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6 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27818110 61 Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology.EBI Merck Research Laboratories
26087021 94 Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate.EBI TBA
23964859 48 Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia.EBI Novartis Institutes for BioMedical Research
21831639 32 Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders.EBI GlaxoSmithKline Medicine Research Centre