The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
25221666 |
20 |
Acyclic tethers mimicking subunits of polysaccharide ligands: selectin antagonists. |
Institut De Recherches Cliniques De Montr£Al (Ircm) |
23312943 |
166 |
Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase. |
Pfizer |
24900426 |
4 |
A new approach to explore the binding space of polysaccharide-based ligands: selectin antagonists. |
TBA |
17302397 |
113 |
Rational design of novel, potent small molecule pan-selectin antagonists. |
Revotar Biopharmaceuticals |
11405647 |
24 |
Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity. |
Ontogen |
9544210 |
46 |
Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269). |
Texas Biotechnology |
9784103 |
42 |
Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides. |
Kanebo |
9357520 |
18 |
Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides. |
Kanebo |
9379443 |
17 |
Sulfated galactocerebrosides as potential antiinflammatory agents. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
8632441 |
24 |
Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs. |
Institute Of Cancer Research |
8917642 |
4 |
Studies on selectin blocker. 3. Investigation of the carbohydrate ligand sialyl Lewis X recognition site of P-selectin. |
Kanebo |
8642564 |
12 |
Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders. |
New Drug Research Laboratory |
8544173 |
37 |
Rational design and synthesis of small molecule, non-oligosaccharide selectin inhibitors: (alpha-D-mannopyranosyloxy)biphenyl-substituted carboxylic acids. |
Texas Biotechnology |
11354355 |
6 |
Design and synthesis of a new sialyl Lewis X mimetic: how selective are the selectin receptors? |
Universit£ |
10969978 |
9 |
A solid-phase synthesis for beta-turn mimetics of sialyl Lewis X. |
Nippon Organon K.K. |
9873537 |
71 |
Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction. |
Scripps Research Institute |
20718494 |
7 |
Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury. |
Pfizer |
20171887 |
15 |
Synthesis of fluorinated C-mannopeptides as sialyl Lewisx mimics for E- and P-selectin inhibition. |
Universit£ |
9134746 |
2 |
Isolation and structure determination of sulfonoquinovosyl dipalmitoyl glyceride, a P-selectin receptor inhibitor from the alga Dictyochloris fragrans. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
| 8 |
Chemical and enzymatic synthesis of high-affinity selectin ligands |
TBA |
| 1 |
Design and synthesis of an α-mannosyl terpenoid as selective inhibitor of P-selectin |
TBA |
| 13 |
Synthesis and biological activity of novel sialyl-lewisX conjugates |
TBA |
17201409 |
50 |
2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[H]quinoline-4-carboxylic acid (PSI-697): identification of a clinical candidate from the quinoline salicylic acid series of P-selectin antagonists. |
Wyeth Research |
15974587 |
1 |
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin. |
Wyeth |
15936191 |
16 |
Sialyl Lewis(x) analogs based on a quinic acid scaffold as the fucose mimic. |
National Chemical Engineering Institute In Paris |
11527732 |
1 |
Drug design, synthesis, and evaluation of a non-sugar-based selectin antagonist. |
Organon K.K. |
9873724 |
21 |
Aryl C-glycosides: physiologically stable glycomimetics of sialyl Lewis X. |
Sankyo |
31376564 |
13 |
Cinnamamide: An insight into the pharmacological advances and structure-activity relationships. |
National Institute Of Pharmaceutical Education And Research (Niper) |
9022803 |
9 |
Selectin-ligand interactions revealed by molecular dynamics simulation in solution. |
Kanebo |
8676335 |
2 |
Carbohydrates in an acidic multivalent assembly: nanomolar P-selectin inhibitors. |
Lawrence Berkeley National Laboratories |