33 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
23590342	105	ß-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.	F. Hoffmann-La Roche
10669559	180	Protease inhibitors: current status and future prospects.	University Of Queensland
8120867	70	Non-peptide renin inhibitors containing 2-(((3-phenylpropyl)phosphoryl)oxy)alkanoic acid moieties as P2-P3 replacements.	E. Merck Darmstadt
1635057	48	Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors.	Parke-Davis Pharmaceutical Research Division Of Warner-Lambert
2002469	80	Renin inhibitors containing conformationally restricted P1-P1' dipeptide mimetics.	Merck Sharp And Dohme Research Laboratories
1956045	88	Substrate analogue renin inhibitors containing replacements of histidine in P2 or isosteres of the amide bond between P3 and P2 sites.	E. Merck Darmstadt
2120440	23	Orally potent human renin inhibitors derived from angiotensinogen transition state: design, synthesis, and mode of interaction.	Kissei Pharmaceutical
3783611	55	Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin.	TBA
3531518	17	Design and synthesis of a potent and specific renin inhibitor with a prolonged duration of action in vivo.	TBA
3531517	17	Design and synthesis of potent and specific renin inhibitors containing difluorostatine, difluorostatone, and related analogues.	TBA
3906131	61	Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.	TBA
3906126	10	Difluorostatine- and difluorostatone-containing peptides as potent and specific renin inhibitors.	TBA
10386929	10	The sulfonimidamide as a novel transition state analog for aspartic acid and metallo proteases.	The University Of Kansas
	37	Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties	TBA
	23	Novel low molecular renin inhibitors which show good oral blood pressure lowering effects in marmosets	TBA
	22	Novel pseudosymmetric inhibitors of HIV-1 protease	TBA
	12	MDL 74147, a novel selective and soluble inhibitor of human renin. Synthesis, structure-activity relationship, species and protease selectivities.	TBA
15012981	3	Miraziridine A: natures blueprint towards protease class-spanning inhibitors.	Institut FüR Biochemie
11806706	7	Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles.	University Of Wisconsin-Madison
10354412	8	Simplified pepstatins: synthesis and evaluation of N-terminally modified analogues.	Institute Of Pharmaceutical Chemistry And Institute Of Pharmaceutical Technology
6809942	8	Synthesis of analogues of the carboxyl protease inhibitor pepstatin. Effect of structure in subsite P3 on inhibition of pepsin.	TBA
6767029	14	Synthesis of analogues of the carboxyl protease inhibitor pepstatin. Effects of structure on inhibition of pepsin and renin.	TBA
6406670	17	Synthesis of analogues of pepstatin. Effect of structure in subsites P1', P2', and P2 on inhibition of porcine pepsin.	TBA
3882966	28	Pepstatin-derived inhibitors of aspartic proteinases. A close look at an apparent transition-state analogue inhibitor.	TBA
3276890	28	Renin inhibitors. Design and synthesis of a new class of conformationally restricted analogues of angiotensinogen.	Abbott Laboratories
3126296	43	Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases.	University Of Wisconsin
3100803	16	Synthetic and enzyme inhibition studies of pepstatin analogues containing hydroxyethylene and ketomethylene dipeptide isosteres.	TBA
3100801	9	Inhibition of aspartic proteinases by peptides containing lysine and ornithine side-chain analogues of statine.	TBA
2067002	18	New pepstatin analogues: synthesis and pepsin inhibition.	University Of Arkansas
1404233	68	Renin inhibitors containing new P1-P1' dipeptide mimetics with heterocycles in P1'.	E. Merck Darmstadt
10580501	2	Kainate receptors are involved in synaptic plasticity.	University Of Bristol