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228 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28065499 84 Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors.EBI Kurukshetra University
28024887 52 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations.EBI Riga Technical University
27939347 52 Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.EBI Universit£ degli Studi di Firenze
27933963 60 Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations.EBI Universit£ degli Studi di Firenze
27144971 60 PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas.EBI Temple University School of Pharmacy
27290692 18 N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition.EBI Universit£ degli Studi di Firenze
27172398 20 An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C.EBI Griffith University
27316543 24 Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Firenze
27234893 36 Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.EBI Cairo University
27166574 52 Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII.EBI Kurukshetra University
27137360 100 Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII.EBI Kurukshetra University
26805033 426 Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.EBI Uppsala University
26875933 72 Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma.EBI DAIS
26840366 72 Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII.EBI Egyptian Russian University
26741028 100 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.EBI Universit£ de Reims Champagne-Ardenne
26810836 28 Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111.EBI University of Florida College of Medicine
26810710 116 A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms.EBI 'G. D'Annunzio' University of Chieti-Pescara
26688270 104 Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins.EBI Universit£ degli Studi di Firenze
26803577 92 Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII.EBI Harran University
26520662 45 Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives.EBI Balikesir University
26497049 110 Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors.EBI Sapienza Universit£ di Roma
26498394 105 Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters.EBI Universit£ degli Studi di Firenze
26408817 69 Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII.EBI Egyptian Russian University
26432607 60 Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII.EBI Universit£ degli Studi di Firenze
26422787 68 Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII.EBI Dumlupinar University
26347950 32 Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.EBI Griffith University
26319622 12 Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents.EBI Universit£ degli Studi di Firenze
26276436 45 Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms.EBI Universit£ degli Studi di Messina
26233435 76 Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity.EBI University of Cagliari
26264840 104 Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies.EBI 'G. D'Annunzio' University of Chieti-Pescara
26160114 101 Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms.EBI Saint Petersburg State University
26191373 52 Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series.EBI Institut des Biomol£cules Max Mousseron (IBMM) UMR 5247 CNRS-ENSCM-Universit£ de Montpellier
26233796 68 Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties.EBI University of Cagliari
26203869 18 Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates.EBI University of Florida
26105196 52 Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.EBI Kurukshetra University
26073006 56 New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII.EBI University of Cagliari
26048024 84 Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.EBI Jazan University
26088336 96 5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII.EBI University of Belgrade
25921266 48 New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors.EBI Siedlce University of Natural Sciences and Humanities
26007302 56 New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies.EBI University of Chieti-Pescara
25875209 60 6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.EBI Latvian Institute of Organic Synthesis
25913118 95 Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII.EBI Harran University
25912674 52 Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives.EBI Cairo University
25553540 6 1,3,4-Thiadiazoles: a potent multi targeted pharmacological scaffold.EBI University of Mississippi
25846066 88 Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.EBI Universit£ degli Studi di Firenze
25766630 100 A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects.EBI Universit£ degli Studi di Firenze
25757603 79 New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity.EBI Siedlce University of Natural Sciences and Humanities
25753329 56 Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action.EBI Latvian Institute of Organic Synthesis
25147616 92 Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry.EBI Universit£ di Sassari
25050167 40 Carbonic anhydrase inhibitors: design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives.EBI Bharati Vidyapeeth's College of Pharmacy
25027802 56 Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies.EBI Sapienza University of Rome
25022971 124 Furazan and furoxan sulfonamides are stronga-carbonic anhydrase inhibitors and potential antiglaucoma agents.EBI Universit£ degli Studi di Torino
25019479 96 Cyclic tertiary sulfamates: selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives.EBI Sapienza University of Rome
24948563 44 Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors.EBI University of Perugia
25468040 77 Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.EBI TBA
25456084 100 4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII.EBI Kurukshetra University
25442309 120 Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds.EBI King Saud University
25438758 44 Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: towards new carbonic anhydrase glycoinhibitors.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
25358084 143 Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.EBI Vilnius University
25358036 64 A class of 4-sulfamoylphenyl-¿-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.EBI Universit£ degli Studi di Firenze
25310626 80 Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.EBI Universit£ degli Studi di Firenze
25267005 70 Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones.EBI Universit£ degli Studi di Firenze
25255434 84 Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling.EBI King Saud University
25254302 44 Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates.EBI Griffith University
25156300 48 Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.EBI Universidad Nacional de La Plata
24878360 76 Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties.EBI King Saud University
24871996 124 Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.EBI Medical University of Gdansk
24813742 98 Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors.EBI Universit£ degli Studi
24713308 48 Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity.EBI Siedlce University of Natural Sciences and Humanities
24589511 60 Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties.EBI University of Cagliari
24689792 54 Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.EBI Griffith University
24650641 110 Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII.EBI Universit£ degli Studi 'Aldo Moro' di Bari
23664215 45 Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening.EBI East China University of Science and Technology
23647428 84 Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo.EBI Universit£ degli Studi di Firenze
23490152 15 Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition.EBI University of Florida
23429054 48 Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship.EBI East China University of Science and Technology
23352754 28 o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII.EBI Istanbul University
23290254 92 Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII.EBI Salman Bin Abdulaziz University
23206986 259 QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII.EBI Romanian Academy
23199483 25 Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
23168081 72 New selective carbonic anhydrase IX inhibitors: synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides.EBI Univ. Lille Nord de France
23098607 2 Carbonic anhydrase IX as a target for metastatic disease.EBI University of Manchester
23018095 36 Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Pisa
23010455 108 Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.EBI Universidad Nacional de La Plata
22974493 13 Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity.EBI Agri Ibrahim Cecen University
22892213 168 Natural product coumarins that inhibit human carbonic anhydrases.EBI Griffith University
22705188 73 Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: new selective tumor-associated carbonic anhydrase inhibitors.EBI Superacide et Chimie des syst£mes£ team-Universit£ de Poitiers
22668600 200 Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV.EBI Universit£ degli Studi di Firenze
23265898 20 Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.EBI Universit£ degli Studi di Firenze
23241068 84 Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases.EBI Latvian Association of Human Genetics
23067387 105 Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.EBI Universit£ di Pisa
22894736 99 Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment.EBI The Hebrew University of Jerusalem
22775345 74 Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.EBI Istituto di Biostrutture e Bioimmagini-CNR
22621623 44 Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts.EBI University of Manchester
22901388 76 Inhibition ofa-class cytosolic human carbonic anhydrases I, II, IX and XII, andß-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors.EBI Universit£ di Sassari
22721713 200 Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
22443141 115 Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors.EBI Universit£ di Messina
22276570 112 Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.EBI Universit£ degli Studi di Firenze
22487176 109 Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.EBI Universit£ degli Studi di Cagliari
21211980 47 Characterization and anions inhibition studies of ana-carbonic anhydrase from the teleost fish Dicentrarchus labrax.EBI Ondokuz Mayis University
20580561 33 Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity.EBI Instituto Superior T£cnico
20674354 79 Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.EBI Universit£ degli Studi di Firenze
20605094 91 Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.EBI University of Florida
20598552 24 Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.EBI University of Florida
20478708 28 New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors.EBI LNEG
20472429 80 Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.EBI Istituto di Biostrutture e Bioimmagini-CNR
20201556 174 Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases.EBI Griffith University
20185318 132 Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.EBI Universit£ degli Studi di Firenze
19911821 273 Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.EBI Universita degli Studi di Firenze
20028100 78 The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Firenze
19827837 52 S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.EBI Griffith University
19398204 44 Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides.EBI Universit£ di Messina
19286378 75 Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties.EBI Griffith University
19186056 60 A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.EBI Universit£ degli Studi di Firenze
18513964 45 Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes.EBI Universit£ degli Studi di Firenze
18359629 84 Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.EBI Istituto di Biostrutture e Bioimmagini-CNR
18042384 60 Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
18307288 70 Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.EBI Griffith University
17475500 130 Carbonic anhydrases as targets for medicinal chemistry.EBI Universit£ degli Studi di Firenze
17681760 21 Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.EBI Griffith University
17376683 63 Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
17314045 11 Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.EBI Universit£ degli Studi di Firenze
17276072 95 Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates.EBI Universit£ di Pisa
17228881 141 Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.EBI Kochi Medical School
16290146 30 Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II"selective" inhibitor celecoxib.EBI Istituto di Biostrutture e Bioimmagini-CNR
16203142 55 Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.EBI Universit£ degli Studi di Firenze
16220969 219 Designed multiple ligands. An emerging drug discovery paradigm.EBI Organon Laboratories
15664816 65 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.EBI Universit£ degli Studi di Firenze
15664814 55 Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.EBI Universit£ degli Studi di Firenze
15603956 63 Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.EBI Harran University
16039848 93 Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.EBI Kochi Medical School
15905091 134 Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.EBI Universit£ degli Studi di Firenze
15546717 130 Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.EBI Pennsylvania State University
15501039 51 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.EBI Universit£ degli Studi di Firenze
15501038 68 Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.EBI Universit£ degli Studi di Firenze
15454239 74 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.EBI Universit£ degli Studi di Firenze
12747791 91 Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors.EBI Universit£ Montpellier II
15012984 192 Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.EBI Slovak Academy of Sciences
15081039 68 Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.EBI Universit£ degli Studi di Firenze
15203157 68 Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.EBI University of Tampere
15149691 32 Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.EBI Laxmi Fumigation and Pest Control (P)
14684333 9 Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase.EBI Universit£ degli Studi di Firenze
14684331 24 Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.EBI Universit£ degli Studi di Firenze
12643899 127 Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.EBI Universit£ degli Studi di Firenze
22377674 80 Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII.EBI Universit£ degli Studi di Firenze
22370338 183 Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases.EBI Griffith University
22365761 144 New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.EBI Universit£ degli Studi di Firenze
22077347 44 Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
22137345 36 5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Firenze
22041171 44 Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors.EBI Universit£ di Messina
21852133 68 Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.EBI University of Alberta
21851094 92 Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.EBI Griffith University
21821413 65 Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
21820216 75 Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives.EBI Medical University of Gdansk
21515057 153 Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.EBI Universit£ degli Studi di Firenze
21723123 48 N-ß-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.EBI Universidad Nacional de La Plata
21470859 52 Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
21549597 71 Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.EBI U.O. Oculistica Az. USL 3
21361354 112 Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.EBI Universita` degli Studi di Firenze
21314129 76 Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors.EBI Griffith University
21282059 48 Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site.EBI University of Calgary
21067924 88 7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range.EBI Università degli Studi di Firenze
20880712 69 Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors.EBI Univ Lille Nord de France
20554082 76 Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.EBI Medical University of Gdansk
20590092 273 Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.EBI Universita degli Studi di Firenze
20202722 138 Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides.EBI Medical University of Gdansk
19751975 6 The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors.EBI Universita degli Studi di Firenze
19615903 6 In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives.EBI Institute of Pharmaceutical Sciences
19527930 53 The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.EBI University of Tampere and Tampere University Hospital
19097911 41 Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors.EBI University of Namur
19053764 101 Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates.EBI Instituto Superior Técnico
18348513 19 Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs.EBI University of Namur
18295485 75 Carbonic anhydrase inhibitors: the very weak inhibitors dithiothreitol, beta-mercaptoethanol, tris(carboxyethyl)phosphine and threitol interfere with the binding of sulfonamides to isozymes II and IX.EBI Universita degli Studi di Firenze
17822907 90 Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity.EBI Assiut University
17257840 20 Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions.EBI Università degli Studi di Firenze
16809036 100 Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.EBI Medical University of Gdansk
16759856 9 N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors.EBI Università degli Studi di Firenze
16168653 100 Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.EBI Università degli Studi di Firenze
16165351 45 Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides.EBI Università degli Studi di Firenze
16033263 51 Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.EBI Università degli Studi di Firenze
15908204 116 Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.EBI Ospedale San Lazzaro
15908201 51 Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxic tumors.EBI Università degli Studi di Firenze
15837325 69 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.EBI Ospedale San Lazzaro
15837323 66 Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.EBI University of Bucharest
15780637 3 Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.EBI University of Naples 'Federico II'
15780631 55 Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with complex fluorides, chlorides and cyanides.EBI Università degli Studi di Firenze
15745821 21 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates.EBI Université Montpellier II
15664815 45 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates.EBI Università degli Studi di Firenze
15501037 27 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet.EBI Università degli Studi di Milano
14640555 96 Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.EBI Université Montpellier II
23914927 24 Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies.BDB University of Calgary
23488741 20 Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX.BDB S.G.S.I.T.S
23463940 4 Synthesis and evaluation of 18F-labeled carbonic anhydrase IX inhibitors for imaging with positron emission tomography.BDB BC Cancer Agency
22299576 44 Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors.BDB Ecole Nationale Supérieure de Chimie de Montpellier
22168802 12 Carbonic anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry.BDB Laboratoire Synthèse et Réactivité des Substances Naturelles
19170619 14 Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties.BDB University of Florida
18608752 48 Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.BDB Egyptian Petroleum Research Institute
15499999 35 Benzolamide is not a membrane-impermeant carbonic anhydrase inhibitor.BDB Università degli Studi di Firenze
19703035 60 Which carbonic anhydrases are targeted by the antiepileptic sulfonamides and sulfamates?BDB Istituto di Biostrutture e Bioimmagini-CNR
19731956 72 Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors.BDB CNR
19773173 60 Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II.BDB Universita degli Studi di Firenze
19193158 77 Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.BDB University of Tampere
19119014 12 Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference.BDB Universita degli Studi di Firenze
18579385 132 Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid.BDB Universita degli Studi di Firenze
18819811 195 Carbonic anhydrase inhibitors: synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides.BDB Istanbul University
18374572 100 Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.BDB Universita degli Studi di Firenze
18640037 48 Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD 486019 with twelve mammalian carbonic anhydrase isoforms: Kinetic and X-ray crystallographic studies.BDB Universita degli Studi di Firenze
17343373 54 Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.BDB Griffith University
15084132 88 Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.BDB Canadian Institutes of Health Research
14736236 20 Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.BDB University of Marburg
17125255 77 Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.BDB Universite Montpellier II
17064072 90 A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".BDB Griffith University
15771455 110 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating hydrazino moieties.BDB Universita degli Studi di Firenze
24090419 36 A systematic quantitative approach to rational drug design and discovery of novel human carbonic anhydrase IX inhibitors.BDB Birla Institute of Technology
16134940 20 Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.BDB Istituto di Biostrutture e Bioimmagini-CNR
12747790 171 Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.BDB University of Agricultural Sciences and Veterinary Medicine
16942027 69 Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX.BDB Istituto di Biostrutture e Bioimmagini-CNR
16640335 39 Indanesulfonamides as carbonic anhydrase inhibitors. Toward structure-based design of selective inhibitors of the tumor-associated isozyme CA IX.BDB University of Namur