The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27750150 |
8 |
(5aR)-5a-C-Pentyl-4-epi-isofagomine: A powerful inhibitor of lysosomalß-galactosidase and a remarkable chaperone for mutations associated with GM1-gangliosidosis and Morquio disease type B. |
Universit£ |
27789075 |
15 |
Strategy for designing selectivea-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas. |
University Of Toyama |
26361824 |
20 |
Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts. |
University Of Seville |
26838810 |
16 |
Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerfulß-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomalß-galactosidase. |
Graz University Of Technology |
26740154 |
4 |
Illuminating the binding interactions of galactonoamidines during the inhibition ofß-galactosidase (E. coli). |
University Of Arkansas |
26375725 |
20 |
Quaternary Indolizidine and Indolizidone Iminosugars as Potential Immunostimulating and Glycosidase Inhibitory Agents: Synthesis, Conformational Analysis, Biological Activity, and Molecular Docking Study. |
Savitribai Phule Pune University (Formerly University Of Pune) |
24026016 |
56 |
Synthesis and biological evaluation of N-(2-fluorophenyl)-2ß-deoxyfuconojirimycin acetamide as a potent inhibitor fora-l-fucosidases. |
University Of Toyama |
23611766 |
8 |
Skeletal rearrangement of seven-membered iminosugars: synthesis of (-)-adenophorine, (-)-1-epi-adenophorine and derivatives and evaluation as glycosidase inhibitors. |
Universit£ |
23363020 |
3 |
Pharmacological chaperones as therapeutics for lysosomal storage diseases. |
Amicus Therapeutics |
20542427 |
1 |
Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles. |
Academy Of Sciences Of The Czech Republic |
23106358 |
96 |
a-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based orala-glucosidase inhibitor for improving postprandial hyperglycemia. |
University Of Toyama |
17536859 |
12 |
Isolation of glycosidase-inhibiting hyacinthacines and related alkaloids from Scilla socialis. |
University Of Toyama |
15771446 |
42 |
Biological properties of D- and L-1-deoxyazasugars. |
Toyama Medical And Pharmaceutical University |
15380224 |
12 |
Synthesis of 5a-carba-hexopyranoses and hexopyranosylamines, as well as 5a,5a'-dicarbadisaccharides, from 3,8-dioxatricyclo[4.2.1.0(2,4)]nonan-9-ol: glycosidase inhibitory activity of N-substituted 5a-carba-beta-gluco- and beta-galactopyranosylamines, and derivatives thereof. |
Keio University |
11931626 |
124 |
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening. |
Northwestern University |
7966130 |
69 |
Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases. |
Hokuriku University |
12270152 |
24 |
Convenient synthesis and evaluation of enzyme inhibitory activity of several N-alkyl-, N-phenylalkyl, and cyclic isourea derivatives of 5a-carba-alpha-DL-fucopyranosylamine. |
Keio University |
11549468 |
54 |
New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives. |
Universidad De Sevilla |
11549453 |
77 |
Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. |
Section De Chimie De L'Universit£ |
| 15 |
The Interaction of Anhydroalditols with Sweet-Almond -glucosidase and Escherichia coli -galactosidase: implications for the design of potent glycosidase inhibitors |
TBA |
22290077 |
3 |
Concise synthesis of (+)-conduritol F and inositol analogues from naturally available (+)-proto-quercitol and their glucosidase inhibitory activity. |
Chulalongkorn University |
20971647 |
12 |
Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes. |
Umr Cnrs 7201 |
22001090 |
4 |
Transformation of quercitols into 4-methylenecyclohex-5-ene-1,2,3-triol derivatives, precursors for the chemical chaperones N-octyl-4-epi-ß-valienamine (NOEV) and N-octyl-ß-valienamine (NOV). |
Hokko Chemical Industry |
21974950 |
8 |
A fluorescent probe for GM1 gangliosidosis relatedß-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol. |
Industrial Research |
21862336 |
9 |
Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes. |
University Of Reading |
21546253 |
41 |
Docking and SAR studies of D- and L-isofagomine isomers as humanß-glucocerebrosidase inhibitors. |
University Of Toyama |
21370884 |
80 |
New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening. |
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas) |
24900289 |
155 |
Identification of Potent and Selective Glucosylceramide Synthase Inhibitors from a Library of N-Alkylated Iminosugars |
TBA |
19515568 |
1 |
Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging. |
Katholieke Universiteit Leuven |
| 37 |
Synthesis of a new inhibitor of α-fucosidase |
TBA |
| 5 |
Synthesis of C2-symmetrical polyhydroxyazepanes as inhibitors of glycosidases |
TBA |
18996021 |
1 |
1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors. |
Technische UniversitäT Graz |
15165148 |
13 |
Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana. |
Hokuriku University |
12502331 |
28 |
New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica. |
Hokuriku University |
11858756 |
25 |
New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii. |
Hokuriku University |
16603357 |
6 |
Flexible synthesis and biological evaluation of novel 5-deoxyadenophorine analogues. |
Université |
16481162 |
17 |
Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols. |
Technische UniversitäT Graz |
14505649 |
21 |
Synthesis and glycosidase inhibitory activity of some N-substituted 6-deoxy-5a-carba-beta-DL- and L-galactopyranosylamines. |
Keio University |
12161128 |
35 |
Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: new leads as selective beta-galactosidase inhibitors. |
Universidad De Sevilla |
10560746 |
10 |
Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. |
Institut De Chimie Organique Et Analytique (I.C.O.A.) |
10201849 |
3 |
Synthesis of alpha-C(1-->3)-mannopyranoside of N-acetylgalactosamine, a new beta-galactosidase inhibitor. |
Institut De Chimie Organique De L'Université |
30469042 |
9 |
Pharmaceutical significance of azepane based motifs for drug discovery: A critical review. |
Wuhan Institute Of Technology |
10021944 |
8 |
Specific, uncompetitive inhibition of beta-galactosidases by a 5,6-isopropylidenedioxyfuro[2,3-d]isoxazole-3-methanol derivative. |
Institut De Chimie Organique De L'Université |
26539626 |
5 |
Resveratrol-Related Polymethoxystilbene Glycosides: Synthesis, Antiproliferative Activity, and Glycosidase Inhibition. |
Universit£ |
25295392 |
30 |
Structure-activity relationship of highly potent galactonoamidine inhibitors toward ?-galactosidase (Aspergillus oryzae). |
University Of Arkansas |
19674908 |
4 |
Synthesis of pentopyranosyl-containing thiodisaccharides. Inhibitory activity against beta-glycosidases. |
Universidad De Buenos Aires |
30270003 |
13 |
4-epi-Isofagomine derivatives as pharmacological chaperones for the treatment of lysosomal diseases linked to ?-galactosidase mutations: Improved synthesis and biological investigations. |
Universit£ |
29674295 |
4 |
Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors. |
University Of Seville |
28692917 |
21 |
Tuning of ?-glucosidase and ?-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules. |
University Of Seville |
28844803 |
50 |
Picomolar inhibition of?-galactosidase (bovine liver) attributed to loop closure. |
University Of Arkansas |
28600215 |
15 |
A new type of pharmacological chaperone for G |
Graz University Of Technology |
29112434 |
7 |
N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer of?-Glucosidase Activity for the Treatment of Pompe Disease. |
Universit£ |
27305312 |
4 |
Capture-Tag-Release: A Strategy for Small Molecule Labeling of Native Enzymes. |
Fairfield University |
26364932 |
22 |
Structure and Inhibition of Microbiome ß-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. |
University Of North Carolina At Chapel Hill |
23775891 |
83 |
New insights into the pharmacological chaperone activity of c2-substituted glucoimidazoles for the treatment of Gaucher disease. |
Nankai University |