The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26260335 |
14 |
Tight binding enantiomers of pre-clinical drug candidates. |
Victoria University Of Wellington |
31484 |
4 |
Stereoelectronic factors in the binding of substrate analogues and inhibitors to purine nucleoside phosphorylase isolated from human erythrocytes. |
TBA |
22264015 |
29 |
N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase. |
Academy Of Sciences Of The Czech Republic |
19386496 |
3 |
Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II. |
Biocryst Pharmaceuticals |
19170524 |
38 |
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase. |
Industrial Research |
18778937 |
15 |
Immucillins in custom catalytic-site cavities. |
Albert Einstein College Of Medicine Of Yeshiva University |
17004717 |
22 |
Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activity. |
Universit£ |
15163207 |
27 |
Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase. |
Industrial Research |
14613329 |
11 |
Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase. |
Industrial Research |
12852771 |
26 |
Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase. |
Industrial Research |
8478902 |
18 |
Nucleosides. 5. Synthesis of guanine and formycin B derivatives as potential inhibitors of purine nucleoside phosphorylase. |
National Defense Medical Center |
8254607 |
36 |
Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group. |
Biocryst Pharmaceuticals |
1578487 |
12 |
Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-thienylmethyl)-4H-pyrrolo[3,2-d] pyrimidin-4-o |
Warner-Lambert |
1573639 |
17 |
Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues. |
Warner-Lambert |
3123692 |
6 |
Synthesis and evaluation of 5-amino-1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine and certain related nucleosides as inhibitors of purine nucleoside phosphorylase. |
Nucleic Acid Research Institute |
3091835 |
3 |
Inhibitors of human purine nucleoside phosphorylase. Synthesis, purine nucleoside phosphorylase inhibition, and T-cell cytotoxicity of 2,5-diaminothiazolo[5,4-d]pyrimidin-7(6H)-one and 2,5-diaminothiazolo[4,5-d]pyrimidin-7(6H)-one. Two thio isosteres of 8-aminoguanine. |
TBA |
3093681 |
7 |
Synthesis of 8-amino-3-deazaguanine via imidazole precursors. Antitumor activity and inhibition of purine nucleoside phosphorylase. |
TBA |
11959007 |
27 |
Benzimidazole-4,7-diones as inhibitors of protozoal (Toxoplasma gondii) purine nucleoside phosphorylase. |
Universit£ |
| 19 |
Phosphonate derivatives of N9-benzylguanine: a new class of potent purine nucleoside phosphorylase inhibitors |
TBA |
20817362 |
25 |
Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase. |
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra |
19620996 |
2 |
Enzymatic transition states and dynamic motion in barrier crossing. |
Albert Einstein College Of Medicine |
20189401 |
24 |
Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs. |
Tokyo University Of Pharmacy And Life Sciences |
20129792 |
10 |
Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies. |
Universidade Federal Da Bahia |
19386498 |
3 |
Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part I. |
Biocryst Pharmaceuticals |
18800772 |
18 |
A beta-fluoroamine inhibitor of purine nucleoside phosphorylase. |
Industrial Research |
17544667 |
10 |
Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP. |
Tokyo University Of Pharmacy And Life Sciences |
12502369 |
8 |
8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases. |
Industrial Research |
10522701 |
14 |
Synthesis and biological evaluation of 1,1-difluoro-2-(tetrahydro-3-furanyl)ethylphosphonic acids possessing a N9-purinylmethyl functional group at the ring. a new class of inhibitors for purine nucleoside phosphorylases. |
Tokyo University Of Pharmacy & Life Science |
8632418 |
21 |
Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase. |
Burroughs Wellcome |
8421291 |
73 |
Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine. |
Biocryst Pharmaceuticals |
8230137 |
14 |
9-[(Phosphonoalkyl)benzyl]guanines. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase. |
Burroughs Wellcome |
8164252 |
18 |
Structure-based design of inhibitors of purine nucleoside phosphorylase. 4. A study of phosphate mimics. |
Ciba-Geigy |
7699692 |
14 |
[[(Guaninylalkyl)phosphinico]methyl]phosphonic acids. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase. |
Burroughs Wellcome |