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44 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26296911 11 3-Benzamides and 3,4,5-trimethoxyphenyl amines as calcium channel blockers.EBI Ewha Womans University
24205976 2 Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).EBI Research& Development, Janssen Pharmaceutical Companies of Johnson& Johnson
23876987 4 Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and neuropathic pain.EBI Neuroscience Research, AbbVie, 1 N Waukegan Road, North Chicago, IL 60064, United States. xenia.b.searle@abbvie.com
23639535 17 Modular, efficient synthesis of asymmetrically substituted piperazine scaffolds as potent calcium channel blockers.EBI University of British Columbia
23098566 17 Aminopiperidine sulfonamide Cav2.2 channel inhibitors for the treatment of chronic pain.EBI Merck Research Laboratories
22626552 2 Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca²¿ channel blockers with analgesic activity.EBI Abbott Laboratories
22560585 16 Discovery and evaluation of selective N-type calcium channel blockers: 6-unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives.EBI Ajinomoto Pharmaceuticals Co. Ltd
19388676 21 Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.EBI Johnson& Johnson Pharmaceutical Research& Development
17483457 58 A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.EBI Abbott Laboratories
15537361 9 Design, synthesis, and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain.EBI Universit£ di Firenze
11000000 1 (S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.EBI Pfizer Global Research and Development
22177784 2 In vivo evaluation of oral anti-tumoral effect of 3,4-dihydroquinazoline derivative on solid tumor.EBI Kyung Hee University
21316226 12 Pyridyl amides as potent inhibitors of T-type calcium channels.EBI Merck Research Laboratories
21195616 26 A potent and selective indole N-type calcium channel (Ca(v)2.2) blocker for the treatment of pain.EBI Merck Research Laboratories
20934333 2 Design, syntheses, and SAR of 2,8-diazaspiro[4.5]decanones as T-type calcium channel antagonists.EBI Icagen, Inc.
20855211 91 Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives.EBI Abbott Laboratories
20382529 13 Synthesis and biological evaluation of 1,4-diazepane derivatives as T-type calcium channel blockers.EBI Institute of Science and Technology
19683451 12 Omega-conotoxin GVIA mimetics based on an anthranilamide core: effect of variation in ammonium side chain lengths and incorporation of fluorine.EBI The University of Queensland
19362476 13 Low molecular weight non-peptide mimics of omega-conotoxin GVIA.EBI CSIRO Molecular and Health Technologies
17134896 41 Synthesis and SAR of novel 2-arylthiazolidinones as selective analgesic N-type calcium channel blockers.EBI Ionix Pharmaceuticals Ltd
16722655 28 Discovery of a novel, orally active, small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist.EBI Pfizer Global Research & Development
12161113 8 L-Cysteine based N-type calcium channel blockers: structure-activity relationships of the C-terminal lipophilic moiety, and oral analgesic efficacy in rat pain models.EBI Minase Research Institute
11958993 23 Structure-activity study of L-cysteine-based N-type calcium channel blockers: optimization of N- and C-terminal substituents.EBI Minase Research Institute
11514140 17 Structure-activity study and analgesic efficacy of amino acid derivatives as N-type calcium channel blockers.EBI no Pharmaceutical Co., Ltd.
10714496 2 Design and biological evaluation of non-peptide analogues of omega-conotoxin MVIIA.EBI Parke-Davis Neuroscience Research Centre
10514294 15 Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.EBI Warner-Lambert Company
10476886 14 Structure-activity relationship at the proximal phenyl group in a series of non-peptidyl N-type calcium channel antagonists.EBI Parke-Davis Pharmaceutical Research
10476885 10 Synthesis and biological activity of substituted bis-(4-hydroxyphenyl)methanes as N-type calcium channel blockers.EBI Warner-Lambert Company
10465535 14 Structure-activity relationship of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers.EBI Warner-Lambert Company
10406647 30 Multiple parallel synthesis of N,N-dialkyldipeptidylamines as N-type calcium channel blockers.EBI Warner-Lambert Company
10328297 13 Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers.EBI Warner-Lambert Company
10206559 18 N,N-dialkyl-dipeptidylamines as novel N-type calcium channel blockers.EBI Warner-Lambert Company
9873552 12 Synthesis and structure-activity relationship of substituted 1,2,3,4-tetrahydroisoquinolines as N-type calcium channel blockers.EBI Warner-Lambert Company
15131245 86 SR147778 [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of the CB1 cannabinoid receptor: biochemical and pharmacological characterization.BDB Sanofi-Synthelabo Recherche
12721338 61 N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties.BDB Pudue Pharma Discovery Research
12431845 84 Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder.BDB Lilly Research Laboratories
11750180 139 Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors.BDB Lilly Research Laboratories
9454810 72 SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.BDB Sanofi Recherche
8887981 72 A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand.BDB Abbott Laboratories
7518514 46 (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization.BDB Abbott Laboratories