte elastase. 5. 7 alpha-Methoxy- and 7 alpha-chloro-1,1-dioxocephem 4-ketones. |
Pharmacia-Farmitalia Carlo Erba |
7932559 |
42 |
Nonpeptidic inhibitors of human leukocyte elastase. 3. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of orally active 3-amino-6-phenylpyridin-2-one trifluoromethyl ketones. |
Zeneca Pharmaceuticals Group |
7932558 |
30 |
Nonpeptidic inhibitors of human leukocyte elastase. 2. Design, synthesis, and in vitro activity of a series of 3-amino-6-arylopyridin-2-one trifluoromethyl ketones. |
Zeneca Pharmaceuticals Group |
7932532 |
23 |
Non-peptidic inhibitors of human leukocyte elastase. 1. The design and synthesis of pyridone-containing inhibitors. |
Zeneca |
7877139 |
8 |
Orally bioavailable benzisothiazolone inhibitors of human leukocyte elastase. |
Sterling Winthrop |
7837246 |
39 |
Nonpeptidic inhibitors of human leukocyte elastase. 5. Design, synthesis, and X-ray crystallography of a series of orally active 5-aminopyrimidin-6-one-containing trifluoromethyl ketones. |
Zeneca Pharmaceuticals |
7837244 |
33 |
Non-peptidic inhibitors of human leukocyte elastase. 4. Design, synthesis, and in vitro and in vivo activity of a series of beta-carbolinone-containing trifluoromethyl ketones. |
Zeneca Pharmaceuticals |
7837243 |
25 |
Peptidyl alpha-ketoheterocyclic inhibitors of human neutrophil elastase. 2. Effect of varying the heterocyclic ring on in vitro potency. |
Zeneca Pharmaceuticals |
7837235 |
9 |
Nonpeptidic inhibitors of human leukocyte elastase. 6. Design of a potent, intratracheally active, pyridone-based trifluoromethyl ketone. |
Zeneca Pharmaceuticals |
7830264 |
16 |
Inhibition of human neutrophil elastase. 3. An orally active enol acetate prodrug. |
Marion Merrell Dow Research Institute |
7739015 |
12 |
Phosphonates and phosphinates: novel leaving groups for benzisothiazolone inhibitors of human leukocyte elastase. |
Sterling Winthrop Pharmaceuticals Research Division |
7629790 |
32 |
New orally active serine protease inhibitors. |
Minase Research Institute |
7608910 |
1 |
Orally active beta-lactam inhibitors of human leukocyte elastase. 3. Stereospecific synthesis and structure-activity relationships for 3,3-dialkylazetidin-2-ones. |
Merck Research Laboratories |
7562931 |
41 |
Peptidyl alpha-ketoheterocyclic inhibitors of human neutrophil elastase. 3. In vitro and in vivo potency of a series of peptidyl alpha-ketobenzoxazoles. |
Zeneca Pharmaceuticals |
7473596 |
35 |
A novel class of cyclic beta-dicarbonyl leaving groups and their use in the design of benzisothiazolone human leukocyte elastase inhibitors. |
Sterling Winthrop Pharmaceuticals Research Division |
3848491 |
5 |
Substituted 2-pyrones, 2-pyridones, and other congeners of elasnin as potential agents for the treatment of chronic obstructive lung diseases. |
TBA |
3844034 |
13 |
Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase. |
TBA |
3647139 |
9 |
Inhibition of human sputum elastase by substituted 2-pyrones. |
TBA |
3361575 |
65 |
(Acyloxy)benzophenones and (acyloxy)-4-pyrones. A new class of inhibitors of human neutrophil elastase. |
Searle Research And Development |
2391693 |
17 |
Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins. |
Merck Sharp And Dohme Research Laboratories |
2391692 |
27 |
Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides. |
Merck Sharp And Dohme Research Laboratories |
2391691 |
55 |
Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters. |
Merck Sharp And Dohme Research Laboratories |
2296031 |
48 |
Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. |
Merrell Dow Research Institute |
1479581 |
11 |
Inhibition of human leukocyte elastase by N-substituted peptides containing alpha,alpha-difluorostatone residues at P1. |
Boehringer Ingelheim Pharmaceuticals |
27863021 |
30 |
Synthesis and anticholinesterase activity of new substituted benzo[d]oxazole-based derivatives. |
Shahid Bahonar University Of Kerman |
27543433 |
6 |
Design, synthesis, and anticonvulsant activity of some derivatives of xanthone with aminoalkanol moieties. |
Jagiellonian University Medical College |
11714872 |
14 |
The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. |
Astrazeneca R&D |
7683725 |
30 |
5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase. |
Merck Research Laboratories |