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23 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
1527792 52 Specific inhibition of HIV-1 protease by boronated porphyrins.EBI University of California
1635057 48 Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors.EBI Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.
3045320 37 Design of rat renin inhibitory peptides.EBI Massachusetts General Hospital
3275777 34 Design, structure-activity, and molecular modeling studies of potent renin inhibitory peptides having N-terminal Nin-For-Trp (Ftr): angiotensinogen congeners modified by P1-P1' Phe-Phe, Sta, Leu psi[CH(OH)CH2]Val or leu psi[CH2NH]Val substitutions.EBI Upjohn Company
3543358 96 Pepstatin analogues as novel renin inhibitors.EBI TBA
3906131 61 Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.EBI TBA
20731374 65 Direct renin inhibitors as a new therapy for hypertension.EBI Novartis Pharmaceuticals Corp
19615901 52 The P1N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin.EBI Nagasaki International University
 23 Novel low molecular renin inhibitors which show good oral blood pressure lowering effects in marmosetsEBI TBA
 3 CP-71,362, an unusually potent inhibitor of rat and dog reninEBI TBA
 1 Evaluation of the intestinal permeability and hepatic handling of peptidomimetic analogsEBI TBA
 12 MDL 74147, a novel selective and soluble inhibitor of human renin. Synthesis, structure-activity relationship, species and protease selectivities.EBI TBA
15081001 9 The discovery of structurally novel CCR1 antagonists derived from a hydroxyethylene peptide isostere template.EBI Pfizer Global Research and Development
8474102 29 Studies directed toward the design of orally active renin inhibitors. 2. Development of the efficacious, bioavailable renin inhibitor (2S)-2-benzyl-3- [[(1-methylpiperazin-4-yl)sulfonyl]propionyl]-3-thiazol-4-yl-L-alanine amide of (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane (A-725EBI Abbott Laboratories
8410992 35 Renin inhibitors containing a pyridyl amino diol derived C-terminus.EBI Hoechst AG
7932521 81 Nonpeptide renin inhibitors with good intraduodenal bioavailability and efficacy in dog.EBI Abbott Laboratories
3309313 48 Renin inhibitors. Dipeptide analogues of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond.EBI Abbott Laboratories
3302256 45 Analysis of structure-activity relationships in renin substrate analogue inhibitory peptides.EBI TBA
3137345 18 Synthesis and biological activity of some transition-state inhibitors of human renin.EBI Ciba-Geigy Limited
3127587 31 New human renin inhibitors containing an unnatural amino acid, norstatine.EBI Kissei Pharmaceutical Co., Ltd.
2202829 18 Inhibitors of human renin. Cyclic peptide analogues containing a D-Phe-Lys-D-Trp sequence.EBI ICI Pharmaceuticals
2197413 8 Potent renin inhibitory peptides containing hydrophilic end groups.EBI Upjohn Company
1738148 16 Renin inhibitory pentols showing improved enteral bioavailability.EBI Hoechst AG