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6 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28284804 56 Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.EBI Merck
24239482 9 Discovery of an intravenous hepatoselective glucokinase activator for the treatment of inpatient hyperglycemia.EBI Pfizer
23089526 21 The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus.EBI Pfizer
22196621 17 Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus.EBI Pfizer
20472448 25 Design, synthesis, and pharmacological evaluation of N-(4-mono and 4,5-disubstituted thiazol-2-yl)-2-aryl-3-(tetrahydro-2H-pyran-4-yl)propanamides as glucokinase activators.EBI Chinese Academy Of Sciences
15713416 30 Glucokinase-activating ureas.EBI Osi Pharmaceuticals