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43 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27100031 85 A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases.EBI Wroclaw University of Technology
26629857 44 Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.EBI Fudan University
26463133 22 Influence of polar side chains modifications on the dual enkephalinase inhibitory activity and conformation of human opiorphin, a pain perception related peptide.EBI Institute of Advanced Chemistry of Catalonia (IQAC-CSIC)
26241877 7 Modulation of disulfide dual ENKephalinase inhibitors (DENKIs) activity by a transient N-protection for pain alleviation by oral route.EBI Pharmaleads
25982416 43 Exploring S1 plasticity and probing S1' subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors.EBI Universit£ de Haute Alsace
25192493 57 Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.EBI University of Athens
24927250 18 New orally active dual enkephalinase inhibitors (DENKIs) for central and peripheral pain treatment.EBI Pharmaleads , Paris BioPark, 11 Rue Watt, 75013 Paris, France.
23860593 17 Novel▀-dicarbonyl derivatives as inhibitors of aminopeptidase N (APN).EBI Shandong University
23664876 1 Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor.EBI The University of Oklahoma Health Sciences Center
23528299 4 Discovery of a synthetic Aminopeptidase N inhibitor LB-4b as a potential anticancer agent.EBI Shandong University
23510562 30 Novel indoline-2,3-dione derivatives as inhibitors of aminopeptidase N (APN).EBI Shandong University
23428964 9 Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy.EBI Universit£ de Haute-Alsace
23453219 29 Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN).EBI Shandong University
19757839 26 The replacement of His(4) in angiotensin IV by conformationally constrained residues provides highly potent and selective analogues.EBI Vrije Universiteit Brussel
22796349 34 Rapid and efficient synthesis of a novel series of substituted aminobenzosuberone derivatives as potent, selective, non-peptidic neutral aminopeptidase inhibitors.EBI Universit£ de Haute Alsace
21780776 40 Remarkable potential of thea-aminophosphonate/phosphinate structural motif in medicinal chemistry.EBI Wroclaw University of Technology
22607877 38 Design, synthesis and biological evaluation of novel amino acid ureido derivatives as aminopeptidase N/CD13 inhibitors.EBI Shandong University
22224710 44 Structure-activity relationship study of opiorphin, a human dual ectopeptidase inhibitor with antinociceptive properties.EBI Institute of Advanced Chemistry of Catalonia (IQAC-CSIC)
19822427 21 Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity.EBI Loyola University
17331715 19 Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors.EBI Korea Research Institute of Chemical Technology
15582436 7 N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity.EBI Sejong University
11585456 8 Long lasting antinociceptive properties of enkephalin degrading enzyme (NEP and APN) inhibitor prodrugs.EBI INSERM
7909847 33 Investigation of the active site of aminopeptidase A using a series of new thiol-containing inhibitors.EBI INSERM
12873488 11 Design, synthesis and antimalarial activity of novel, quinoline-based, zinc metallo-aminopeptidase inhibitors.EBI Universit£ de Lille 2
10098663 37 Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs.EBI University of Tokyo
 40 Pseudopeptide inhibitors of aminopeptidases containing the [CH(CN)NH] surrogate as a transition-state MIMICEBI TBA
21911297 40 Design, synthesis and biological evaluation of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as aminopeptidase N/CD13 inhibitors.EBI Shan Dong University
21802307 64 Novel aminopeptidase N (APN/CD13) inhibitors derived from chloramphenicol amine.EBI Shandong University
21476495 31 Potent macrocyclic inhibitors of insulin-regulated aminopeptidase (IRAP) by olefin ring-closing metathesis.EBI Uppsala University
21306895 46 Discovery ofß-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors.EBI Korea Research Institute of Chemical Technology
21292493 23 Amino-benzosuberone: a novel warhead for selective inhibition of human aminopeptidase-N/CD13.EBI Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France.
21047126 51 Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP).EBI Uppsala University
20129718 32 Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Structure-based design, chemistry and activity evaluation. II.EBI Shandong University
20347318 49 New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.EBI Wroclaw University of Technology
18718763 50 Synthesis of new sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.EBI Shandong University
18556208 48 Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2.EBI Uppsala University
18440232 38 Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.EBI Shandong University
18362041 59 Design, synthesis and preliminary evaluation of novel pyrrolidine derivatives as matrix metalloproteinase inhibitors.EBI Shandong University
17270439 23 Novel hydroxamic acid-related phosphinates: inhibition of neutral aminopeptidase N (APN).EBI Wroclaw University of Technology
10090787 25 Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors.EBI University of Antwerp (UIA)
1738140 26 alpha-Keto amide inhibitors of aminopeptidases.EBI University of Wisconsin-Madison