BindingDB logo
myBDB logout

40 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
9171867 16 Dual metalloprotease inhibitors: mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
 12 Dual metalloprotease inhibitors.v. Utilization of bicyclic azepinonethiazolidines and azepinonetetrahydrothiazines in constrained peptidomimetics of mercaptoacyl dipeptidesEBI TBA
 36 Dual metalloprotease inhibitors. IV. Utilization of thiazepines and thiazines as constrained peptidomimetic surrogates in mercaptoacyl dipeptidesEBI TBA
12852763 20 Computer-aided selection of potential antihypertensive compounds with dual mechanism of action.EBI Institute of Biomedical Chemistry of Russian Academy of Medical Sciences
10669576 65 Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.EBI Novartis Institute for Biomedical Research
10669559 180 Protease inhibitors: current status and future prospects.EBI University of Queensland
10882358 62 Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.EBI F. Hoffmann-La Roche Ltd.
8544178 46 New alpha-thiol dipeptide dual inhibitors of angiotensin-I converting enzyme and neutral endopeptidase EC 3.4.24.11.EBI CIBA-GEIGY Corporation
8120868 22 N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors.EBI CIBA-GEIGY Corporation
8254611 11 Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor.EBI CIBA-GEIGY Corporation
2585440 34 Enkephalinase inhibitors. 1. 2,4-Dibenzylglutaric acid derivatives.EBI CIBA-GEIGY Corporation
2993614 21 Synthesis and biological evaluation of phosphonamidate peptide inhibitors of enkephalinase and angiotensin-converting enzyme.EBI TBA
3897541 27 New bidentates as full inhibitors of enkephalin-degrading enzymes: synthesis and analgesic properties.EBI TBA
 22 Design and synthesis of phosphinic acids that triply inhibit endothelin converting enzyme, angiotensin converting enzyme and neutral endopeptidase 24.11EBI TBA
 18 Highly potent and selective inhibitors of endothelin converting enzymeEBI TBA
 21 Potent inhibitors of neutral endopeptidase. 2-Biphenyl- methylglutaric acid amide derivativesEBI TBA
 20 4-Substituted proline derivatives that inhibit angiotensin converting enzyme and neutral endopeptidase 24.11.EBI TBA
 46 Mercaptoacyl dipeptides as dual inhibitors of angiotensin-converting enzyme and neutral endopeptidase. Preliminary structure-activity studiesEBI TBA
 20 Aminophosphonate endothelin converting enzyme inhibitors: potency-enhancing and selectivity-improving modifications of phosphoramidonEBI TBA
 3 The synthesis of aminobenzazepinones as anti-phenylalanine dipeptide mimics and their use in nep inhibitionEBI TBA
 5 Design and synthesis of a new class of conformationally constrained inhibitors to probe the active sites of thermolysine and neutral endopeptidase 24.11EBI TBA
 16 Synthesis of constrained thiorphan analogs as inhibitors of neutral endopeptidaseEBI TBA
 28 α-Mercaptoacyl dipeptides that inhibit angiotensin converting enzyme and neutral endopeptidase 24.11EBI TBA
 3 Non-peptidic inhibitors of neutral endopeptidase 24.11 2. Design and pharmacology of orally active phosphonate prodrugsEBI TBA
 26 Non-peptidic inhibitors of neutral endopeptidase 24.11 1. Discovery and optimization of potencyEBI TBA
 6 The effect of heteroatom substitution on a series of phosphonate inhibitors of neutral endopeptidase 24.11EBI TBA
 6 Gem-cycloalkyl substituted thiol inhibitors of neutral endopeptidase 24.11. Synthesis via nucleophilic opening of 2,2-spiro-β-lactonesEBI TBA
17070062 16 Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder.EBI Pfizer Global Research and Development
16821800 96 Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Synthesis and activity of functionalized glutaramides.EBI Pfizer Global Research and Development
10698448 23 N-formyl hydroxylamine containing dipeptides: generation of a new class of vasopeptidase inhibitors.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
9925736 16 Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides.EBI The Bristol-Myers Squibb Pharmaceutical Research Institute
9484512 130 Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives.EBI Shionogi & Co., Ltd.
8558518 38 Dual metalloprotease inhibitors. 6. Incorporation of bicyclic and substituted monocyclic azepinones as dipeptide surrogates in angiotensin-converting enzyme/neutral endopeptidase inhibitors.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
8496905 6 Synthesis and analgesic effects of N-[3-[(hydroxyamino) carbonyl]-1-oxo-2(R)-benzylpropyl]-L-isoleucyl-L-leucine, a new potent inhibitor of multiple neurotensin/neuromedin N degrading enzymes.EBI CCIPE-Faculté de Pharmacie
8360888 12 Application of a conformationally restricted Phe-Leu dipeptide mimetic to the design of a combined inhibitor of angiotensin I-converting enzyme and neutral endopeptidase 24.11.EBI Marion Merrell Dow Research Institute
8254612 8 Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors.EBI CIBA-GEIGY Corporation
7752193 43 Dicarboxylic acid dipeptide neutral endopeptidase inhibitors.EBI CIBA-GEIGY Corporation
3517331 10 1H NMR configurational correlation for retro-inverso dipeptides: application to the determination of the absolute configuration of"enkephalinase" inhibitors. Relationships between stereochemistry and enzyme recognition.EBI TBA
1738153 45 A novel class of enkephalinase inhibitors containing a C-terminal sulfo group.EBI Dainippon Pharmaceutical Co., Ltd.