BindingDB logo
myBDB logout

41 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27876250 60 Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CHEBI Jagiellonian University Medical College
24960305 11 Calcitonin gene-related peptide receptor antagonists: new therapeutic agents for migraine.EBI Merck Research Laboratories
24794104 6 Serendipitous oxidation product of BIBN4096BS: a potent CGRP receptor antagonist.EBI Bristol-Myers Squibb Company
24405707 100 Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists.EBI Vertex Pharmaceuticals Inc.
23993336 24 Preparation of imidazoles as potent calcitonin gene-related peptide (CGRP) antagonists.EBI Bristol-Myers Squibb
23632269 9 Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery.EBI Bristol-Myers Squibb R&D
23402880 51 The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2.EBI Bristol-Myers Squibb Research& Development
20097071 39 Potent oxadiazole CGRP receptor antagonists for the potential treatment of migraine.EBI GlaxoSmithKline
23153230 8 Discovery of (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): an oral calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraine.EBI Bristol-Myers Squibb Research& Development
22732695 26 Design and synthesis of potent antagonists containing rigid spirocyclic privileged structures for the CGRP receptor.EBI Bristol-Myers Squibb R&D
22727645 42 The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 1.EBI Bristol-Myers Squibb Research& Development
22607672 28 MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in rats.EBI Merck Research Laboratories
22429470 75 Calcitonin gene-related peptide (CGRP) receptor antagonists: pyridine as a replacement for a core amide group.EBI Bristol-Myers Squibb Research& Development
22429471 64 Calcitonin gene-related peptide (CGRP) receptor antagonists: novel aspartates and succinates.EBI Bristol-Myers Squibb Research& Development
19010673 62 The discovery of highly potent CGRP receptor antagonists.EBI Merck& Co
18039571 68 Calcitonin gene-related peptide (CGRP) receptor antagonists: investigations of a pyridinone template.EBI Merck Research Laboratories
 6 Synthesis of -helix substituted analogs of calcitonin gene-related peptideEBI TBA
21251825 91 Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918.EBI Merck Research Laboratories
20850973 12 Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chirality.EBI Merck& Co.
20299218 52 Identification of potent, highly constrained CGRP receptor antagonists.EBI Merck& Co.
19818613 43 Optimization of azepanone calcitonin gene-related peptide (CGRP) receptor antagonists: development of novel spiropiperidines.EBI Merck Research Laboratories
19703767 34 Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibility.EBI Merck& Co.
19577468 33 The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.EBI Merck Research Laboratories
 14 Quinine analogs as non-peptide calcitonin gene-related peptide (CGRP) receptor antagonistsEBI TBA
19467597 13 Carbamates as potent calcitonin gene-related peptide antagonists with improved solution stability.EBI Bristol-Myers Squibb Research and Development
18947992 88 Potent benzimidazolone-based CGRP receptor antagonists.EBI Merck & Co.
18665579 21 Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficEBI Bristol-Myers Squibb Research & Development
17929795 79 Potent, orally bioavailable calcitonin gene-related peptide receptor antagonists for the treatment of migraine: discovery of N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1- (2,2,2-trifluoroethyl)azepan-3-yl]-4- (2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin- 1-yl)piperidine-1-carboxamide (MK-0974).EBI Merck Research Laboratories
17319653 10 Calcitonin gene-related peptide analogues with aza and indolizidinone amino acid residues reveal conformational requirements for antagonist activity at the human calcitonin gene-related peptide 1 receptor.EBI Université de Montréal
17027263 42 Identification of novel, orally bioavailable spirohydantoin CGRP receptor antagonists.EBI Merck Research Laboratories
16889959 86 Benzodiazepine calcitonin gene-related peptide (CGRP) receptor antagonists: optimization of the 4-substituted piperidine.EBI Merck Research Laboratories
16161996 30 Development of human calcitonin gene-related peptide (CGRP) receptor antagonists. 1. Potent and selective small molecule CGRP antagonists. 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-l-lysyl]-4-(4-pyridinyl)piperazine: the first CGRP antagonistEBI Boehringer Ingelheim Pharma GmbH & Co. KG
9438028 63 From micromolar to nanomolar affinity: a systematic approach to identify the binding site of CGRP at the human calcitonin gene-related peptide 1 receptor.EBI ETH Zürich
1319490 27 Structure-activity study of hCGRP8-37, a calcitonin gene-related peptide receptor antagonist.EBI Université du Québec