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135 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
25522204 178 Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.EBI University of Minnesota
25638501 32 Scaffold hopping: exploration of acetanilide-containing uracil analogues as potential NNRTIs.EBI Volgograd State Medical University
15916427 55 Comparison of ligand-based and structure-based 3D-QSAR approaches: a case study on (aryl-)bridged 2-aminobenzonitriles inhibiting HIV-1 reverse transcriptase.EBI University of Perugia
8831772 18 Principal components describing biological activities and molecular diversity of heterocyclic aromatic ring fragments.EBI Organon Research Laboratories
16621553 52 Synthesis and biological investigation of S-aryl-S-DABO derivatives as HIV-1 inhibitors.EBI Universit£ degli Studi di Siena
14761194 15 Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.EBI Universit£ degli Studi di Roma"La Sapienza"
12190315 43 Synthesis of 3' '-substituted TSAO derivatives with anti-HIV-1 and anti-HIV-2 activity through an efficient palladium-catalyzed cross-coupling approach.EBI Instituto de Qu£mica M£dica (C.S.I.C.)
10821705 27 Synthesis and evaluation of"AZT-HEPT","AZT-pyridinone", and"ddC-HEPT" conjugates as inhibitors of HIV reverse transcriptase.EBI UMR 176 CNRS/Institut Curie
9685236 132 Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 8. 8-Aryloxymethyl- and 8-arylthiomethyldipyridodiazepinones.EBI Boehringer Ingelheim Pharmaceuticals Inc.
7996541 12 Synthesis, in vitro biological stability, and anti-HIV activity of 5-halo-6-alkoxy(or azido)-5,6-dihydro-3'-azido-3'-deoxythymidine diastereomers as potential prodrugs to 3'-azido-3'-deoxythymidine (AZT).EBI University of Alberta
7683054 115 Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogues.EBI Merck Reserch Laboratories
15149669 38 5-Alkyl-2-[(aryl and alkyloxylcarbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones as an unique HIV reverse transcriptase inhibitors of S-DABO series.EBI Fudan University
16632349 2 Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1.EBI Genomics Institute of the Novartis Research Foundation
16527484 31 New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: synthesis, resolution, and inhibitory activity.EBI NIH
15801860 22 Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.EBI Biota, Inc.
15974590 5 Novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. A structure-activity relationship investigation.EBI Universit£ di Roma La Sapienza
15916438 17 Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.EBI Universit£ di Genova
15686877 2 4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase.EBI Universit£t Konstanz
15341930 8 Inhibition of the strand transfer step of HIV-1 integrase by non-natural dinucleotides.EBI University of Georgia
14971897 3 Novel benzophenones as non-nucleoside reverse transcriptase inhibitors of HIV-1.EBI GlaxoSmithKline Inc.
14561099 9 Inhibition of human immunodeficiency virus reverse transcriptase by synadenol triphosphate and its E-isomer.EBI Wayne State University School of Medicine
14521410 36 Identification and prediction of promiscuous aggregating inhibitors among known drugs.EBI Northwestern University
12852759 2 A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.EBI National Cancer Institute-Frederick
12723951 7 Antiviral amphipathic oligo- and polyribonucleotides: analogue development and biological studies.EBI University of Utah
11462972 93 Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.EBI Universita' degli Studi di Salerno
11087576 33 Syntheses of 4'-C-ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosylpyrimidines and -purines and evaluation of their anti-HIV activity.EBI Tohoku University
10882373 15 6-N-Acyltriciribine analogues: structure-activity relationship between acyl carbon chain length and activity against HIV-1.EBI University of Michigan
10882371 8 Deoxy sugar analogues of triciribine: correlation of antiviral and antiproliferative activity with intracellular phosphorylation.EBI University of Michigan
10072684 8 Prediction of the binding free energies of new TIBO-like HIV-1 reverse transcriptase inhibitors using a combination of PROFEC, PB/SA, CMC/MD, and free energy calculations.EBI University of California at San Francisco
10072683 4 Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.EBI Emory University
9857095 12 Prediction of binding affinities for TIBO inhibitors of HIV-1 reverse transcriptase using Monte Carlo simulations in a linear response method.EBI Western Maryland College
9622545 41 Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase.EBI Max-Delbr�ck-Centrum f�r Molekulare Medizin
8667357 33 Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.EBI IBM Thomas J. Watson Research Center
7525960 2 The synthesis of nucleoside 5'-O-(1,1-dithiotriphosphates).EBI Polish Academy of Sciences
8385224 9 Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs.EBI URA CNRS 1309
7506311 18 The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn.EBI SmithKline Beecham Pharmaceuticals R& D
1282569 108 Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities.EBI Universityof Illinois at Chicago
1527788 2 3',3'-Difluoro-3'-deoxythymidine: comparison of anti-HIV activity to 3'-fluoro-3'-deoxythymidine.EBI Purdue University
1375962 9 New thymidine triphosphate analogue inhibitors of human immunodeficiency virus-1 reverse transcriptase.EBI University of California
1697345 3 5'-O-phosphonomethyl-2',3'-dideoxynucleosides: synthesis and anti-HIV activity.EBI Institute for Medical Research
14643337 38 Synthesis of non-immunosuppressive cyclophilin-Binding cyclosporin A derivatives as potential anti-HIV-1 drugs.EBI Centre de Recherche de Paris
12781181 8 The role of 2',3'-unsaturation on the antiviral activity of anti-HIV nucleosides against 3TC-resistant mutant (M184V).EBI The University of Georgia
11266155 7 Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor efavirenz.EBI DuPont Pharmaceuticals Company
11212098 25 Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase.EBI DuPont Pharmaceuticals Company
11597403 17 Antiviral drug design: computational analyses of the effects of the L100I mutation for HIV-RT on the binding of NNRTIs.EBI Yale University
11591519 20 Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase.EBI University of Toledo
11206461 10 3,3a-Dihydropyrano[4,3,2-de]quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors.EBI DuPont Pharmaceuticals Company
10673109 9 Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors.EBI DuPont Pharmaceuticals Company
10999473 26 Stereochemistry of halopyridyl and thiazolyl thiourea compounds is a major determinant of their potency as nonnucleoside inhibitors of HIV-1 reverse transcriptase.EBI Institute
10386942 14 Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus.EBI Institute
 1 Novel oligodeoxyribonucleotides incorporating L-related isodeoxynucleosides: Solid phase synthesis, enzymology, and CD studiesEBI TBA
 3 Synthesis and HIV-1 reverse transcriptase inhibition properties of two new methylenephosphonate analogues of 3-azido-3-deoxythymidine-5-triphosphateEBI TBA
 4 Synthesis of a difluoromethylenephosphonate analogue of AZT 5'-triphosphate and its inhibition of HIV-1 reverse transcriptaseEBI TBA
 11 1-Arylsulfonyl-3-(α-hydroxybenzyl)-1H-pyrroles, a novel class of anti-HIV-1 reverse transcriptase inhibitorsEBI TBA
 8 Lipophilic bioisosteres of nucleoside triphosphatesEBI TBA
 11 Isosteres of nucleoside triphosphatesEBI TBA
 29 2-Heterocyclic indole-3-sulfones as inhibitors of HIV-1 reverse transcriptaseEBI TBA
 1 Synthesis and biological evaluation of an alkenyldiarylmethane (ADAM) which acts as a novel non-nucleoside HIV-1 reverse transcriptase inhibitorEBI TBA
 6 The synthesis of a dipyrido[3,2-b:3′,4′-e][1,4]diazepinone: Convenient access to a C-ring isomer of the HIV-1 reverse transcriptase inhibitor nevirapineEBI TBA
 1 2′-Deoxyadenylyl-(3′→5′)-isodideoxyadenosine, a unique dinucleotide: Synthesis, enzymology, and conformational studiesEBI TBA
 2 Design and synthesis of a conformationally constrained analog of the bis(heteroaryl)piperazine (BHAP) HIV-1 reverse transcriptase inhibitor atevirdineEBI TBA
 5 Aromatic amino acid phosphoramidate di- and triesters of 3′-azido-3′-deoxythymidine (AZT) are non-toxic inhibitors of HIV-1 replicationEBI TBA
 47 Imidazo[2′-3′-:6,5]dipyrido[3,2-b:2′,3′-e]-1,4-diazepines: non-nucleoside HIV-1 reverse transcriptase inhibitors with greater enzyme affinity than nevirapineEBI TBA
16913724 17 Design and discovery of a novel dipeptidyl-peptidase IV (CD26)-based prodrug approach.EBI Instituto de Química Médica (C.S.I.C.)
16913721 11 Replacement of the metabolically labile methyl esters in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors with isoxazolone, isoxazole, oxazolone, or cyano substituents.EBI Purdue University
16884295 48 Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization.EBI University of Pittsburgh School of Medicine
16854079 57 Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109.EBI Central Pharmaceutical Research Institute
16722622 24 Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.EBI Wyeth Research
16503141 29 Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant.EBI MRL Rome
16274990 21 Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase.EBI Wyeth Research
16220981 28 Improving the antiviral efficacy and selectivity of HIV-1 reverse transcriptase inhibitor TSAO-T by the introduction of functional groups at the N-3 position.EBI Instituto de Química Médica (C.S.I.C.)
16162014 20 Synthesis, anti-HIV activity, and metabolic stability of new alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors.EBI Purdue University
16137881 9 4-Phenylcoumarins as HIV transcription inhibitors.EBI Instituto de Salud Carlos III
16107158 60 Novel 8-substituted dipyridodiazepinone inhibitors with a broad-spectrum of activity against HIV-1 strains resistant to non-nucleoside reverse transcriptase inhibitors.EBI Boehringer Ingelheim (Canada) Ltd.
16002283 12 New HIV-1 replication inhibitors of the styryquinoline class bearing aroyl/acyl groups at the C-7 position: synthesis and biological activity.EBI Unité Associée au CNRS
15916436 2 Design, synthesis and antiviral activity of novel 4,5-disubstituted 7-(beta-D-ribofuranosyl)pyrrolo[2,3-d][1,2,3]triazines and the novel 3-amino-5-methyl-1-(beta-D-ribofuranosyl)- and 3-amino-5-methyl-1-(2-deoxy-beta-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,7,8-hexaazaacenaphthylene as analogues of triEBI University of Michigan
15686922 16 Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives.EBI Kyoritsu University of Pharmacy
15634005 108 Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.EBI University of Southern California
15546736 16 QSAR modelling of HIV-1 reverse transcriptase inhibition by benzoxazinones using a combination of P_VSA and pharmacophore feature descriptors.EBI S.G.S.I.T.S.
15481994 1 Spectroscopic studies of diketoacids-metal interactions. A probing tool for the pharmacophoric intermetallic distance in the HIV-1 integrase active site.EBI Université des Sciences et Technologies de Lille
15481971 32 HCV NS5b RNA-dependent RNA polymerase inhibitors: from alpha,gamma-diketoacids to 4,5-dihydroxypyrimidine- or 3-methyl-5-hydroxypyrimidinonecarboxylic acids. Design and synthesis.EBI Italy. Vinc
15189038 16 Hybrids of [TSAO-T]-[foscarnet]: The first conjugate of foscarnet with a non-nucleoside reverse transcriptase inhibitor through a labile covalent ester bond.EBI Instituto de Química Médica (C.S.I.C.)
14698176 5 Effects of fluorine substitution of cytosine analogues on the binding affinity to HIV-1 reverse transcriptase.EBI The University of Georgia
14695815 33 Discovery of alpha,gamma-diketo acids as potent selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase.EBI Italy. Vinc
14667230 7 Novel lavendamycin analogues as potent HIV-reverse transcriptase inhibitors: synthesis and evaluation of anti-reverse transcriptase activity of amide and ester analogues of lavendamycin.EBI Ball State University
12723956 22 Molecular modeling calculations of HIV-1 reverse transcriptase nonnucleoside inhibitors: correlation of binding energy with biological activity for novel 2-aryl-substituted benzimidazole analogues.EBI National Cancer Institute-Frederick
12593657 66 Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives.EBI Università di Genova
12477350 47 Metal-dependent inhibition of HIV-1 integrase.EBI University of Southern California
12431069 11 Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents.EBI Università di Messina
11881997 14 Carbocyclic dinucleoside polyphosphonates: interaction with HIV reverse transcriptase and antiviral activity.EBI Russian Academy of Sciences
11844664 35 Differential inhibition of polymerase and strand-transfer activities of HIV-1 reverse transcriptase.EBI University of Toledo
11714616 28 Identification of a novel family of nucleosides that specifically inhibit HIV-1 reverse transcriptase.EBI Instituto de Química Médica (C.S.I.C.)
11229762 25 Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds.EBI Institute
11170624 40 Estimation of binding affinities for HEPT and nevirapine analogues with HIV-1 reverse transcriptase via Monte Carlo simulations.EBI Yale University
10636251 14 Antioxidant function of phenethyl-5-bromo-pyridyl thiourea compounds with potent anti-HIV activity.EBI Institute
10617082 15 N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.EBI Institute
10543890 61 Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity.EBI Universita' degli Studi di Salerno
10514284 41 Synthesis and structure-activity relationships of the (alkylamino)piperidine-containing BHAP class of non-nucleoside reverse transcriptase inhibitors: effect of 3-alkylpyridine ring substitution.EBI Pharmacia & Upjohn
10509923 9 N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.EBI Institute
10098659 1 Synthesis of 5,8-dimethoxy-3-hydroxy-4-quinolone, a reported inhibitor of HIV RT, and evidence the original proposed structure was incorrect.EBI MediChem Research, Inc.
9873592 44 Biaryl acids: novel non-nucleoside inhibitors of HIV reverse transcriptase types 1 and 2.EBI GlaxoWellcome Medicines Research Center
9873507 15 A dipyrido [2,3-b:3',2'-f]azepine analog of the HIV-1 reverse transcriptase inhibitor nevirapine.EBI Boehringer Ingelheim Pharmaceuticals
9873380 52 Synthesis and anti-HIV activities of urea-PETT analogs belonging to a new class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.EBI Medivir AB
9873370 5 5-Alkyl-2-[(methylthiomethyl)thio]-6-(benzyl)-pyrimidin-4-(1H)-ones as potent non-nucleoside reverse transcriptase inhibitors of S-DABO series.EBI Institute
9871737 5 Design and synthesis of bio-isosteres of thymidine triphosphate.EBI University of Wales Cardiff
9871653 1 Synthesis of a non-nucleoside reverse transcriptase inhibitor in the alkenyldiarylmethane (ADAM) series with optimized potency and therapeutic index.EBI Purdue University
9748354 30 Pyrimidine thioethers: a novel class of HIV-1 reverse transcriptase inhibitors with activity against BHAP-resistant HIV.EBI Pharmacia & Upjohn
9719591 22 New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development.EBI Ciba-Geigy AG
9554867 18 (-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.EBI Pharmacia & Upjohn
9548815 10 Design, synthesis, and antiviral evaluations of 1-(substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles as nonnucleoside analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole.EBI University of Michigan
9438017 12 (Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.EBI Wayne State University School of Medicine
9435895 90 A 3D QSAR study of a series of HEPT analogues: the influence of conformational mobility on HIV-1 reverse transcriptase inhibition.EBI Université d'Orléans
9435891 62 Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles.EBI National Cancer Institute-Frederick Cancer Research and Development Center
9240351 4 Synthesis and anti-HIV-1 activity of a series of 1-alkoxy-5-alkyl-6-(arylthio)uracils.EBI Life Science Research Center
9216838 1 Phosphodiester amidates of unsaturated nucleoside analogues: synthesis and anti-HIV activity.EBI Wayne State University School of Medicine
9154976 18 Preparation and anti-HIV activity of N-3-substituted thymidine nucleoside analogs.EBI Institut de Chimie des Substances Naturelles CNRS
9083491 8 Structural analogues of the calanolide anti-HIV agents. Modification of the trans-10,11-dimethyldihydropyran-12-ol ring (ring C).EBI MediChem Research, Inc.
8978855 16 Synthesis and bioactivity of novel bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships and increased metabolic stability of novel substituted pyridine analogs.EBI Pharmacia & Upjohn
8709096 26 Pyrrolobenzothiazepinones and pyrrolobenzoxazepinones: novel and specific non-nucleoside HIV-1 reverse transcriptase inhibitors with antiviral activity.EBI Universitá di Siena
8648604 15 All-atom models for the non-nucleoside binding site of HIV-1 reverse transcriptase complexed with inhibitors: a 3D QSAR approach.EBI National Cancer Institute-FCRDC
8648598 3 Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.EBI Oxford
7837220 5 Anti-human immunodeficiency virus and anti-hepatitis-B virus activities and toxicities of the enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine and their 5-fluoro analogues in vitro.EBI BioChem Therapeutic Inc.
7681480 7 Non-nucleoside inhibitors of HIV-1 reverse transcriptase: molecular modeling and X-ray structure investigations.EBI Boehringer Mannheim GmbH
7562946 7 Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin.EBI University of Michigan
7540209 11 Design and synthesis of novel inhibitors of HIV-1 reverse transcriptase.EBI State University of New York
7537334 18 Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 3. Dipyrido[2,3-b:2',3'-e]diazepinones.EBI Boehringer Ingelheim Pharmaceuticals
7520080 18 Synthesis of naphthalenesulfonic acid small molecules as selective inhibitors of the DNA polymerase and ribonuclease H activities of HIV-1 reverse transcriptase.EBI College of Pharmacy
7473595 12 A new series of pyridinone derivatives as potent non-nucleoside human immunodeficiency virus type 1 specific reverse transcriptase inhibitors.EBI URA 1387 CNRS
2479745 5 A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.EBI Showa University
1720175 7 Activity of acyclic 6-(phenylselenenyl)pyrimidine nucleosides against human immunodeficiency viruses in primary lymphocytes.EBI Veterans Affairs Medical Center
17184135 28 HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site.BDB Rutgers University
19791799 18 RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.BDB Gilead Sciences Inc.