The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
23506825 |
71 |
Structure-based design, SAR analysis and antitumor activity of PI3K/mTOR dual inhibitors from 4-methylpyridopyrimidinone series. |
Pfizer |
24900568 |
27 |
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. |
Pfizer |
22749419 |
22 |
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Ka and mTOR. |
Pfizer |
22520630 |
21 |
Synthesis, biological evaluation and molecular docking studies of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents. |
Nanjing University |
22040023 |
63 |
Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1). |
Pfizer |
21882832 |
116 |
Synthesis and biological evaluation of novel analogues of the pan class I phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474). |
University Of Auckland |
19748269 |
21 |
Phosphoinositide-3-kinase (PI3K) inhibitors: identification of new scaffolds using virtual screening. |
University Of Auckland |