The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 27876250 |
60 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH |
Jagiellonian University Medical College |
| 24365162 |
126 |
Ligands of the neuropeptide Y Y2 receptor. |
The Scripps Research Institute |
| 24900634 |
36 |
Design and Synthesis of Peptide YY Analogues with C-terminal Backbone Amide-to-Ester Modifications. |
University Of Copenhagen |
| 24074877 |
135 |
Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. |
University Of Regensburg |
| 24090364 |
96 |
Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane and cis-cyclopentane β-amino acids shifts selectivity toward the Y(4) receptor. |
University Of Regensburg |
| 23726344 |
14 |
Heterocyclic modification of a novel bicyclo[3.1.0]hexane NPY1 receptor antagonist. |
Bristol-Myers Squibb Research And Development |
| 23582449 |
20 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor. |
Institute Of Organic Synthesis |
| 23466604 |
36 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds. |
Universit£ |
| 23403082 |
28 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. |
Broad Institute Of Mit And Harvard |
| 23265893 |
7 |
Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells. |
The Ohio State University |
| 16364642 |
21 |
Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists. |
Glaxosmithkline |
| 21074426 |
34 |
The identification of a series of novel, soluble non-peptidic neuropeptide Y Y2 receptor antagonists. |
Glaxosmithkline |
| 24900458 |
12 |
Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists. |
TBA |
| 22445286 |
19 |
Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. |
Pfizer |
| 20931963 |
112 |
Discovery of a novel 5-HT(3) antagonist/5-HT(1A) agonist 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878) as an orally bioavailable agent for irritable bowel syndrome. |
Aska Pharmaceutical |
| 20684563 |
176 |
Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential. |
H. Lundbeck |
| 19916528 |
3 |
5-OHKF and NorKA, depsipeptides from a Hawaiian collection of Bryopsis pennata: binding properties for NorKA to the human neuropeptide Y Y1 receptor. |
The University Of Mississippi |
| 18160282 |
40 |
Discovery of novel orally active ureido NPY Y5 receptor antagonists. |
Schering-Plough Research Institute |
| 1433176 |
26 |
Truncated, branched, and/or cyclic analogues of neuropeptide Y: importance of the pancreatic peptide fold in the design of specific Y2 receptor ligands. |
Salk Institute |
| 21782428 |
61 |
Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. |
Lundbeck Research Usa |
| 19616955 |
34 |
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor. |
Tsukuba Research Institute |
| 21493077 |
39 |
Red-fluorescent argininamide-type NPY Y1 receptor antagonists as pharmacological tools. |
Universit£T Regensburg |
| 21295475 |
21 |
Discovery and evaluation of pyrazolo[1,5-a]pyrimidines as neuropeptide Y1 receptor antagonists. |
Pfizer |
| 20813948 |
63 |
Spiroindolones, a potent compound class for the treatment of malaria. |
Swiss Tropical And Public Health Institute |
| 20688523 |
15 |
N(G)-Acyl-argininamides as NPY Y(1) receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. |
UniversitäT Regensburg |
| 20630754 |
33 |
Synthesis and structure-activity relationship of N-(3-azabicyclo[3.1.0]hex-6-ylmethyl)-5-(2-pyridinyl)-1,3-thiazol-2-amines derivatives as NPY Y5 antagonists. |
Glaxosmithkline |
| 20591666 |
66 |
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase. |
Università |
| 19864135 |
43 |
Discovery and SAR of cyclic isothioureas as novel NPY Y1 receptor antagonists. |
Schering-Plough Research Institute |
| 20042335 |
12 |
[Lys(DOTA)4]BVD15, a novel and potent neuropeptide Y analog designed for Y1 receptor-targeted breast tumor imaging. |
Universit£ |
| 19679469 |
26 |
Identification of positron emission tomography ligands for NPY Y5 receptors in the brain. |
Tsukuba Research Institute |
| 19640706 |
25 |
Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors. |
Tsukuba Research Institute |
| 19596193 |
72 |
Design, synthesis and evaluation of a novel cyclohexanamine class of neuropeptide Y Y1 receptor antagonists. |
Tsukuba Research Institute |
| 19487123 |
31 |
Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activity. |
Tsukuba Research Institute |
| 19581086 |
37 |
The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists. |
Glaxosmithkline |
| | 23 |
8-amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists |
TBA |
| | 13 |
Novel Y2-selective, reduced-size agonists of neuropeptide Y |
TBA |
| 19464889 |
43 |
Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists. |
Tsukuba Research Institute |
| 19459652 |
56 |
Discovery of tetrasubstituted imidazolines as potent and selective neuropeptide Y Y5 receptor antagonists: reduced human ether-a-go-go related gene potassium channel binding affinity and potent antiobesity effect. |
Tsukuba Research Institute |
| 19053784 |
19 |
Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. |
University Of Regensburg |
| 18851917 |
6 |
Modular synthesis of non-peptidic bivalent NPY Y1 receptor antagonists. |
UniversitäT Regensburg |
| 18752943 |
36 |
Syntheses and structure-activity relationships of novel, potent, and selective trans-2-[3-oxospiro[isobenzofuran-1(3H),1'-cyclohexan]-4'-yl]benzimidazole NPY Y5 receptor antagonists. |
Banyu Tsukuba Research Institute |
| 18723347 |
59 |
Design, syntheses, and structure-activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole derivatives. |
Banyu Tsukuba Research Institute |
| 18637668 |
38 |
(9S)-9-(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a selective and orally active neuropeptide Y Y5 receptor antagonist. |
Tsukuba Research Institute |
| 17425299 |
8 |
Novel selective neuropeptide Y2 receptor PEGylated peptide agonists reduce food intake and body weight in mice. |
Bayer Pharmaceuticals |
| 17292607 |
12 |
A long-acting selective neuropeptide Y2 receptor PEGylated peptide agonist reduces food intake in mice. |
Bayer Pharmaceuticals |
| 17127055 |
23 |
Novel carbazole derivatives as NPY Y1 antagonists. |
Glaxosmithkline |
| 17055726 |
68 |
Identification of selective neuropeptide Y2 peptide agonists. |
Bayer Pharmaceuticals |
| 16610810 |
39 |
Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32-36): development of an anorectic Y4 receptor selective agonist with picomolar affinity. |
University Of Cincinnati |
| 15546711 |
24 |
Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY1 receptor antagonists. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
| 15109631 |
86 |
Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists. |
Novartis Pharma |
| 15026066 |
22 |
Synthesis and evaluation of substituted 4-alkoxy-2-aminopyridines as novel neuropeptide Y1 receptor antagonists. |
Tsukuba Research Institute |
| 14741250 |
29 |
Synthesis of new thiophene and benzo[b]thiophene hydrazide derivatives as human NPY Y(5) antagonists. |
Universidad De Navarra |
| 12067557 |
24 |
Discovery of potent and selective small molecule NPY Y5 receptor antagonists. |
Lundbeck Research Usa |
| 11859006 |
15 |
Novel potent antagonists of human neuropeptide Y Y5 receptors. Part 3: 7-methoxy-1-hydroxy-1-substituted tetraline derivatives. |
Fujisawa Pharmaceutical |
| 11858996 |
32 |
Novel potent antagonists of human neuropeptide Y Y5 receptors. Part 2: substituted benzo[a]cycloheptene derivatives. |
Fujisawa Pharmaceutical |
| 11814801 |
24 |
Dihydropyridine neuropeptide Y Y(1) receptor antagonists. |
Pharmaceutical Research Institute |
| 11814791 |
13 |
Novel dihydropyrazine analogues as NPY antagonists. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
| 11428928 |
70 |
Synthesis and structure-activity relationships of trisubstituted phenyl urea derivatives as neuropeptide Y5 receptor antagonists. |
Amgen |
| 11334558 |
42 |
Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro(30), Tyr(32), Leu(34)]NPY(28-36)-NH2 (BW1911U90). |
University Of Cincinnati And Va Medical Centers |
| 10978189 |
115 |
Structure-activity studies including a Psi(CH(2)-NH) scan of peptide YY (PYY) active site, PYY(22-36), for interaction with rat intestinal PYY receptors: development of analogues with potent in vivo activity in the intestine. |
University Of Cincinnati Medical Center |
| 10915060 |
54 |
Structure-activity relationships of neuropeptide Y Y1 receptor antagonists related to BIBP 3226. |
University Of Regensburg |
| 10866375 |
50 |
Design, synthesis and SAR of a series of 2-substituted 4-amino-quinazoline neuropeptide Y Y5 receptor antagonists. |
Novartis Pharma |
| 10411482 |
63 |
1,3-Disubstituted benzazepines as novel, potent, selective neuropeptide Y Y1 receptor antagonists. |
Shionogi |
| 10201844 |
24 |
Synthesis and biological activity of oxo-7H-benzo[e]perimidine-4-carboxylic acid derivatives as potent, nonpeptide corticotropin releasing factor (CRF) receptor antagonists. |
Agouron Pharmaceuticals |
| 10201822 |
20 |
Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists. |
Eli Lilly |
| 10091705 |
51 |
Structure-activity relationships of a series of benzothiophene-derived NPY Y1 antagonists: optimization of the C-2 side chain. |
Eli Lilly |
| 9925722 |
18 |
Pharmacological treatment of obesity: therapeutic strategies. |
The R. W. Johnson Pharmaceutical Research Institute |
| 9871601 |
20 |
Structure-activity relationships of a series of 1-substituted-4-methylbenzimidazole neuropeptide Y-1 receptor antagonists. |
Eli Lilly |
| 9667962 |
28 |
Synthesis and evaluation of a series of novel 2-[(4-chlorophenoxy)methyl]benzimidazoles as selective neuropeptide Y Y1 receptor antagonists. |
Eli Lilly |
| 9371234 |
49 |
Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists. |
Eli Lilly |
| 8632403 |
14 |
Bis(31/31') ([CYS(31), Trp(32), Nva(34)] NPY-(31-36)): a specific NPY Y-1 receptor antagonist. |
University Of Cincinnati Medical Center |
| 8426366 |
44 |
Defining structural requirements for neuropeptide Y receptors using truncated and conformationally restricted analogues. |
Salk Institute |
| 8254609 |
61 |
Neuropeptide Y: Y1 and Y2 affinities of the complete series of analogues with single D-residue substitutions. |
Salk Institute |
| 28795803 |
20 |
Identification and Characterization of the First Selective Y |
Leipzig University |
| 27524297 |
212 |
A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance. |
Massachusetts Institute Of Technology |
| 26833890 |
18 |
Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease. |
Yogi Vemana University |
| 26469307 |
7 |
Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b. |
University Of Leipzig |
| 24406103 |
77 |
Effects of novel diarylpentanoid analogues of curcumin on secretory phospholipase A2 , cyclooxygenases, lipo-oxygenase, and microsomal prostaglandin E synthase-1. |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia |
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