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29 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28169167 137 Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes asa7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
27818109 30 Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol asa42-nicotinic acetylcholine receptor ligands.EBI Universit£ degli Studi di Milano
26706350 48 Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for thea34 nicotinic acetylcholine receptor subtype.EBI Universit£ degli Studi di Milano
26142318 36 The twin drug approach for novel nicotinic acetylcholine receptor ligands.EBI University of Hawai'i at Hilo
24050653 59 Derivatives of dibenzothiophene for positron emission tomography imaging ofa7-nicotinic acetylcholine receptors.EBI The Johns Hopkins University School of Medicine
24649848 47 Discovery of a potent and selectivea34 nicotinic acetylcholine receptor antagonist from ana-conotoxin synthetic combinatorial library.EBI Torrey Pines Institute for Molecular Studies
24274400 28 Scaffold ranking and positional scanning utilized in the discovery of nAChR-selective compounds suitable for optimization studies.EBI Torrey Pines Institute for Molecular Studies
24200193 32 Characterization of a novela-conotoxin TxID from Conus textile that potently blocks rata34 nicotinic acetylcholine receptors.EBI Hainan University
24156938 12 The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor (nAChR) ligands. Part 1: the influence of different hydrogen bond acceptor systems on alkyl and (hetero)aryl substituents.EBI University of Bonn
24035337 10 2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character.EBI Virginia Commonwealth University
23602445 23 An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.EBI UCL School of Pharmacy
23641311 38 From a42 Nicotinic Ligands to the Discovery of s1 Receptor Ligands: Pharmacophore Analysis and Rational Design.EBI TBA
22749278 16 Diazaspirocyclic compounds as selective ligands for thea4ß2 nicotinic acetylcholine receptor.EBI Targacept, Inc.
24936233 8 Discovery of Novel a42 Neuronal Nicotinic Receptor Modulators through Structure-Based Virtual Screening.EBI TBA
19954975 27 Structure-activity relationships of N-substituted ligands for the alpha7 nicotinic acetylcholine receptor.EBI Abbott Laboratories
16033252 84 Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.EBI The Danish University of Pharmaceutical Sciences
12801235 5 Synthesis and biological evaluation of 18-methoxycoronaridine congeners. Potential antiaddiction agents.EBI University of Vermont
9435889 70 Neuronal nicotinic acetylcholine receptors as targets for drug discovery.EBI Abbott Laboratories
8765504 34 (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors.EBI SIBIA Neurosciences Inc.
15050614 10 Activity of alpha7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes.EBI University of Florida
15203153 23 Structure activity studies of ring E analogues of methyllycaconitine. Part 2: Synthesis of antagonists to the alpha3beta4* nicotinic acetylcholine receptors through modifications to the ester.EBI Ohio University
21319801 54 Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine.EBI Research Triangle Institute
21397497 18 Discovery of non-peptide, small molecule antagonists ofa9a10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.EBI University of Kentucky
20509659 182 Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation.EBI Barrow Neurological Institute
16821801 35 Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship.EBI Pfizer Global Research & Development
15771418 38 Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing beta2 subunits.EBI University of Illinois at Chicago
14684341 15 Synthesis and nicotinic receptor activity of a hydroxylated tropane.EBI University of Wollongong
9873508 3 Conformationally restricted analogues of nicotine and anabasine.EBI SIBIA Neurosciences Inc.