The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
25987375 |
20 |
Discovery of a novel Kv7 channel opener as a treatment for epilepsy. |
Pfizer |
23121096 |
86 |
Ion channels as therapeutic targets: a drug discovery perspective. |
Pfizer |
22793372 |
66 |
Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor. |
Vanderbilt University Medical Center |
22910039 |
66 |
Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. |
Vanderbilt University Medical Center |