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58 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27750150 8 (5aR)-5a-C-Pentyl-4-epi-isofagomine: A powerful inhibitor of lysosomalß-galactosidase and a remarkable chaperone for mutations associated with GM1-gangliosidosis and Morquio disease type B.EBI Universit£
27789075 15 Strategy for designing selectivea-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas.EBI University Of Toyama
26361824 20 Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts.EBI University Of Seville
26838810 16 Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerfulß-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomalß-galactosidase.EBI Graz University Of Technology
26740154 4 Illuminating the binding interactions of galactonoamidines during the inhibition ofß-galactosidase (E. coli).EBI University Of Arkansas
26375725 20 Quaternary Indolizidine and Indolizidone Iminosugars as Potential Immunostimulating and Glycosidase Inhibitory Agents: Synthesis, Conformational Analysis, Biological Activity, and Molecular Docking Study.EBI Savitribai Phule Pune University (Formerly University Of Pune)
24026016 56 Synthesis and biological evaluation of N-(2-fluorophenyl)-2ß-deoxyfuconojirimycin acetamide as a potent inhibitor fora-l-fucosidases.EBI University Of Toyama
23611766 8 Skeletal rearrangement of seven-membered iminosugars: synthesis of (-)-adenophorine, (-)-1-epi-adenophorine and derivatives and evaluation as glycosidase inhibitors.EBI Universit£
23363020 3 Pharmacological chaperones as therapeutics for lysosomal storage diseases.EBI Amicus Therapeutics
20542427 1 Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles.EBI Academy Of Sciences Of The Czech Republic
23106358 96 a-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based orala-glucosidase inhibitor for improving postprandial hyperglycemia.EBI University Of Toyama
17536859 12 Isolation of glycosidase-inhibiting hyacinthacines and related alkaloids from Scilla socialis.EBI University Of Toyama
15771446 42 Biological properties of D- and L-1-deoxyazasugars.EBI Toyama Medical And Pharmaceutical University
15380224 12 Synthesis of 5a-carba-hexopyranoses and hexopyranosylamines, as well as 5a,5a'-dicarbadisaccharides, from 3,8-dioxatricyclo[4.2.1.0(2,4)]nonan-9-ol: glycosidase inhibitory activity of N-substituted 5a-carba-beta-gluco- and beta-galactopyranosylamines, and derivatives thereof.EBI Keio University
11931626 124 A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening.EBI Northwestern University
7966130 69 Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases.EBI Hokuriku University
12270152 24 Convenient synthesis and evaluation of enzyme inhibitory activity of several N-alkyl-, N-phenylalkyl, and cyclic isourea derivatives of 5a-carba-alpha-DL-fucopyranosylamine.EBI Keio University
11549468 54 New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives.EBI Universidad De Sevilla
11549453 77 Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors.EBI Section De Chimie De L'Universit£
 15 The Interaction of Anhydroalditols with Sweet-Almond -glucosidase and Escherichia coli -galactosidase: implications for the design of potent glycosidase inhibitorsEBI TBA
22290077 3 Concise synthesis of (+)-conduritol F and inositol analogues from naturally available (+)-proto-quercitol and their glucosidase inhibitory activity.EBI Chulalongkorn University
20971647 12 Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes.EBI Umr Cnrs 7201
22001090 4 Transformation of quercitols into 4-methylenecyclohex-5-ene-1,2,3-triol derivatives, precursors for the chemical chaperones N-octyl-4-epi-ß-valienamine (NOEV) and N-octyl-ß-valienamine (NOV).EBI Hokko Chemical Industry
21974950 8 A fluorescent probe for GM1 gangliosidosis relatedß-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol.EBI Industrial Research
21862336 9 Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes.EBI University Of Reading
21546253 41 Docking and SAR studies of D- and L-isofagomine isomers as humanß-glucocerebrosidase inhibitors.EBI University Of Toyama
21370884 80 New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening.EBI Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)
24900289 155 Identification of Potent and Selective Glucosylceramide Synthase Inhibitors from a Library of N-Alkylated IminosugarsEBI TBA
19515568 1 Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging.EBI Katholieke Universiteit Leuven
 37 Synthesis of a new inhibitor of α-fucosidaseEBI TBA
 5 Synthesis of C2-symmetrical polyhydroxyazepanes as inhibitors of glycosidasesEBI TBA
18996021 1 1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors.EBI Technische UniversitäT Graz
15165148 13 Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana.EBI Hokuriku University
12502331 28 New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica.EBI Hokuriku University
11858756 25 New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii.EBI Hokuriku University
16603357 6 Flexible synthesis and biological evaluation of novel 5-deoxyadenophorine analogues.EBI Université
16481162 17 Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols.EBI Technische UniversitäT Graz
14505649 21 Synthesis and glycosidase inhibitory activity of some N-substituted 6-deoxy-5a-carba-beta-DL- and L-galactopyranosylamines.EBI Keio University
12161128 35 Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: new leads as selective beta-galactosidase inhibitors.EBI Universidad De Sevilla
10560746 10 Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin.EBI Institut De Chimie Organique Et Analytique (I.C.O.A.)
10201849 3 Synthesis of alpha-C(1-->3)-mannopyranoside of N-acetylgalactosamine, a new beta-galactosidase inhibitor.EBI Institut De Chimie Organique De L'Université
30469042 9 Pharmaceutical significance of azepane based motifs for drug discovery: A critical review.EBI Wuhan Institute Of Technology
10021944 8 Specific, uncompetitive inhibition of beta-galactosidases by a 5,6-isopropylidenedioxyfuro[2,3-d]isoxazole-3-methanol derivative.EBI Institut De Chimie Organique De L'Université
26539626 5 Resveratrol-Related Polymethoxystilbene Glycosides: Synthesis, Antiproliferative Activity, and Glycosidase Inhibition.EBI Universit£
25295392 30 Structure-activity relationship of highly potent galactonoamidine inhibitors toward ?-galactosidase (Aspergillus oryzae).EBI University Of Arkansas
19674908 4 Synthesis of pentopyranosyl-containing thiodisaccharides. Inhibitory activity against beta-glycosidases.EBI Universidad De Buenos Aires
30270003 13 4-epi-Isofagomine derivatives as pharmacological chaperones for the treatment of lysosomal diseases linked to ?-galactosidase mutations: Improved synthesis and biological investigations.EBI Universit£
29674295 4 Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors.EBI University Of Seville
28692917 21 Tuning of ?-glucosidase and ?-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules.EBI University Of Seville
28844803 50 Picomolar inhibition of?-galactosidase (bovine liver) attributed to loop closure.EBI University Of Arkansas
28600215 15 A new type of pharmacological chaperone for GEBI Graz University Of Technology
29112434 7 N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer of?-Glucosidase Activity for the Treatment of Pompe Disease.EBI Universit£
27305312 4 Capture-Tag-Release: A Strategy for Small Molecule Labeling of Native Enzymes.BDB Fairfield University
26364932 22 Structure and Inhibition of Microbiome ß-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.BDB University Of North Carolina At Chapel Hill
23775891 83 New insights into the pharmacological chaperone activity of c2-substituted glucoimidazoles for the treatment of Gaucher disease.BDB Nankai University