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12 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27994738 50 Sulfonamides as Selective NaEBI Amgen, Inc.
26985315 49 Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models.EBI Xenon Pharmaceuticals, Inc.
26358159 114 Discovery of (phenoxy-2-hydroxypropyl)piperidines as a novel class of voltage-gated sodium channel 1.7 inhibitors.EBI Daiichi Sankyo Co., Ltd
25927480 36 Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications.EBI Merck Research Laboratories
25658507 218 Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.EBI Amgen Inc.
22770500 219 3-Oxoisoindoline-1-carboxamides: potent, state-dependent blockers of voltage-gated sodium channel Na(V)1.7 with efficacy in rat pain models.EBI AstraZeneca
22939696 85 Phenethyl nicotinamides, a novel class of Na(V)1.7 channel blockers: structure and activity relationship.EBI AstraZeneca
21962108 14 Lactam-stabilized helical analogues of the analgesicµ-conotoxin KIIIA.EBI Monash University
17724025 8 Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.EBI University of Utah