The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26899595 |
32 |
A potent and selective inhibitor targeting human and murine 12/15-LOX. |
University Of California |
24924423 |
21 |
Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes. |
University Of California |
25462262 |
98 |
Development and evaluation of ST-1829 based on 5-benzylidene-2-phenylthiazolones as promising agent for anti-leukotriene therapy. |
Goethe-University Frankfurt |
24920381 |
77 |
SAR studies on curcumin's pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase. |
University Jena |
24393039 |
97 |
Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. |
National Institutes Of Health |
23871907 |
64 |
Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase. |
University Of Salerno |
19848434 |
27 |
Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes. |
University Of California Santa Cruz |
12608855 |
25 |
Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. |
University Of California Santa Cruz |
17826100 |
18 |
Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries. |
University Of California |
12036375 |
25 |
Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase. |
University Of California |
21868137 |
69 |
Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils. |
Gazi University |
21739938 |
72 |
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. |
National Human Genome Research Institute |
21319773 |
8 |
Natural compound cudraflavone B shows promising anti-inflammatory properties in vitro. |
University Of Veterinary And Pharmaceutical Sciences Brno |
21044840 |
47 |
Potent and selective 5-LO inhibitor bearing benzothiophene pharmacophore: discovery of MK-5286. |
Merck Frosst Centre For Therapeutic Research |
20866075 |
87 |
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1. |
National Human Genome Research Institute |
| 19 |
Catechol based inhibitors of 15-lipoxygenase |
TBA |
| 21 |
1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitor |
TBA |
15332838 |
2 |
An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge. |
University Of California |
17869117 |
153 |
Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2. |
Universidad De Santiago De Chile |
16480270 |
40 |
Novel human lipoxygenase inhibitors discovered using virtual screening with homology models. |
University Of California |
15267244 |
40 |
Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. |
University Of California |
8831760 |
108 |
5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones. |
Abbott Laboratories |
8246226 |
89 |
Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors. |
Ciba-Geigy |