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24 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
24955889 16 Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis.EBI Institute of Chinese Materia Medica
9836620 94 N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents.EBI Glaxo Wellcome Research and Development
24462665 30 Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPAR┐ agonists.EBI GlaxoSmithKline R&D
20527969 27 Design, synthesis, and structure-activity relationship studies of novel 2,4,6-trisubstituted-5-pyrimidinecarboxylic acids as peroxisome proliferator-activated receptor gamma (PPARgamma) partial agonists with comparable antidiabetic efficacy to rosiglitazone.EBI Kyorin Pharmaceutical Co., Ltd.
17964792 31 Structure-activity studies on 1,3-dioxane-2-carboxylic acid derivatives, a novel class of subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists.EBI Nippon Shinyaku Co., Ltd
18280733 27 Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists.EBI Nippon Shinyaku Co., Ltd
22133631 76 Discovery of cyclic amine-substituted benzoic acids as PPARa agonists.EBI Kyorin Pharmaceutical Co., Ltd
21493073 1 Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.EBI Kyoto Pharmaceutical University
20452212 26 Glycine amides as PPARalpha agonists.EBI Bayer-Schering Pharma
20079636 78 Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators.EBI Centre de Recherches
18947994 102 The discovery of equipotent PPARalpha/gamma dual activators.EBI Centre de Recherches
18752947 7 New PPARgamma ligands based on barbituric acid: virtual screening, synthesis and receptor binding studies.EBI National Institute of Pharmaceutical Education and Research
18482837 5 New PPARgamma ligands based on 2-hydroxy-1,4-naphthoquinone: computer-aided design, synthesis, and receptor-binding studies.EBI National Institute of Pharmaceutical Education and Research
18060776 100 Design, synthesis and evaluation of trifluoromethane sulfonamide derivatives as new potent and selective peroxisome proliferator-activated receptor alpha agonists.EBI Centre de Recherches
17157013 74 Indanylacetic acid derivatives carrying aryl-pyridyl and aryl-pyrimidinyl tail groups--new classes of PPAR gamma/delta and PPAR alpha/gamma/delta agonists.EBI Bayer Pharmaceuticals Corporation
15293980 47 Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes.EBI GlaxoSmithKline
15163205 94 (2R)-2-ethylchromane-2-carboxylic acids: discovery of novel PPARalpha/gamma dual agonists as antihyperglycemic and hypolipidemic agents.EBI Merck Research Laboratories
12954061 153 Design, synthesis, and structure-activity relationship studies of novel 6,7-locked-[7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta]-2,4,6-trienoic acids.EBI Ligand Pharmaceuticals, Inc.
12699745 49 Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity.EBI GlaxoSmithKline
11677135 21 Identification of a series of PPAR gamma/delta dual agonists via solid-phase parallel synthesis.EBI GlaxoSmithKline
11354382 42 Identification of a subtype selective human PPARalpha agonist through parallel-array synthesis.EBI GlaxoSmithKline
10691680 72 The PPARs: from orphan receptors to drug discovery.EBI Glaxo Wellcome Research & Development
10508427 42 A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity.EBI Glaxo Wellcome Research & Development
8576907 13 The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones.EBI Glaxo Wellcome Research and Development