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65 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
1548679 20 Development of high-affinity 5-HT3 receptor antagonists. 2. Two novel tricyclic benzamides.EBI Rh£ne-Poulenc Rorer Central Research
8410977 43 2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists.EBI Syntex Research
1578478 30 Novel antagonists of the 5-HT3 receptor. Synthesis and structure-activity relationships of (2-alkoxybenzoyl)ureas.EBI Wyeth Research
1552497 38 Novel 5-HT3 antagonists: indol-3-ylspiro(azabicycloalkane-3,5'(4'H)-oxazoles).EBI Merck Sharp and Dohme Research Laboratories
1992112 53 Novel 5-HT3 antagonists. Indole oxadiazoles.EBI Merck Sharp and Dohme Research Laboratories
8642566 277 Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines.EBI Universit£ de Caen
7752204 98 Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors.EBI Merck Sharp& Dohme Research Laboratories
8496922 92 Synthesis and serotonergic activity of 5-(oxadiazolyl)tryptamines: potent agonists for 5-HT1D receptors.EBI Merck Sharp and Dohme Research Laboratories
2342053 20 Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site.EBI Merrell Dow Research Institute
 12 Quaternised renzapride as a potent and selective 5-HT4 receptor agonistEBI TBA
16451077 86 Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.EBI Pfizer Inc.
15715459 3 Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.EBI Pfizer Inc.
15887964 47 Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties.EBI Universit£ di Siena
15482914 25 Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.EBI Pfizer Inc.
12593651 107 Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.EBI Dainippon Pharmaceutical Co. Ltd.
10229626 66 Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.EBI Universit£ di Siena
10585211 62 Benzimidazole derivatives. 2. Synthesis and structure-activity relationships of new azabicyclic benzimidazole-4-carboxylic acid derivatives with affinity for serotoninergic 5-HT(3) receptors.EBI Universidad Complutense
10425096 80 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.EBI FAES, S.A.
9513601 53 Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives.EBI Universit£ di Siena
9464362 19 5-HT3 antagonists derived from aminopyridazine-type muscarinic M1 agonists.EBI Universit£ Louis Pasteur
9685241 2 Benzoxazole derivatives as novel 5-HT3 receptor partial agonists in the gut.EBI Pharmaceutical Research Center
9046352 86 New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors.EBI CNRS-BIOCIS
9357534 49 Novel and highly potent 5-HT3 receptor agonists based on a pyrroloquinoxaline structure.EBI Universit£ di Siena
9341912 43 Phenylimidazolidin-2-one derivatives as selective 5-HT3 receptor antagonists and refinement of the pharmacophore model for 5-HT3 receptor binding.EBI Pharmacia& Upjohn
7629808 64 Novel, potent, and selective 5-HT3 receptor antagonists based on the arylpiperazine skeleton: synthesis, structure, biological activity, and comparative molecular field analysis studies.EBI Universit£ di Siena
8176710 24 Synthesis of 2-piperazinylbenzothiazole and 2-piperazinylbenzoxazole derivatives with 5-HT3 antagonist and 5-HT4 agonist properties.EBI CIFA Universidad de Navarra
8496941 23 5-HT3 receptor antagonists. 2. 4-Hydroxy-3-quinolinecarboxylic acid derivatives.EBI Kyowa Hakko Kogyo Company, Ltd.
8410988 12 Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives.EBI Universidad de Navarra
1573641 60 SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype.EBI Searle Research and Development
1312602 18 Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides.EBI Rh£ne-Poulenc Rorer Central Research
1479589 36 5-HT3 receptor antagonists. 1. New quinoline derivatives.EBI Kyowa Hakko Kogyo Co.
1695682 41 Synthesis of a new class of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid derivatives as highly potent 5-HT3 receptor antagonists.EBI Istituto De Angeli
2362270 3 5-Hydroxytryptamine (5-HT3) receptor antagonists. 1. Indazole and indolizine-3-carboxylic acid derivatives.EBI Beecham Pharmaceuticals Research Division
2258903 23 Synthesis and biochemical evaluation of tritium-labeled 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxa mide, a useful radioligand for 5HT3 receptors.EBI Lilly Research Laboratories
2296012 10 Aromatic thiazole derivatives: structurally novel and selective serotonin-3 receptor antagonists.EBI Pfizer Central Research
2874226 27 Buspirone analogues. 2. Structure-activity relationships of aromatic imide derivatives.EBI TBA
11755351 24 Synthesis and pharmacology of isoquinuclidine derivatives as 5-HT(3) ligands.EBI Universidad de Alcal£
9871571 44 A novel series of N-(hexahydro-1,4-diazepin-6-yl) and N-(hexahydroazepin- 3-yl)benzamides with high affinity for 5-HT3 and dopamine D2 receptors.EBI Dainippon Pharmaceutical Co., Ltd.
 63 Serotoninergic 5-HT3 and 5-HT4 receptor activities of dihydrobenzofuran carboxylic acid derivativesEBI TBA
 26 Novel benzimidazole-4-carboxylic acid derivatives as potent and selective 5-HT3 receptor ligandsEBI TBA
 24 Synthesis and pharmacological activity of a macrocyclic benzamideEBI TBA
 8 N-chloromethyl quinuclidinium derivatives: A new class of irreversible ligands for 5-HT3 receptors.EBI TBA
 25 Pyrazolo[1,5-a]pyridines and pyrazolo[1,5-b]pyridazines as 5ht3-antagonistsEBI TBA
 7 Azaheteroaromatic ethers as carbonyl bioisosteres. Synthesis and evaluation of a novel class of 5-HT3 receptor antagonistsEBI TBA
 21 Serotonin 5-HT4 agonist activity of a series of meso-azanoradamantane benzamidesEBI TBA
 35 Design of a potent 5-HT4 receptor agonist with nanomolar affinityEBI TBA
 18 Derivatives of quinuclidine as 5-HT3 receptor antagonists: influence of an additional carbonyl group on the recognition of chirality by the receptor.EBI TBA
 18 Derivatives of naphthalimide: new potent conformationally restricted antagonists of 5-HT3 receptors.EBI TBA
15341484 159 Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.EBI Merck KGaA
15084129 52 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.EBI Università di Bari
12951088 22 Design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.EBI Universidad Complutense
12109911 47 Synthesis and pharmacological testing of 1,2,3,4,10,14b-hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and its enantiomers in comparison with the two antidepressants mianserin and mirtazapine.EBI University Center for Pharmacy
11934576 85 Synthesis and pharmacological evaluation of 6-piperidino- and 6-piperazinoalkyl-2(3H)-benzothiazolones as mixed sigma/5-HT(1A) ligands.EBI Université de Lille 2
10543880 63 Pyrroloquinoxaline derivatives as high-affinity and selective 5-HT(3) receptor agonists: synthesis, further structure-activity relationships, and biological studies.EBI Universita' degli Studi di Salerno
9873388 24 Synthesis of N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)nicotinamides and their affinities for 5-HT3 and dopamine D2 receptors.EBI Dainippon Pharmaceutical Co., Ltd.
9046348 45 [[(Arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands.EBI Università di Catania
8246239 84 Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives.EBI Solvay Duphar B.V.
8071931 20 5-(Nonyloxy)tryptamine: a novel high-affinity 5-HT1D beta serotonin receptor agonist.EBI Medical College of Virginia/Virginia Commonwealth University
8064797 118 Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors.EBI Vanderbilt University
6581313 2 Synthesis and evaluation of a novel series of N,N-dimethylisotryptamines.EBI TBA