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11 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
25987375 20 Discovery of a novel Kv7 channel opener as a treatment for epilepsy.EBI Pfizer
25087753 240 Prediction of Thorough QT study results using action potential simulations based on ion channel screens.EBI University Of Oxford
25155913 32 Optimization of physicochemical properties and safety profile of novel bacterial topoisomerase type II inhibitors (NBTIs) with activity against Pseudomonas aeruginosa.EBI Astrazeneca
23121096 86 Ion channels as therapeutic targets: a drug discovery perspective.EBI Pfizer
22793372 66 Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor.EBI Vanderbilt University Medical Center
22910039 66 Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator.EBI Vanderbilt University Medical Center
24900334 89 N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy.EBI TBA
11170639 73 Current and novel approaches to the drug treatment of schizophrenia.EBI Merck Sharp And Dohme Research Laboratories
11356099 20 Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress.EBI Abbott Laboratories
21296466 20 Design, synthesis and biological activity of pyrazolo[1,5-a]pyrimidin-7(4H)-ones as novel Kv7/KCNQ potassium channel activators.EBI Hebei Medical University
11689069 18 Synthesis and activity of novel and selective I(Ks)-channel blockers.EBI Aventis Pharma Deutschland