58 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27391135	28	3-Hydrazinoindolin-2-one derivatives: Chemical classification and investigation of their targets as anticancer agents.	Egyptian Russian University
27123900	17	Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.	Qilu University Of Technology
26774579	140	Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity.	Shanghai Institute Of Materia Medica
26481657	20	Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic.	Qilu University Of Technology
26191366	66	Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.	Indiana University School Of Medicine
26100442	17	Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design.	Qilu University Of Technology
25921264	21	Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.	Sanford-Burnham Medical Research Institute
25907364	29	A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.	Indiana University
25872983	57	Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors.	Chinese Academy Of Sciences
25865131	40	Synthesis and biological evaluation of open-chain analogs of cyclic peptides as inhibitors of cellular Shp2 activity.	Hebei University Of Science & Technology
25124112	54	Synthesis and biological evaluation of novel thiadiazole amides as potent Cdc25B and PTP1B inhibitors.	Liaoning Normal University
25003231	59	Therapeutic potential of targeting the oncogenic SHP2 phosphatase.	Indiana University School Of Medicine
25497963	19	Bioactive constituents from the green alga Caulerpa racemosa.	Nanchang University
24090912	54	Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy.	Chinese Academy Of Sciences
24012179	30	Calix[4]arene methylenebisphosphonic acids as inhibitors of protein tyrosine phosphatase 1B.	National Academy Of Sciences Of Ukraine
23957426	14	Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11).	Case Western Reserve University
23942421	43	The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors.	Chinese Academy Of Sciences
23713581	75	A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.	Indiana University School Of Medicine
23499238	15	Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors.	Chinese Academy Of Medical Sciences And Peking Union Medical College
23305444	171	Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.	Indiana University School Of Medicine
22444684	9	Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties.	Chinese Academy Of Sciences
22133902	9	Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors.	Indiana University
21116447	65	Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.	Indiana University School Of Medicine
18056643	8	Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.	Indiana University School Of Medicine
11741477	37	Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.	University Of Waterloo
22318165	85	Exploration ofa-aminophosphonate N-derivatives as novel, potent and selective inhibitors of protein tyrosine phosphatases.	Shanxi University
21745700	20	Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: novel construction of PTP1B inhibitors on a sugar scaffold.	East China University Of Science And Technology
21669525	18	Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.	Indiana University
21665482	62	Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.	East China University Of Science And Technology
21420867	68	Using small molecules to target protein phosphatases.	Max Planck Institute Of Molecular Physiology
21251827	60	A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides.	East China University Of Science And Technology
21193311	22	Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs.	H. Lee Moffitt Cancer Center And Research Institute
20363629	49	Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B.	Chinese Academy Of Sciences
19782562	10	Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp. SF-5060.	Silla University
20170098	21	Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).	Indiana University School Of Medicine
19846303	59	Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.	East China Normal University
	31	Novel phosphotyrosine mimetics in the design of peptide ligands for pp60src SH2 domain	TBA
17489579	4	An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity.	Burnham Institute For Medical Research
16884299	18	Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity.	University Of Bonn
14611852	34	Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity.	Roche Research Center
12951078	38	Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors.	Abbott Laboratories
9599224	10	Potent antagonists of the SH2 domain of Grb2: optimization of the X+1 position of 3-amino-Z-Tyr(PO3H2)-X+1-Asn-NH2.	Novartis Pharma
7473554	7	L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides.	National Cancer Institute-Bethesda
28395151	21	Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.	Chinese Academy Of Sciences
22380772	34	Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II.	Ataturk University
20797610	20	Functional studies of Plasmodium falciparum dipeptidyl aminopeptidase I using small molecule inhibitors and active site probes.	Stanford School Of Medicine
17337342	20	Affinity-based ranking of ligands for DPP-4 from mixtures.	Merck Research Laboratories