The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 27855359 |
15 |
Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease. |
Korea Institute Of Science And Technology |
| 27688189 |
15 |
Synthesis and in vitro characterization of novel fluorinated derivatives of the translocator protein 18 kDa ligand CfO-DPA-714. |
Institute Of Biomedical Imaging (I2Bm) |
| 27876250 |
60 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH |
Jagiellonian University Medical College |
| 27353534 |
32 |
New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO. |
Vanderbilt University |
| 27050782 |
16 |
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas. |
University Of Pisa |
| 26988801 |
55 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. |
Jagiellonian University Medical College |
| 26355532 |
18 |
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM). |
Korea University Of Science And Technology (Ust) |
| 26218651 |
16 |
Synthesis and in vitro characterization of novel fluorinated derivatives of the TSPO 18 kDa ligand SSR180575. |
Institute Of Biomedical Imaging (I2Bm) |
| 26177193 |
30 |
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides. |
Universit£ |
| 25725375 |
22 |
Ether analogues of DPA-714 with subnanomolar affinity for the translocator protein (TSPO). |
Stanford University School Of Medicine |
| 24944744 |
3 |
Synthesis, Characterization, and in Vitro Evaluation of a New TSPO-Selective Bifunctional Chelate Ligand. |
Universit£ |
| 24580635 |
21 |
Structure-activity relationship refinement and further assessment of 4-phenylquinazoline-2-carboxamide translocator protein ligands as antiproliferative agents in human glioblastoma tumors. |
Universit£ |
| 24560538 |
5 |
Preparation and evaluation of novel pyrazolo[1,5-a]pyrimidine acetamides, closely related to DPA-714, as potent ligands for imaging the TSPO 18kDa with PET. |
Cea |
| 23521048 |
14 |
Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging. |
Vanderbilt University Institute Of Imaging Science (Vuiis) |
| 23352481 |
16 |
Design, synthesis and structure-activity relationship of novel tricyclic benzimidazolone derivatives as potent 18 kDa translocator protein (TSPO) ligands. |
Dainippon Sumitomo Pharma |
| 22884355 |
31 |
Design, synthesis and structure-activity relationships of novel benzoxazolone derivatives as 18 kDa translocator protein (TSPO) ligands. |
Dainippon Sumitomo Pharma |
| 10508441 |
64 |
Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies. |
Universit£ |
| 21790126 |
5 |
Synthesis and evaluation of novel carbon-11 labeled oxopurine analogues for positron emission tomography imaging of translocator protein (18 kDa) in peripheral organs. |
National Institute Of Radiological Sciences |
| 22902658 |
31 |
Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents. |
Ge Healthcare |
| 22489952 |
38 |
Synthesis and biological evaluation of 4-phenylquinazoline-2-carboxamides designed as a novel class of potent ligands of the translocator protein. |
Universit£ |
| 21824692 |
53 |
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein. |
Universit£ |
| 21741237 |
6 |
Synthesis of 6-[¹8F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET. |
Cea |
| 21428406 |
70 |
N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors. |
National Institute Of Mental Health |
| 21133364 |
26 |
Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands. |
National Institute Of Mental Health |
| 20727749 |
17 |
Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO). |
University Of Sydney |
| 20045646 |
11 |
New iodinated quinoline-2-carboxamides for SPECT imaging of the translocator protein. |
University Of Glasgow |
| 19217778 |
6 |
[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain. |
National Institute Of Radiological Sciences |
| 19133775 |
7 |
The translocator protein (18 kDa): central nervous system disease and drug design. |
Brain And Mind Research Institute |
| 18729350 |
65 |
Anxiolytic-like effects of N,N-dialkyl-2-phenylindol-3-ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis. |
Universit£ |
| 18834105 |
27 |
2-Phenyl-imidazo[1,2-a]pyridine compounds containing hydrophilic groups as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity and electrophysiological studies. |
Universita Degli Studi Di Bari |
| 18472268 |
15 |
Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor. |
Emory University |
| 18294852 |
13 |
Synthesis and structure-activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem. |
Universit£ |
| 17300167 |
8 |
N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[(131)I]iodo-5-me thoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain. |
National Institute Of Radiological Sciences |
| 16640334 |
10 |
[2-11C]isopropyl-, [1-11C]ethyl-, and [11C]methyl-labeled phenoxyphenyl acetamide derivatives as positron emission tomography ligands for the peripheral benzodiazepine receptor: radiosynthesis, uptake, and in vivo binding in brain. |
National Institute Of Radiological Sciences |
| 15084121 |
6 |
Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain. |
National Institute Of Radiological Sciences |
| 15027878 |
30 |
N,N-dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of potent and selective ligands at the peripheral benzodiazepine receptor. |
Universit£ |
| 12904061 |
17 |
Structure-activity relationships in carboxamide derivatives based on the targeted delivery of radionuclides and boron atoms by means of peripheral benzodiazepine receptor ligands. |
Universit£ |
| 11312914 |
53 |
Mapping and fitting the peripheral benzodiazepine receptor binding site by carboxamide derivatives. Comparison of different approaches to quantitative ligand-receptor interaction modeling. |
Universit£ |
| 9301675 |
53 |
Synthesis and binding affinity of 2-phenylimidazo[1,2-alpha]pyridine derivatives for both central and peripheral benzodiazepine receptors. A new series of high-affinity and selective ligands for the peripheral type. |
Universit£ |
| 9288173 |
56 |
Mapping the peripheral benzodiazepine receptor binding site by conformationally restrained derivatives of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3- isoquinolinecarboxamide (PK11195). |
Universit£ |
| 8784441 |
66 |
Synthesis, biological activity, and SARs of pyrrolobenzoxazepine derivatives, a new class of specific"peripheral-type" benzodiazepine receptor ligands. |
Universit£ |
| 8709127 |
29 |
Cardiovascular characterization of pyrrolo[2,1-d][1,5]benzothiazepine derivatives binding selectively to the peripheral-type benzodiazepine receptor (PBR): from dual PBR affinity and calcium antagonist activity to novel and selective calcium entry blockers. |
Universit£ |
| 7473601 |
11 |
A concerted study using binding measurements, X-ray structural data, and molecular modeling on the stereochemical features responsible for the affinity of 6-arylpyrrolo[2,1-d][1,5]benzothiazepines toward mitochondrial benzodiazepine receptors. |
Universit£ |
| 7990110 |
57 |
A comparative molecular field analysis model for 6-arylpyrrolo[2,1-d] [1,5]benzothiazepines binding selectively to the mitochondrial benzodiazepine receptor. |
Universit£ |
| 8182701 |
39 |
Novel ligands specific for mitochondrial benzodiazepine receptors: 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives. Synthesis, structure-activity relationships, and molecular modeling studies. |
Universit£ |
| 22244939 |
31 |
[¹¿?¿F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO). |
Ge Healthcare |
| 21916402 |
27 |
Synthesis and structure-activity relationship studies in translocator protein ligands based on a pyrazolo[3,4-b]quinoline scaffold. |
Universit£ |
| 20438080 |
10 |
Novel irreversible fluorescent probes targeting the 18 kDa translocator protein: synthesis and biological characterization. |
Universit£ |
| 20061068 |
9 |
Synthesis, structure and affinity of novel 3-alkoxy-1,2-dihydro-3H-1,4-benzodiazepin-2-ones for CNS central and peripheral benzodiazepine receptors. |
Institute Of The National Academy Of Sciences Of Ukraine |
| 19119848 |
4 |
Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET. |
National Institute Of Mental Health |
| 18557607 |
8 |
Synthesis and biological evaluation of substituted [18F]imidazo[1,2-a]pyridines and [18F]pyrazolo[1,5-a]pyrimidines for the study of the peripheral benzodiazepine receptor using positron emission tomography. |
Radiopharmaceuticals Research Institute |
| 18067245 |
11 |
Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo. |
National Institute Of Mental Health |
| 17286392 |
1 |
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor. |
Università |
| 15634024 |
70 |
Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands. |
Università |
| 12482423 |
6 |
[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR). |
National Institute Of Radiological Sciences |
| 12372538 |
22 |
Relating the structure, activity, and physical properties of ultrashort-acting benzodiazepine receptor agonists. |
Glaxosmithkline |
| 12213069 |
33 |
Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR). |
Universita' Degli Studi Di Siena |
| 9171882 |
7 |
Modulation of melphalan resistance in glioma cells with a peripheral benzodiazepine receptor ligand-melphalan conjugate. |
University Of Kansas |
| 8863805 |
35 |
Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem. |
Università |
| 8691438 |
48 |
(S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist. |
Pharmacia & Upjohn |
| 8411007 |
392 |
Chemistry, binding affinities, and behavioral properties of a new class of"antineophobic" mitochondrial DBI receptor complex (mDRC) ligands. |
Mayo Foundation |
| 2846836 |
3 |
Radioiodinated benzodiazepines: agents for mapping glial tumors. |
University Of Michigan Medical Center |
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