The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
25461330 |
28 |
Discovery of novel indole derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase. |
Chinese Academy Of Medical Sciences & Peking Union Medical College |
24530031 |
43 |
Design, synthesis and biological evaluation of 7-nitro-1H-indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase. |
Chinese Academy Of Medical Sciences & Peking Union Medical College |
21126019 |
73 |
Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase. |
Metabasis Therapeutics |
20542703 |
9 |
Discovery of potent and orally active tricyclic-based FBPase inhibitors. |
Daiichi Sankyo |
11140724 |
53 |
Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines. |
Pfizer |
21550236 |
44 |
Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase. |
F. Hoffmann-La Roche |
20116906 |
8 |
Designing inhibitors against fructose 1,6-bisphosphatase: exploring natural products for novel inhibitor scaffolds. |
Boston College |
20045638 |
19 |
Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors. |
Daiichi Sankyo |
19969452 |
112 |
Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of type-2 diabetes. |
F. Hoffmann-La Roche |
20055427 |
98 |
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics. |
Metabasis Therapeutics |
19762234 |
24 |
Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors. |
Daiichi Sankyo |
19419876 |
31 |
A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase. |
Boston College |
19348494 |
73 |
Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics. |
Metabasis Therapeutics |
18650089 |
65 |
Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites. |
F. Hoffmann-La Roche |
16446092 |
41 |
Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. |
Abbott Laboratories |