The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 18269227 |
14 |
Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. |
University Of Copenhagen |
| 17672447 |
25 |
Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA. |
University Of Copenhagen |
| 12238915 |
18 |
Ethyl (3S,4aR,6S,8aR)-6-(4-ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso-quinoline-3-carboxylic ester: a prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraine. |
Eli Lilly |
| 11087558 |
29 |
Biarylpropylsulfonamides as novel, potent potentiators of 2-amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic acid (AMPA) receptors. |
Nps Allelix |
| 9357531 |
58 |
Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes. |
University Of Bristol |
| 10969973 |
103 |
4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists. |
Eli Lilly |
| 20839777 |
25 |
Positive allosteric modulators of thea-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor. |
Merck Research Laboratories |
| 20356304 |
9 |
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonists: from bench to bedside. |
Novartis Pharma |
| 20096591 |
84 |
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
University Of California |
| 16879964 |
60 |
A novel class of AMPA receptor allosteric modulators. Part 1: design, synthesis, and SAR of 3-aryl-4-cyano-5-substituted-heteroaryl-2-carboxylic acid derivatives. |
Eli Lilly |
| 16872827 |
97 |
A novel class of positive allosteric modulators of AMPA receptors: design, synthesis, and structure-activity relationships of 3-biphenyl-4-yl-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid, LY2059346. |
Eli Lilly |
| 16610801 |
34 |
Structure-activity relationship studies on N3-substituted willardiine derivatives acting as AMPA or kainate receptor antagonists. |
University Walk |
| 15857151 |
37 |
Convergent synthesis and pharmacology of substituted tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid analogues. |
The Danish University Of Pharmaceutical Sciences |
| 14667236 |
61 |
2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5. |
The Danish University Of Pharmaceutical Sciences |
| 12747796 |
39 |
Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO). |
The Danish University Of Pharmaceutical Sciences |
| 12672235 |
15 |
(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology. |
The Danish University Of Pharmaceutical Sciences |
| 11985477 |
20 |
Design and synthesis of a novel series of 1,2-disubstituted cyclopentanes as small, potent potentiators of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid (AMPA) receptors. |
Nps Allelix |
| 10821708 |
138 |
4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists. |
Eli Lilly |
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