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Compounds Sorted by Binding Targets per Compound

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Compounds Sorted Alphabetically

Compound Name (alphabetical)	Binding Targets	Enz. Inhib. Data							ITC Data	Alternate Compound Names
		Ki	IC50	Kd	EC50	Koff	Kon	Other
BDBM10859	β-Carbonic anhydrase 2 (CA 2) Alpha carbonic anhydrase Astrosclerin-3 Beta-carbonic anhydrase Carbonate dehydratase Carbonic Anhydrase (hpCA) Carbonic Anhydrase (mtCA 1) Carbonic Anhydrase (mtCA 3) Carbonic Anhydrase 2 (Can2) Carbonic Anhydrase III Carbonic Anhydrase VA Carbonic Anhydrase VB Carbonic Anhydrase XV Carbonic anhydrase Carbonic anhydrase 1 Carbonic anhydrase 12 Carbonic anhydrase 2 Carbonic anhydrase 6 (CA-VI) Carbonic anhydrase 7 Carbonic anhydrase 9 Carbonic anhydrase, alpha family Carbonic anhydrases; II & IX Delta carbonic anhydrase beta-Carbonic Anhydrase	83	5	6	0	0	0	0	0	4-methylbenzene-1-sulfonamide CHEMBL574 aromatic/heteroaromatic sulfonamide 4 hCA inhibitor, 7
BDBM18207	Androgen Receptor Androgen receptor Arachidonate 5-lipoxygenase Bile salt export pump Bile salt export pump (BSEP) Cyclooxygenase Cyclooxygenase-1 (COX-1) Cytochrome P450 2J2 Cytochrome P450 3A Glucocorticoid Glucocorticoid receptor Liver fatty acid binding protein (rat L-FABP) Mineralocorticoid receptor Multidrug and toxin extrusion protein 1 Nuclear receptor subfamily 1 group I member 2 P-glycoprotein (P-gp) P-glycoprotein 1 P-glycoprotein 1 and 3 (MDR1a/MDR1b) Phospholipase A2 Phospholipase A2 group 1B Phospholipase A2, major isoenzyme Progesterone receptor Prostaglandin G/H synthase (cyclooxygenase) Secretory phospholipase A2, group V (sPLA2-V)	24	86	1	37	0	0	0	0	(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one dexamethasone dexamethasone (tetramethyl-rhodamine conjugated )
BDBM18355	Acidic alpha-glucosidase Alpha glucosidase Alpha-glucosidase Alpha-mannosidase 2C1 Beta-galactosidase Beta-glucosidase Beta-mannosidase Ceramide glucosyltransferase Glucocerebrosidase GBA1/GBA2 Glucosylceramidase Glycogen debranching enzyme Lactase-glycosylceramidase Lactase-phlorizin hydrolase Lysosomal alpha-glucosidase Maltase-glucoamylase Mannosidase 2 alpha 1 Mannosidase 2, alpha B1 Non-lysosomal glucosylceramidase Sucrase-isomaltase Trehalase Uncharacterized protein alpha-Glucosidase (α-Glucosidase) alpha-Glucosidase (alpha-Glu) alpha-glucosidase (Gaa)	3	52	0	1	0	0	0	0	(2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol CHEMBL1029 MIGLUSTAT N-Butyl-DNJ US9181184, 5
BDBM23416	Aldose reductase Arginase Carbonic Anhydrase III Carbonic Anhydrase VA Carbonic Anhydrase VB Carbonic Anhydrase XIV Carbonic anhydrase 1 Carbonic anhydrase 12 Carbonic anhydrase 13 (CA XIII) Carbonic anhydrase 15 Carbonic anhydrase 2 Carbonic anhydrase 3 (CA III) Carbonic anhydrase 4 Carbonic anhydrase 6 (CA-VI) Carbonic anhydrase 7 Carbonic anhydrase 9 Cyclooxygenase Death-associated protein kinase 1 Lymphocyte differentiation antigen CD38 Prostaglandin G/H synthase (cyclooxygenase) Thrombin and coagulation factor X Xanthine dehydrogenase/oxidase alpha-Amylase alpha-Glucosidase (α-Glucosidase)	18	10	2	0	0	0	1	0	α-CA inhibitor, 3 (+)-Catechin (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol CHEMBL311498 Catechin D-Catechin
BDBM23620	Adrenergic Alpha Equilibrative Nucleoside Transporter 1 (ENT1) Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1) Heat shock protein HSP 90-alpha Multidrug and toxin extrusion protein 1 Multidrug and toxin extrusion protein 2 Multidrug resistance-associated protein 4 Multidrug resistance-associated protein 5 P-glycoprotein 1 Phosphodiesterase (TcrPDEC) Phosphodiesterase 1 Phosphodiesterase 11A (PDE11A) Phosphodiesterase 3 Phosphodiesterase 3A Phosphodiesterase 4 Phosphodiesterase 4A Phosphodiesterase 6 Phosphodiesterase 7 Phosphodiesterase 8 Protein prune homolog Solute carrier family 22 member 2 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-specific 3',5'-cyclic phosphodiesterase	8	28	0	0	0	0	0	0	2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol CHEMBL932 DIPYRIDAMOLE Dipyridamine Dipyridamole Dipyudamine MLS000028420 Persantine SMR000058382 cid_3108
BDBM24226	1,3-beta-glucan synthase component GLS2 Bile salt export pump Cytochrome P450 1A Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2D6 (2D6) Cytochrome P450 3A Glycine receptor subunit alpha-1 Heparanase Histamine H1 receptor Histamine H4 receptor Multidrug and toxin extrusion protein 1 P-glycoprotein (P-gp) P-glycoprotein 1 P-glycoprotein 1 and 3 (MDR1a/MDR1b) Polycomb protein EED (EED) Potassium voltage-gated channel subfamily H member 2 Protein Farnesyltransferase (PFT) Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5 ubiquitin-conjugating enzyme E2 N	15	30	2	1	0	0	0	0	1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine ASTEMIZOLE Astemizole, [O-Methyl-3H] CHEMBL296419 Hismanal Histaminos [3H]-ASTEMIZOLE [3H]Astemizole cid_2247
BDBM26187	Carbonic Anhydrase (mtCA 1) Carbonic Anhydrase 2 (Can2) Carbonic Anhydrase III Carbonic Anhydrase VA Carbonic Anhydrase VB Carbonic Anhydrase XIII Carbonic Anhydrase XIV Carbonic anhydrase Carbonic anhydrase 1 Carbonic anhydrase 12 Carbonic anhydrase 13 (CA XIII) Carbonic anhydrase 15 Carbonic anhydrase 2 Carbonic anhydrase 3 (CA III) Carbonic anhydrase 4 Carbonic anhydrase 6 (CA-VI) Carbonic anhydrase 7 Carbonic anhydrase 9 Estradiol receptor beta (ERβ) Estrogen receptor GABA receptor alpha-1/beta-2/gamma-2 subunit Lysozyme(L99A/M102Q) PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) beta-Carbonic Anhydrase	93	3	1	2	0	0	0	2	α-CA inhibitor, 11 CHEMBL14060 US9688816, 2 phenol
BDBM26197	5-lipoxygenase/FLAP Anandamide amidohydrolase Bile salt export pump Bile salt export pump (BSEP) Carbonic Anhydrase III Carbonic Anhydrase VA Carbonic Anhydrase VB Carbonic Anhydrase XIII Carbonic Anhydrase XIV Carbonic anhydrase 1 Carbonic anhydrase 12 Carbonic anhydrase 15 Carbonic anhydrase 2 Carbonic anhydrase 4 Carbonic anhydrase 6 (CA-VI) Carbonic anhydrase 7 Carbonic anhydrase 9 Cyclooxygenase Cyclooxygenase-1 (COX-1) Cytochrome P450 1A Cytochrome P450 1A1 Cytochrome P450 2J2 Myoglobin Solute carrier family 22 member 6	24	12	1	0	0	0	0	0	CHEMBL112 N-(4-hydroxyphenyl)acetamide Norco Paracetamol US9333197, Acetaminophen acetaminophen phenol derivative, 11
BDBM26664	12-Lipoxygenase (12-LOX) 15-Lipoxygenase-2 (15-LOX-2) 17-beta-hydroxysteroid dehydrogenase type 3 Acetylcholinesterase Adenosine Receptors A2a (A2a) Adenosine receptor A1 Aldose reductase (ALR2) Androgen receptor Arachidonate 15-lipoxygenase Aromatase (CYP19) Butyrylcholinesterase (BuChE) Calmodulin Carbonic anhydrase 1 Carbonic anhydrase 12 Carbonic anhydrase 2 Carbonic anhydrase 9 Cytochrome P450 1A Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) Estradiol 17-beta-dehydrogenase 2 Fatty acid synthase P-glycoprotein 1 Serine/threonine-protein kinase PIM Tyrosine-protein kinase Lck Xanthine dehydrogenase/oxidase	12	21	1	0	0	0	0	0	7-Hydroxy-flavone, 5a 7-Hydroxyflavone, 11 7-hydroxy-2-phenyl-4H-chromen-4-one 7-hydroxyflavone CHEMBL276915
BDBM34671	Apoptotic peptidase activating factor 1 Apurinic-apyrimidinic endonuclease 1 (APE-1) Caspase-9 DNA recombination protein RecA HSP90 and hnRNPA2/B1 Hematopoietic protein-tyrosine phosphatase (HEPTP) Lipoamide Dehydrogenase (Lpd) MPI protein MSRA protein Phospholipase A2 Pyruvate dehydrogenase (PDH) Serine/threonine-protein kinase PLK1 Sphingosine 1-Phosphate Receptor 2 Trypanosoma brucei RNA editing ligase 1 Tyrosine-protein kinase ABL1 Tyrosine-protein phosphatase non-receptor type 22 Valosin-containing protein cell division cycle 42 (GTP binding protein, 25kDa) cysteine protease ATG4B isoform a mothers against decapentaplegic homolog 3 nuclear receptor corepressor 2 isoform 2 photoreceptor-specific nuclear receptor streptokinase A precursor tyrosyl-DNA phosphodiesterase 2	0	23	2	7	0	0	0	0	1,3,6-Trimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-quinone MLS000528498 SMR000121073 US9073941, 611 cid_460747
BDBM35847	Bile salt export pump Organic anion-transporting polypeptide 1D1 (Oatp1d1) PTGDR PTGER3 PTGER4 PTGFR PTGIR Prostaglandin D Synthase Prostaglandin E2 receptor Prostaglandin E2 receptor EP1 subtype (EP1) Prostaglandin E2 receptor EP2 subtype Prostaglandin E2 receptor EP4 subtype Prostaglandin F2-alpha receptor Prostaglandin Transporter Prostanoid EP1 Receptor Prostanoid EP2 Receptor Prostanoid EP2 receptor Prostanoid EP3 Receptor Prostanoid EP4 Receptor Prostanoid EP4 receptor Prostanoid IP receptor Solute carrier family 22 member 20 Solute carrier family 22 member 6 TBXA2R	46	12	0	14	0	0	0	0	(15S)-prostaglandin E2 (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid CHEMBL548 DINOPROSTONE PGE2 [3H]Dinoprostone [3H]PGE2 [3H]Prostaglandin E2 prostaglandin E2
BDBM4810	ALK tyrosine kinase receptor Bone morphogenetic protein Cyclin-dependent kinase 1 Epidermal growth factor receptor Fibroblast growth factor receptor 1 Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 Insulin-like growth factor I receptor Macrophage colony-stimulating factor 1 receptor Macrophage-stimulating protein receptor Mast/stem cell growth factor receptor Kit Oxytocin receptor POsterior Segregation family member (pos-1) Platelet-derived growth factor receptor Platelet-derived growth factor receptor beta Proto-oncogene tyrosine-protein kinase Src Proto-oncogene tyrosine-protein kinase receptor Ret RecName: Full=Zinc finger protein mex-5 Receptor tyrosine-protein kinase erbB-2 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase ZAP-70 Tyrosine-protein kinase receptor FLT3 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2) Vasopressin V1a receptor	0	75	0	6	0	0	0	0	(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one CHEMBL276711 SU5146 SU5416 Semaxanib US10189853, semaxanib US9422297, SU5416 cid_5329098
BDBM50002173	5-hydroxytryptamine receptor 1A (5-HT1A) 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2C Adrenergic alpha1B Adrenergic receptor alpha Alpha-1A adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor and beta-3 adrenergic receptor D(1A) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor DOPAMINE Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor Dopamine D5 receptor Dopamine receptors; D2 & D4 Histamine H1 receptor Serotonin (5-HT) receptor Serotonin receptor (2b and 2c)	27	4	0	1	0	0	0	0	3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol 3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol 3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol CHEMBL431367 roxindole
BDBM50009073	Adenosine receptor A1 Adrenergic receptor alpha-1 Adrenergic receptor alpha-2 Adrenergic receptor beta Bile salt export pump CYSLTR2 Cysteinyl leukotriene receptor Cysteinyl leukotriene receptor 1 Cytochrome P450 2C9 D(2) dopamine receptor Histamine H1 receptor LTB4R Leukotriene 2 Mu-type opioid receptor Multidrug and toxin extrusion protein 1 Multidrug and toxin extrusion protein 2 Muscarinic acetylcholine receptor Nuclear receptor subfamily 1 group I member 2 Platelet activating factor receptor Pregnane X receptor (PXR) Serotonin 2 (5-HT2) receptor Solute carrier family 22 member 2 cPLA2 C2 streptokinase A precursor	16	23	0	6	0	0	0	0	4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide CHEMBL603 ZAFIRLUKAST cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate cyclopentyl 3-[2-methoxy-4-(2-methylphenylsulfonylcarbamoyl)benzyl]-1-methyl-1H-indol-5-ylcarbamate
BDBM50025206	5-hydroxytryptamine receptor 1A (5-HT1A) 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2C Adrenergic alpha1B Adrenergic receptor alpha Alpha-1A adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor and beta-3 adrenergic receptor D(1A) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor DOPAMINE DRD2 Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor Dopamine D5 receptor Dopamine receptor Dopamine receptors; D2 & D4 Histamine H1 receptor Serotonin receptor (2b and 2c)	31	0	1	0	0	0	0	0	(6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium TL99
BDBM50028091	ADRB2 Alpha-1A adrenergic receptor Cytochrome P450 1A2 Cytochrome P450 2C9 Cytochrome P450 2D6 (2D6) DOPAMINE Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor Dopamine Transporter (DAT) HTR2C Histamine H1 receptor Monoamine transporters; serotonin & dopamine Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M2 Norepinephrine Monoamine transporters Norepinephrine transporter Potassium voltage-gated channel subfamily H member 2 Serotonin (5-HT) receptor Serotonin receptor 2a and 2c (5HT2A and 5HT2C) Sigma non-opioid intracellular receptor 1 Sodium channel protein type 5 subunit alpha Sodium-dependent noradrenaline transporter Sodium-dependent serotonin transporter Voltage-dependent L-type calcium channel subunit alpha-1C adrenergic Alpha2	53	7	0	0	0	0	0	0	(1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime CHEMBL814 FLUVOXAMINE
BDBM50053173	Beta-lactamase Beta-lactamase (SHV-1) Beta-lactamase (TEM-1) Beta-lactamase ACC-4 Beta-lactamase AmpC Beta-lactamase BRO-1 Beta-lactamase GES-13 Beta-lactamase L1 Beta-lactamase SCO-1 Beta-lactamase TEM Beta-lactamase TEM-125 Beta-lactamase type II Carbapenem-hydrolizing beta-lactamase SFC-1 Carbepenem-hydrolyzing beta-lactamase KPC Class A carbapenemase KPC-2 Class D β-lactamase (OXA-1) Class D beta-lactamase Extended-spectrum beta-lactamase CTX-M-53 Gil1 IMI-1 PER-2 beta-lactamase PenB class A beta-lactamase SHV-1 beta-lactamase beta-Lactamase	3	79	0	0	0	0	0	0	(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda 6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide 3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid CHEMBL404 CL-298741 TAZOBACTAM US9120808, Tazobactam sodium salt US9676777, TAZ YTR-830H Zosyn
BDBM50069447	5-hydroxytryptamine receptor 1A (5-HT1A) 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2C ADRB2 Alpha-1A adrenergic receptor Alpha-2A adrenergic receptor Bile salt export pump Bile salt export pump (BSEP) Cytochrome P450 3A D(2) dopamine receptor DOPAMINE Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor Dopamine Transporter (DAT) Histamine H1 receptor Monoamine transporters; serotonin & dopamine Muscarinic acetylcholine receptor M2 Norepinephrine Monoamine transporters Norepinephrine transporter P-glycoprotein 1 Serotonin (5-HT) receptor Serotonin receptor 2a and 2c (5HT2A and 5HT2C) Sodium-dependent noradrenaline transporter Sodium-dependent serotonin transporter adrenergic Alpha2	41	10	3	0	0	0	0	0	1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one CHEMBL623 NEFAZODONE US9138393, Nefazodone HCl US9144538, Nefazodone HCl
BDBM50121975	1,3-beta-glucan synthase component GLS2 Adrenergic Alpha Bile salt export pump Butyrylcholinesterase (BuChE) Calcium channel Calcium channel (Type L) Cytochrome P450 2D1 Cytochrome P450 2D18 Cytochrome P450 2D2 Cytochrome P450 2D3 Cytochrome P450 2D6 Cytochrome P450 2D6 (2D6) Histidine-rich protein Multidrug and toxin extrusion protein 1 P-glycoprotein 1 Potassium voltage-gated channel subfamily D member 2 Potassium voltage-gated channel subfamily H member 2 Sodium channel protein type I I alpha subunit Uridine-5'-diphosphoglucuronosyltransferase 1A1 Uridine-5'-diphosphoglucuronosyltransferase 1A4 Uridine-5'-diphosphoglucuronosyltransferase 1A6 Uridine-5'-diphosphoglucuronosyltransferase 2B10 Uridine-5'-diphosphoglucuronosyltransferase 2B7 Voltage-dependent L-type calcium channel subunit alpha-1C	4	49	0	0	0	0	0	0	(6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol CARDIOQUIN CHEMBL1294 CIN-QUIN DURAQUIN QUINACT QUINAGLUTE QUINALAN QUINATIME QUINIDEX QUINIDINE QUINORA US9402878, Quinidine
BDBM50158460	Aldo-keto reductase family 1 member C1 Bile salt export pump Cytochrome P450 1A Cytochrome P450 2C19 Cytochrome P450 2C9 Cytochrome P450 2D6 (2D6) Cytochrome P450 2J2 Cytochrome P450 3A Eyes absent homolog 3 (EYA3) Eyes absent homolog 3 (EYA3) (ED) Monocarboxylate transporter 1 (MCT1) Monocarboxylate transporter 2 Multidrug resistance protein 1/Multidrug resistance associated protein 1 PA/PB1 Protein-tyrosine phosphatase 1B (PTP1B) Solute carrier family 22 member 12 Sphingosine 1-phosphate receptor 1 Zinc aminopeptidase leucine aminopeptidase nuclear receptor corepressor 2 isoform 2 perilipin-1 perilipin-5 photoreceptor-specific nuclear receptor streptokinase A precursor	4	26	1	4	0	0	0	0	(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone Benzbromarone CHEMBL388590 US9725430, Compound 1 Uroleap (TN) cid_2333
BDBM50192858	Aurora kinase A Aurora kinase B Casein kinase II alpha Cyclin-Dependent Kinase 2 (CDK2) Cyclin-Dependent Kinase 4 (CDK4) Ephrin receptor Epidermal growth factor receptor Focal adhesion kinase 1 Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 Hepatocyte growth factor receptor Insulin receptor Insulin-like growth factor I receptor Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase kinase kinase 8 NUAK family SNF1-like kinase 1 Platelet-derived growth factor receptor beta Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase AKT1 RAF serine/threonine protein kinase Receptor tyrosine-protein kinase erbB-2 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Tyrosine-protein kinase receptor FLT3 Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	25	0	0	0	0	0	0	CHEMBL3358966
BDBM50267508	5-Hydroxytryptamine receptor 6 (5-HT6) 5-Hydroxytryptamine receptor 7 (5-HT7) 5-hydroxytryptamine receptor 1A (5-HT1A) 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 3A Adrenergic alpha1B Alpha-1A adrenergic receptor Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Beta-3 adrenergic receptor D(1A) dopamine receptor D(2) dopamine receptor Dopamine D5 receptor Dopamine receptors; D2 & D4 Histamine H1 receptor Histamine H2 Receptor Histamine receptor (H3) Monoamine transporters; serotonin & dopamine Mu-type opioid receptor Serotonin (5-HT) receptor Serotonin receptor (2b and 2c) Sodium-dependent serotonin transporter	26	0	0	0	0	0	0	0	4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fluorophenylethyl)-piperidine CHEMBL516088
BDBM50300026	Aurora kinase B Cyclin-dependent kinase 2 Epidermal growth factor receptor Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 Hepatocyte growth factor receptor Insulin-like growth factor I receptor Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase 1 Platelet-derived growth factor receptor Platelet-derived growth factor receptor beta Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase Src Proto-oncogene tyrosine-protein kinase receptor Ret RAC-alpha serine/threonine-protein kinase AKT1 RAF proto-oncogene serine/threonine-protein kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-4 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase Lck Tyrosine-protein kinase receptor FLT3 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	24	0	0	0	0	0	0	(S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)-7-(2-methoxyethoxy)quinazolin-6-yl]pyrrolidine-2-carboxamide CHEMBL571040
BDBM50300027	Aurora kinase B Cyclin-dependent kinase 2 Epidermal growth factor receptor Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 2 Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 Hepatocyte growth factor receptor Insulin-like growth factor I receptor Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase 1 Platelet-derived growth factor receptor Platelet-derived growth factor receptor beta Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase Src Proto-oncogene tyrosine-protein kinase receptor Ret RAC-alpha serine/threonine-protein kinase AKT1 RAF proto-oncogene serine/threonine-protein kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-4 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase Lck Tyrosine-protein kinase receptor FLT3 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	24	0	0	0	0	0	0	(S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylamino)-7-(2-methoxyethoxy)quinazolin-6-yl]pyrrolidine-2-carboxamide CHEMBL569880
BDBM50314051	3-phosphoinositide dependent protein kinase-1 Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Inhibitor of NF-kappa-B kinase (IKK) Insulin-like growth factor I receptor MAP kinase-activated protein kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 2 Mitogen-activated protein kinase kinase kinase 8 PKC alpha and beta-2 Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase AKT1 RAF serine/threonine protein kinase Rho-associated protein kinase 1 SRC Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase PLK1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase Lck c-Jun N-terminal kinase, JNK	0	25	0	0	0	0	0	0	CHEMBL1089082 N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide
BDBM50316252	Aurora kinase B Casein kinase I Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Hepatocyte growth factor receptor Inhibitor of NF-kappa-B kinase (IKK) MAP kinase-activated protein kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 2 Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Platelet-derived growth factor receptor Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase Src Rho-associated protein kinase 1 Ribosomal protein S6 kinase alpha 1 SRC Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase Lyn Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	25	0	0	0	0	0	0	CHEMBL1095626 methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
BDBM50316253	Aurora kinase B Casein kinase I Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Hepatocyte growth factor receptor Inhibitor of NF-kappa-B kinase (IKK) MAP kinase-activated protein kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 2 Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Platelet-derived growth factor receptor Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase Src Rho-associated protein kinase 1 Ribosomal protein S6 kinase alpha 1 SRC Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase Lyn Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	25	0	0	0	0	0	0	CHEMBL1095627 tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
BDBM50329198	Aurora kinase B CaM kinase IV Casein kinase I isoform delta Cyclin-dependent kinase 2 Ephrin type-B receptor 4 (EphB4) Epidermal growth factor receptor Hepatocyte growth factor receptor Inhibitor of NF-kappa-B kinase (IKK) Insulin-like growth factor I receptor Interleukin-1 receptor-associated kinase 4 Mitogen-activated protein kinase 1 Protein kinase C alpha type RAC-alpha serine/threonine-protein kinase AKT1 Rho-associated protein kinase 2 Ribosomal protein S6 kinase alpha-3 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase MST2 Serine/threonine-protein kinase Nek2 Serine/threonine-protein kinase PLK3 Testis-specific serine/threonine-protein kinase 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase receptor FLT3 Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	27	0	0	0	0	0	0	2-(ethyl((5-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino)isothiazol-3-yl)methyl)amino)-2-methylpropan-1-ol 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol CHEMBL1232515 CHEMBL1650533
BDBM50331629	Cytochrome P450 1A Cytochrome P450 2C19 Cytochrome P450 2C9 Cytochrome P450 2D6 (2D6) Cytochrome P450 3A Diacylglycerol O-acyltransferase 1 (DGAT1) Fibroblast growth factor receptor 1 Insulin-like growth factor I receptor MAP kinase-activated protein kinase 2 Mitogen-activated protein kinase 14 Non-receptor tyrosine-protein kinase TYK2 PKC alpha and beta-2 Potassium voltage-gated channel subfamily H member 2 Protein kinase C (PKC) Protein kinase C alpha type Protein kinase C delta type Serine/threonine-protein kinase PLK1 Signal transducer and activator of transcription 3 Tyrosine-protein kinase BTK Tyrosine-protein kinase ITK/TSK Tyrosine-protein kinase JAK3 Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	24	0	0	0	0	0	0	5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl)-1H-pyrazole-4-carboxamide CHEMBL1290746
BDBM50335188	Aurora kinase B CaM kinase IV Casein kinase I isoform delta Cyclin-dependent kinase 2 Ephrin type-B receptor 4 (EphB4) Epidermal growth factor receptor Hepatocyte growth factor receptor Inhibitor of NF-kappa-B kinase (IKK) Insulin-like growth factor I receptor Interleukin-1 receptor-associated kinase 4 Mitogen-activated protein kinase 1 Protein kinase C alpha type RAC-alpha serine/threonine-protein kinase AKT1 Rho-associated protein kinase 2 Ribosomal protein S6 kinase alpha-3 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase MST2 Serine/threonine-protein kinase Nek2 Serine/threonine-protein kinase PLK3 Testis-specific serine/threonine-protein kinase 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase receptor FLT3 Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)	0	48	0	0	0	0	0	0	CHEMBL1650545 CHEMBL1650551 N-[3-[(3,3-Difluoro-1-pyrrolidinyl)methyl]-5-isothiazolyl]-6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine Hydrochloride
BDBM50384721	ALK tyrosine kinase receptor Cytoplasmic tyrosine-protein kinase BMX Ephrin type-A receptor 3 Ephrin type-B receptor 2 Fibroblast growth factor receptor High affinity nerve growth factor receptor Insulin receptor Insulin-like growth factor 1 receptor JNK1/JNK2 Macrophage colony-stimulating factor 1 receptor (c-Fms) Macrophage-stimulating protein receptor Mast/stem cell growth factor receptor Kit NT-3 growth factor receptor Neuronal proto-oncogene tyrosine-protein kinase Src Platelet-derived growth factor receptor beta Proto-oncogene tyrosine-protein kinase ROS Proto-oncogene tyrosine-protein kinase receptor Ret Receptor-type tyrosine-protein kinase FLT3 TPR/MET fusion protein Tyrosine-protein kinase Fgr Tyrosine-protein kinase Lyn Tyrosine-protein kinase ZAP-70 Tyrosine-protein kinase receptor Tie-1 Vascular endothelial growth factor receptor 1	0	25	0	0	0	0	0	0	CHEMBL2037224
BDBM50384725	ALK tyrosine kinase receptor BDNF/NT-3 growth factors receptor Cytoplasmic tyrosine-protein kinase BMX Ephrin type-A receptor 3 Ephrin type-B receptor 2 Fibroblast growth factor receptor High affinity nerve growth factor receptor Insulin receptor Insulin-like growth factor 1 receptor JNK1/JNK2 Macrophage colony-stimulating factor 1 receptor (c-Fms) Macrophage-stimulating protein receptor Mast/stem cell growth factor receptor Kit Neuronal proto-oncogene tyrosine-protein kinase Src Platelet-derived growth factor receptor beta Proto-oncogene tyrosine-protein kinase ROS Proto-oncogene tyrosine-protein kinase receptor Ret Receptor-type tyrosine-protein kinase FLT3 TPR/MET fusion protein Tyrosine-protein kinase Fgr Tyrosine-protein kinase Lyn Tyrosine-protein kinase ZAP-70 Tyrosine-protein kinase receptor Tie-1 Vascular endothelial growth factor receptor 1	0	25	0	0	0	0	0	0	CHEMBL2037209
BDBM50384726	ALK tyrosine kinase receptor Cytoplasmic tyrosine-protein kinase BMX Ephrin type-A receptor 3 Ephrin type-B receptor 2 Fibroblast growth factor receptor High affinity nerve growth factor receptor Insulin receptor Insulin-like growth factor 1 receptor JNK1/JNK2 Macrophage colony-stimulating factor 1 receptor (c-Fms) Macrophage-stimulating protein receptor Mast/stem cell growth factor receptor Kit NT-3 growth factor receptor Neuronal proto-oncogene tyrosine-protein kinase Src Platelet-derived growth factor receptor beta Proto-oncogene tyrosine-protein kinase ROS Proto-oncogene tyrosine-protein kinase receptor Ret Receptor-type tyrosine-protein kinase FLT3 TPR/MET fusion protein Tyrosine-protein kinase Fgr Tyrosine-protein kinase Lyn Tyrosine-protein kinase ZAP-70 Tyrosine-protein kinase receptor Tie-1 Vascular endothelial growth factor receptor 1	0	25	0	0	0	0	0	0	CHEMBL2037208
BDBM50384727	ALK tyrosine kinase receptor BDNF/NT-3 growth factors receptor Cytoplasmic tyrosine-protein kinase BMX Ephrin type-A receptor 3 Ephrin type-B receptor 2 Fibroblast growth factor receptor High affinity nerve growth factor receptor Insulin receptor Insulin-like growth factor 1 receptor JNK1/JNK2 Macrophage colony-stimulating factor 1 receptor (c-Fms) Macrophage-stimulating protein receptor Mast/stem cell growth factor receptor Kit Neuronal proto-oncogene tyrosine-protein kinase Src Platelet-derived growth factor receptor beta Proto-oncogene tyrosine-protein kinase ROS Proto-oncogene tyrosine-protein kinase receptor Ret Receptor-type tyrosine-protein kinase FLT3 TPR/MET fusion protein Tyrosine-protein kinase Fgr Tyrosine-protein kinase Lyn Tyrosine-protein kinase ZAP-70 Tyrosine-protein kinase receptor Tie-1 Vascular endothelial growth factor receptor 1	0	26	0	0	0	0	0	0	CHEMBL2037226
BDBM81780	5-Hydroxytryptamine receptor 6 (5-HT6) 5-hydroxytryptamine receptor 1A (5-HT1A) Alpha-1A adrenergic receptor Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor CHRM5 D(1A) dopamine receptor DOPAMINE Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor Dopamine receptor HTR1D HTR2C Histamine H1 receptor Monoamine transporters; serotonin & dopamine Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor M3 Muscarinic acetylcholine receptor M4 Serotonin (5-HT) receptor Serotonin 1B/1D receptor Serotonin receptor 2a and 2c (5HT2A and 5HT2C) Sodium-dependent noradrenaline transporter Voltage-gated sodium channel subunit alpha Nav1.8 adrenergic Alpha2	27	0	0	0	0	0	0	0	CAS_6438382 NSC_6438382 SR 46349B
BDBM82517	5-HT3A Serotonin Receptor 5-Hydroxytryptamine receptor 7 (5-HT7) 5-hydroxytryptamine receptor 1A (5-HT1A) Adrenergic alpha1B Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor Alpha-1A adrenergic receptor Alpha-1D adrenergic receptor D(1A) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor DRD2 DRD3 Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor HTR1A HTR1B HTR1D HTR2A HTR2C HTR3A Serotonin (5-HT) receptor Serotonin 1 (5-HT1) receptor Serotonin 1B/1D receptor Serotonin receptor 2a and 2c (5HT2A and 5HT2C) adrenergic Alpha1	61	0	0	0	0	0	0	0	2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione CAS_107966 CHEMBL126632 CHEMBL8618 NAN-190 NSC_107966
BDBM84342	5-Hydroxytryptamine receptor 7 (5-HT7) ADRA1A ADRA1B ADRA2A Alpha adrenergic receptor 1A and 1B Alpha-1A adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor and beta-3 adrenergic receptor Beta-3 adrenergic receptor Beta-adrenergic receptor kinase 1 Cerebral cortex alpha adrenergic receptor DRD1 DRD2 Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor Norepinephrine transporter Serotonin (5-HT) receptor Sodium-dependent noradrenaline transporter Steroidogenic Factor 1 adrenergic Alpha1 adrenergic Alpha2 nuclear receptor subfamily 0 group B member 1	42	2	1	0	0	0	0	0	4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride 4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride 4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride DL-ADRENALINE HYDROCHLORIDE EPINEPHRINE EPINEPHRINE,(+) MLS001333244 SMR000058236 cid_5924