The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
23466229 |
18 |
PF-04859989 as a template for structure-based drug design: identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency. |
Pfizer |
24900560 |
16 |
Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. |
Pfizer |
24900455 |
45 |
Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia. |
TBA |
20684605 |
6 |
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement. |
University Of Piemonte Orientale Amedeo Avogadro |