The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28658574 |
124 |
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold To Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII. |
Universit£ |
| 28272885 |
126 |
Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action. |
Universit£ |
| 28253618 |
104 |
Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. |
University Of Delhi |
| 25432060 |
92 |
Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties. |
Atat£Rk University |
| 28075587 |
102 |
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis. |
University Of Florence |
| 27823879 |
88 |
New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs. |
Maastricht University Medical Centre |
| 1635066 |
17 |
Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity. |
Istituto Chimico Internazionale Dr. G. Rende |
| 3735316 |
8 |
N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure. |
TBA |
| 28065499 |
84 |
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors. |
Kurukshetra University |
| 28024887 |
52 |
5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations. |
Riga Technical University |
| 27939347 |
52 |
Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity. |
Universit£ |
| 27933963 |
60 |
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. |
Universit£ |
| 27396930 |
48 |
Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties. |
Universit£ |
| 27144971 |
60 |
PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas. |
Temple University |
| 27172398 |
20 |
An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C. |
Griffith University |
| 27316543 |
24 |
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors. |
Universit£ |
| 27166574 |
52 |
Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII. |
Kurukshetra University |
| 27137360 |
100 |
Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII. |
Kurukshetra University |
| 26805033 |
426 |
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII. |
Uppsala University |
| 26875933 |
72 |
Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma. |
Dais |
| 26840366 |
72 |
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII. |
Egyptian Russian University |
| 26741028 |
100 |
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. |
Universit£ |
| 26810836 |
28 |
Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111. |
University Of Florida College Of Medicine |
| 26810710 |
116 |
A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms. |
University Of Chieti-Pescara |
| 26688270 |
104 |
Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins. |
Universit£ |
| 26803577 |
92 |
Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII. |
Harran University |
| 26497049 |
110 |
Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. |
Sapienza University Of Rome |
| 26498394 |
105 |
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters. |
Universit£ |
| 26408817 |
69 |
Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII. |
Egyptian Russian University |
| 26498393 |
116 |
New natural product carbonic anhydrase inhibitors incorporating phenol moieties. |
Aristotle University Of Thessaloniki |
| 26432607 |
60 |
Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII. |
Universit£ |
| 26422787 |
68 |
Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII. |
Dumlupinar University |
| 26347950 |
32 |
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases. |
Griffith University |
| 26319622 |
12 |
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents. |
Universit£ |
| 26233435 |
76 |
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity. |
University Of Cagliari |
| 26264840 |
104 |
Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies. |
University Of Chieti-Pescara |
| 26160114 |
101 |
Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms. |
Saint Petersburg State University |
| 26191373 |
52 |
Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series. |
Institute Of Biomolecules Max Mousseron (Ibmm) |
| 26233796 |
68 |
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties. |
University Of Cagliari |
| 26203869 |
18 |
Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates. |
University Of Florida |
| 26105196 |
52 |
Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. |
Kurukshetra University |
| 26073006 |
56 |
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII. |
University Of Cagliari |
| 26048024 |
84 |
Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. |
Jazan University |
| 26088336 |
96 |
5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII. |
University Of Belgrade |
| 25921266 |
48 |
New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors. |
Siedlce University Of Natural Sciences And Humanities |
| 26007302 |
56 |
New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies. |
University Of Chieti-Pescara |
| 25875209 |
60 |
6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells. |
Latvian Institute Of Organic Synthesis |
| 25913118 |
95 |
Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII. |
Harran University |
| 25912674 |
52 |
Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives. |
Cairo University |
| 25846066 |
88 |
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action. |
Universit£ |
| 25766630 |
100 |
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. |
Universit£ |
| 25757603 |
79 |
New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity. |
Siedlce University Of Natural Sciences And Humanities |
| 25753329 |
56 |
Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action. |
Latvian Institute Of Organic Synthesis |
| 25147616 |
92 |
Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry. |
Universit£ |
| 25050167 |
40 |
Carbonic anhydrase inhibitors: design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives. |
Bharati Vidyapeeth'S College Of Pharmacy |
| 25027802 |
56 |
Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies. |
Sapienza University Of Rome |
| 25022971 |
124 |
Furazan and furoxan sulfonamides are stronga-carbonic anhydrase inhibitors and potential antiglaucoma agents. |
Universit£ |
| 25019479 |
96 |
Cyclic tertiary sulfamates: selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives. |
Sapienza University Of Rome |
| 24948563 |
44 |
Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors. |
University Of Perugia |
| 25468040 |
77 |
Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV. |
TBA |
| 25456084 |
100 |
4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII. |
Kurukshetra University |
| 25442309 |
120 |
Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds. |
King Saud University |
| 25438758 |
44 |
Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: towards new carbonic anhydrase glycoinhibitors. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 25358084 |
143 |
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. |
Vilnius University |
| 25358036 |
64 |
A class of 4-sulfamoylphenyl-¿-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects. |
Universit£ |
| 25310626 |
80 |
Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups. |
Universit£ |
| 25267005 |
70 |
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones. |
Universit£ |
| 25255434 |
84 |
Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling. |
King Saud University |
| 25254302 |
44 |
Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates. |
Griffith University |
| 25245672 |
5 |
Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis,ß-glucuronidase inhibition activity, crystal structure, and POM analyses. |
King Saud University |
| 25156300 |
48 |
Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. |
Universidad Nacional De La Plata |
| 24878360 |
76 |
Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties. |
King Saud University |
| 24871996 |
124 |
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII. |
Medical University Of Gdansk |
| 24813742 |
98 |
Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors. |
Universit£ |
| 24713308 |
48 |
Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity. |
Siedlce University Of Natural Sciences And Humanities |
| 24589511 |
60 |
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties. |
University Of Cagliari |
| 24689792 |
54 |
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes. |
Griffith University |
| 24650641 |
110 |
Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII. |
Universit£ |
| 23647428 |
84 |
Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo. |
Universit£ |
| 23490152 |
15 |
Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition. |
University Of Florida |
| 23394791 |
177 |
4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. |
Vilnius University Institute Of Biotechnology |
| 23352754 |
28 |
o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII. |
Istanbul University |
| 23290254 |
92 |
Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII. |
Salman Bin Abdulaziz University |
| 23266178 |
115 |
Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV. |
National University Of La Plata |
| 23206986 |
259 |
QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII. |
Romanian Academy |
| 23159038 |
2 |
Characterization of human carbonic anhydrase XII stability and inhibitor binding. |
Vilnius University Institute Of Biotechnology |
| 23098607 |
2 |
Carbonic anhydrase IX as a target for metastatic disease. |
University Of Manchester |
| 23018095 |
36 |
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors. |
Universit£ |
| 23010455 |
108 |
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases. |
Universidad Nacional De La Plata |
| 22892213 |
168 |
Natural product coumarins that inhibit human carbonic anhydrases. |
Griffith University |
| 22705188 |
73 |
Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: new selective tumor-associated carbonic anhydrase inhibitors. |
Superacide Et Chimie Des Syst£Mes£ |
| 22668600 |
200 |
Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. |
Universit£ |
| 23265898 |
20 |
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors. |
Universit£ |
| 23241068 |
84 |
Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases. |
Latvian Association Of Human Genetics |
| 22910138 |
96 |
Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII. |
TBA |
| 23067387 |
105 |
Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms. |
Universit£ |
| 22894736 |
99 |
Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment. |
The Hebrew University Of Jerusalem |
| 22775345 |
74 |
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 22621623 |
44 |
Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts. |
University Of Manchester |
| 22901388 |
76 |
Inhibition ofa-class cytosolic human carbonic anhydrases I, II, IX and XII, andß-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors. |
Universit£ |
| 22721713 |
200 |
Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 22276570 |
112 |
Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo. |
Universit£ |
| 22487176 |
109 |
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins. |
Universit£ |
| 20674354 |
79 |
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV. |
Universit£ |
| 20605094 |
91 |
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
University Of Florida |
| 20598552 |
24 |
Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations. |
University Of Florida |
| 20472429 |
80 |
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 20201556 |
174 |
Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases. |
Griffith University |
| 20185318 |
132 |
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. |
Universit£ |
| 19911821 |
273 |
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. |
Universita Degli Studi Di Firenze |
| 20028100 |
78 |
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. |
Universit£ |
| 19827837 |
52 |
S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases. |
Griffith University |
| 18406497 |
66 |
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation. |
University Of Namur |
| 19286378 |
75 |
Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties. |
Griffith University |
| 19186056 |
60 |
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases. |
Universit£ |
| 18359629 |
84 |
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 18042384 |
60 |
Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 17475500 |
130 |
Carbonic anhydrases as targets for medicinal chemistry. |
Universit£ |
| 17314045 |
11 |
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I. |
Universit£ |
| 17157501 |
72 |
Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides. |
Griffith University |
| 17228881 |
141 |
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. |
Kochi Medical School |
| 16290146 |
30 |
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II"selective" inhibitor celecoxib. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 15686894 |
101 |
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? |
Universit£ |
| 16039848 |
93 |
Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. |
Kochi Medical School |
| 16039853 |
89 |
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma. |
Universita Degli Studi |
| 22377674 |
80 |
Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII. |
Universit£ |
| 22370338 |
183 |
Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases. |
Griffith University |
| 22365761 |
144 |
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. |
Universit£ |
| 22077347 |
44 |
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 21852133 |
68 |
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II. |
University Of Alberta |
| 21851094 |
92 |
Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors. |
Griffith University |
| 21821413 |
65 |
Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 21820216 |
75 |
Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives. |
Medical University Of Gdansk |
| 21515057 |
153 |
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies. |
Universit£ |
| 21723123 |
48 |
N-ß-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. |
Universidad Nacional De La Plata |
| 21470859 |
52 |
Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 21549597 |
71 |
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. |
U.O. Oculistica Az. Usl 3 |
| 21361354 |
112 |
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis. |
Universita` Degli Studi Di Firenze |
| 21314129 |
76 |
Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors. |
Griffith University |
| 21251841 |
90 |
A newß-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. |
University Of Montpellier |
| 21282059 |
48 |
Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. |
University Of Calgary |
| 20554082 |
76 |
Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII. |
Medical University Of Gdansk |
| 20590092 |
273 |
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. |
Universita Degli Studi Di Firenze |
| 20202722 |
138 |
Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides. |
Medical University Of Gdansk |
| 19751975 |
6 |
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors. |
Universita Degli Studi Di Firenze |
| 19527930 |
53 |
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms. |
University Of Tampere And Tampere University Hospital |
| 17257840 |
20 |
Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions. |
Università |
| 16809036 |
100 |
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors. |
Medical University Of Gdansk |
| 16168653 |
100 |
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides. |
Università |
| 15908204 |
116 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes. |
Ospedale San Lazzaro |
| 29048889 |
7 |
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX). |
University Of Florence |
| 28389112 |
72 |
Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII. |
Universit£ |
| 29466001 |
208 |
Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design. |
Vilnius University |
| 28416101 |
60 |
N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII. |
Latvian Institute Of Organic Synthesis |
| 28347633 |
92 |
Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs. |
Universit£ |
| 28453941 |
114 |
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. |
Universit£ |
| 27570878 |
7 |
A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase. |
Utrecht University |
| 10945872 |
14 |
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A. |
Smithkline Beecham Pharmaceuticals |
| 10900230 |
11 |
Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s). |
University Of Michigan |
| 7815325 |
65 |
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. |
Duke University |
| 3130534 |
3 |
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. |
Tokushima Research Institute |
| 2664084 |
17 |
Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein. |
Albany Medical College |
| 2547939 |
11 |
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor. |
Abbott Laboratories |
| 2537406 |
2 |
Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells. |
University Of Arizona |
| 19900813 |
12 |
Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes. |
Astellas Pharma |
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