The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28336141 |
53 |
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis. |
Glaxosmithkline |
| 22942319 |
16 |
Metabolism and pharmacokinetics of JM6 in mice: JM6 is not a prodrug for Ro-61-8048. |
Chdi Management/Chdi Foundation |
| 25590515 |
139 |
Development of a series of aryl pyrimidine kynurenine monooxygenase inhibitors as potential therapeutic agents for the treatment of Huntington's disease. |
Evotec (Uk) |
| 22525315 |
1 |
Ianthellamide A, a selective kynurenine-3-hydroxylase inhibitor from the Australian marine sponge Ianthella quadrangulata. |
Griffith University |
| 8126705 |
8 |
Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase. |
Universit£ |
| 9873646 |
41 |
4-Phenyl-4-oxo-butanoic acid derivatives inhibitors of kynurenine 3-hydroxylase. |
Pharmacia & Upjohn |
| | 4 |
Synthesis and activity of enantiopure (S) (m-nitrobenzoyl) alanine, potent kynurenine-3-hydroxylase inhibitor |
TBA |
| 10633043 |
27 |
Synthesis and SAR of 4-aryl-2-hydroxy-4-oxobut-2-enoic acids and esters and 2-amino-4-aryl-4-oxobut-2-enoic acids and esters: potent inhibitors of kynurenine-3-hydroxylase as potential neuroprotective agents. |
Glaxo Wellcome Research And Development |
| 9435907 |
23 |
Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase. |
F. Hoffmann-La Roche |
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