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103 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28111158 100 Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties.EBI Abant Izzet Baysal University
27919611 60 Discovery of 4-sulfamoyl-phenyl-▀-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors.EBI National Institute of Pharmaceutical Education and Research (NIPER)
27876475 68 Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII.EBI Dumlupinar University
27144971 60 PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas.EBI Temple University School of Pharmacy
27172398 20 An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C.EBI Griffith University
27298005 92 Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII.EBI Dumlupinar University
26498394 105 Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters.EBI Universit£ degli Studi di Firenze
26498393 116 New natural product carbonic anhydrase inhibitors incorporating phenol moieties.EBI Aristotle University of Thessaloniki
26347950 32 Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.EBI Griffith University
25468040 77 Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.EBI TBA
25358084 143 Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.EBI Vilnius University
24689792 54 Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.EBI Griffith University
23010455 108 Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.EBI Universidad Nacional de La Plata
23067387 105 Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.EBI Universit£ di Pisa
22687439 51 Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B.EBI Atat£rk University
22487176 109 Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.EBI Universit£ degli Studi di Cagliari
21211980 47 Characterization and anions inhibition studies of ana-carbonic anhydrase from the teleost fish Dicentrarchus labrax.EBI Ondokuz Mayis University
20674354 79 Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.EBI Universit£ degli Studi di Firenze
20605094 91 Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.EBI University of Florida
20472429 80 Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.EBI Istituto di Biostrutture e Bioimmagini-CNR
20363633 67 Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: structure-based drug design, synthesis, and biological evaluation.EBI Pfizer Global Research and Development
20185318 132 Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.EBI Universit£ degli Studi di Firenze
19911821 273 Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.EBI Universita degli Studi di Firenze
19854054 18 Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma.EBI NicOx Research Institute
20028100 78 The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Firenze
19269822 75 Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions.EBI Universit£ degli Studi di Firenze
19186056 60 A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.EBI Universit£ degli Studi di Firenze
18990571 65 Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
18359629 84 Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.EBI Istituto di Biostrutture e Bioimmagini-CNR
17475500 130 Carbonic anhydrases as targets for medicinal chemistry.EBI Universit£ degli Studi di Firenze
17376683 63 Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
17314045 11 Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.EBI Universit£ degli Studi di Firenze
16290146 30 Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II"selective" inhibitor celecoxib.EBI Istituto di Biostrutture e Bioimmagini-CNR
15686931 84 Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.EBI Universit£ degli Studi di Firenze
15664814 55 Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.EBI Universit£ degli Studi di Firenze
15501038 68 Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.EBI Universit£ degli Studi di Firenze
15357993 82 Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions.EBI Universit£ degli Studi di Firenze
15139757 105 Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.EBI Universit£ degli Studi di Firenze
11906288 713 Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.EBI Universit£ degli Studi di Firenze
11784136 100 Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties.EBI University of Namur
11123998 141 Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects.EBI Universit£ degli Studi di Firenze
11087579 465 Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged duration of action.EBI Universit£ degli Studi di Firenze
10479300 383 Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.EBI Universit£ degli Studi
10411484 176 Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?EBI Universit£ degli Studi
15012984 192 Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.EBI Slovak Academy of Sciences
14698154 26 Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.EBI Bruker-AXS s.r.l.
14684331 24 Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.EBI Universit£ degli Studi di Firenze
12643899 127 Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.EBI Universit£ degli Studi di Firenze
12617904 46 Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.EBI Universit£ degli Studi di Firenze
14611846 101 Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.EBI Universit£ degli Studi
12039560 377 Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.EBI Universit£ degli Studi di Firenze
11229775 192 Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties.EBI Universit£ degli Studi
11425561 197 Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties.EBI Universit£ degli Studi
10762051 66 Carbonic anhydrase inhibitors: topical sulfonamide antiglaucoma agents incorporating secondary amine moieties.EBI Universit£ degli Studi
10843231 129 Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV.EBI Universit£ degli Studi
22365761 144 New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.EBI Universit£ degli Studi di Firenze
22245047 135 Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI.EBI Ondokuz Mayis University
22230050 82 Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives.EBI Artvin£oruh University
21821413 65 Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
21515057 153 Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.EBI Universit£ degli Studi di Firenze
21549597 71 Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.EBI U.O. Oculistica Az. USL 3
21377369 60 Purification and inhibition studies with anions and sulfonamides of ana-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.EBI Universit£ degli Studi di Firenze
20590092 273 Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.EBI Universita degli Studi di Firenze
19527930 53 The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.EBI University of Tampere and Tampere University Hospital
19121582 15 Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions.EBI MC-98000 Princ
16759856 9 N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors.EBI Università degli Studi di Firenze
15780631 55 Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with complex fluorides, chlorides and cyanides.EBI Università degli Studi di Firenze
15745821 21 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates.EBI Université Montpellier II
15664815 45 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates.EBI Università degli Studi di Firenze
15501037 27 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet.EBI Università degli Studi di Milano
15081040 4 Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide.EBI Bruker-AXS s.r.l.
12873509 4 Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one?EBI Università degli Studi di Firenze
10649985 390 Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes.EBI Università degli Studi
23914927 24 Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies.BDB University of Calgary
22299585 46 Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes.BDB Ege University
22299576 44 Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors.BDB Ecole Nationale SupÚrieure de Chimie de Montpellier
22299577 12 Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII.BDB UniversitÓ di Firenze
22168126 43 Carbonic anhydrase inhibitors: in vitro inhibition of a isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids.BDB Ondokuz Mayis University
22145694 64 Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity.BDB Agri Ibrahim ăešen University
22050606 36 a-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters.BDB Dumlupinar University
15499999 35 Benzolamide is not a membrane-impermeant carbonic anhydrase inhibitor.BDB Università degli Studi di Firenze
11916140 21 Carbonic anhydrase activity modulators: synthesis of inhibitors and activators incorporating 2-substituted-thiazol-4-yl-methyl scaffolds.BDB Università degli Studi
19703035 60 Which carbonic anhydrases are targeted by the antiepileptic sulfonamides and sulfamates?BDB Istituto di Biostrutture e Bioimmagini-CNR
19731956 72 Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors.BDB CNR
19119014 12 Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference.BDB Universita degli Studi di Firenze
19128966 80 Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions.BDB Universita degli Studi di Firenze
18579385 132 Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid.BDB Universita degli Studi di Firenze
18819811 195 Carbonic anhydrase inhibitors: synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides.BDB Istanbul University
18374572 100 Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.BDB Universita degli Studi di Firenze
18640037 48 Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD 486019 with twelve mammalian carbonic anhydrase isoforms: Kinetic and X-ray crystallographic studies.BDB Universita degli Studi di Firenze
14971907 180 Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides.BDB Universita degli Studi di Firenze
15084132 88 Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.BDB Canadian Institutes of Health Research
14736236 20 Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.BDB University of Marburg
17125255 77 Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.BDB Universite Montpellier II
12747790 171 Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.BDB University of Agricultural Sciences and Veterinary Medicine
10882008 93 2H-Thieno[3,2-e]- and [2,3-e]-1,2-thiazine-6-sulfonamide 1,1-dioxides as ocular hypotensive agents: synthesis, carbonic anhydrase inhibition and evaluation in the rabbit.BDB Alcon Research, Ltd.
11020282 512 Carbonic anhydrase and matrix metalloproteinase inhibitors: sulfonylated amino acid hydroxamates with MMP inhibitory properties act as efficient inhibitors of CA isozymes I, II, and IV, and N-hydroxysulfonamides inhibit both these zinc enzymes.BDB Universita degli Studi