46 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
25461326	20	Conformationally-locked N-glycosides: exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease.	Universitat Rovira I Virgili
25250725	295	Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors.	Leiden University
24803362	12	Concise synthesis of C-1-cyano-iminosugars via a new Staudinger/aza Wittig/Strecker multicomponent reaction strategy.	Technical University Graz
24657053	8	Docking and SAR studies of calystegines: binding orientation and influence on pharmacological chaperone effects for Gaucher's disease.	University Of Toyama
23880081	8	Rapid modifications of N-substitution in iminosugars: development of newß-glucocerebrosidase inhibitors and pharmacological chaperones for Gaucher disease.	Genomics Research Center
19397268	21	Rational design and synthesis of highly potent pharmacological chaperones for treatment of N370S mutant Gaucher disease.	Peking University
23106358	96	a-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based orala-glucosidase inhibitor for improving postprandial hyperglycemia.	University Of Toyama
22646221	11	Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase.	National Center For Advancing Translation Sciences
22762530	2	Conformationally-locked N-glycosides with selectiveß-glucosidase inhibitory activity: identification of a new non-iminosugar-type pharmacological chaperone for Gaucher disease.	Universitat Rovira I Virgili
22512696	61	Potent aminocyclitol glucocerebrosidase inhibitors are subnanomolar pharmacological chaperones for treating gaucher disease.	Institut De Qu£Mica Avan£Ada De Catalunya (Iqac-Csic)
22360565	20	Rapid assembly of a library of lipophilic iminosugars via the thiol-ene reaction yields promising pharmacological chaperones for the treatment of Gaucher disease.	University Of British Columbia
24900357	16	The myo-1,2-Diaminocyclitol Scaffold Defines Potent Glucocerebrosidase Activators and Promising Pharmacological Chaperones for Gaucher Disease.	TBA
20557054	56	Click chemistry approach to new N-substituted aminocyclitols as potential pharmacological chaperones for Gaucher disease.	Universitat De Barcelona
18595718	51	In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures.	Hokuriku University
10843222	17	Novel alpha-glucosidase inhibitors with a tetrachlorophthalimide skeleton.	University Of Tokyo
10098675	6	Homoisofagomines: chemical-enzymatic synthesis and evaluation as alpha- and beta-glucosidase inhibitors.	Technische Universit£T Berlin
9871687	6	A new strong inhibitor of beta-mannosidase.	S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�
	63	Potent glycosidase inhibitors, N-phenyl cyclic isourea derivatives of 5-amino- and 5-amino-1-C-(hydroxymethyl)-cyclopentane-1,2,3,4-tetraols	TBA
	15	The Interaction of Anhydroalditols with Sweet-Almond -glucosidase and Escherichia coli -galactosidase: implications for the design of potent glycosidase inhibitors	TBA
21862336	9	Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes.	University Of Reading
21546253	41	Docking and SAR studies of D- and L-isofagomine isomers as humanß-glucocerebrosidase inhibitors.	University Of Toyama
21370884	80	New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening.	Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)
21292481	4	Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease.	Aarhus University
24900289	155	Identification of Potent and Selective Glucosylceramide Synthase Inhibitors from a Library of N-Alkylated Iminosugars	TBA
17187079	1	Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.	Harvard Medical School
20231099	9	Synthesis of new beta-1-C-alkylated imino-L-iditols: A comparative study of their activity as beta-glucocerebrosidase inhibitors.	Universit£
19931460	6	Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase.	Utrecht University
	37	Synthesis of a new inhibitor of α-fucosidase	TBA
	5	Synthesis of C2-symmetrical polyhydroxyazepanes as inhibitors of glycosidases	TBA
	6	β-Glucosidase inhibitors incorporating pyridinium as a glucosyl mimic	TBA
	25	Synthesis and biological activity of C-6 modified derivatives of the glucosidase inhibitor 1-deoxynojirimycin.	TBA
15165148	13	Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana.	Hokuriku University
11392550	5	Powerful probes for glycosidases: novel, fluorescently tagged glycosidase inhibitors.	Institut FüR Biochemie Der Technischen UniversitäT Graz
11327590	7	Novel, lipophilic derivatives of 2,5-dideoxy-2,5-imino-D-mannitol (DMDP) are powerful beta-glucosidase inhibitors.	Technische UniversitäT Graz
25359714	55	Enzymatic Studies of Isoflavonoids as Selective and Potent Inhibitors of Human Leukocyte 5-Lipo-Oxygenase.	Universidad De Santiago
14534366	25	Comparison of [Dmt1]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors.	Cornell University