Compound Name (alphabetical) | Binding Targets | Enz. Inhib. Data | ITC Data | Alternate Compound Names |
---|
Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
---|
BDBM11639
| - β-Carbonic anhydrase 2 (CA 2)
- 3-phosphoinositide dependent protein kinase-1
- Alpha carbonic anhydrase
- Arachidonate 5-lipoxygenase
- Astrosclerin-3
- COX-1
- COX-2
- Carbonate dehydratase
- Carbonic Anhydrase (mtCA 1)
- Carbonic Anhydrase (mtCA 3)
- Carbonic Anhydrase 2 (Can2)
- Carbonic Anhydrase III
- Carbonic Anhydrase IV
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIV
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 13 (CA XIII)
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Carbonic anhydrase, alpha family
- Carbonic anhydrases; II & IX
- Cruzipain
- Cyclooxygenase
- Cyclooxygenase-1
- Cyclooxygenase-1 (COX-1)
- Cyclooxygenase-2
- Cyclooxygenase-2 (COX-2)
- Cytochrome P450 2C9
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 2
- Delta carbonic anhydrase
- Epoxide hydratase
- GTP-binding protein (rab7)
- Gamma-carbonic anhydrase
- Mitogen-activated protein kinase 14
- PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE)
- Prostaglandin E synthase
- Prostaglandin E synthase/G/H synthase 2
- Prostaglandin G/H synthase (Cyclooxygenase-2)
- Prostaglandin G/H synthase (cyclooxygenase)
- Quinolone resistance protein norA
- Ras-related C3 botulinum toxin substrate 1
- Ras-related protein Rab-2A.
- beta-Carbonic Anhydrase
- cGMP-specific 3',5'-cyclic phosphodiesterase
- cell division cycle 42 (GTP binding protein, 25kDa)
- ras protein
| 126 | 404 | 1 | 8 | 0 | 0 | 0 | 0 | - 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide
- CHEMBL118
- CLX
- Celebrex
- Celecoxib
- US8741944, Comparative Compound
- US9388139, Celecoxib
- cid_2662
|
BDBM15236
| - 1-deoxy-D-xylulose 5-phosphate reductoisomerase
- 17-beta-hydroxysteroid dehydrogenase type 3
- 3-oxoacyl-acyl-carrier protein reductase
- Acetylcholinesterase
- Acid phosphatase (acpA)
- Aldo-keto reductase family 1 member C21
- Aldose reductase (AR)
- Alkaline phosphatase placental-like
- Alkaline phosphatase, tissue-nonspecific isozyme
- Alpi
- Amyloid β-protein (Aβ42)
- Arginase
- Aromatase (CYP19)
- Aurora kinase B
- Beta amyloid A4 protein
- Cell division protein kinase 5
- Cholinesterase
- Cytochrome P450 1A1
- Cytochrome P450 1B1
- DNA Gyrase
- DNA dC->dU-editing enzyme APOBEC-3G
- DNA primase traC
- Death-associated protein kinase 1
- ELAV-like protein 3
- Enoyl-acyl-carrier protein reductase
- Fatty acid synthase
- G-protein coupled receptor 35
- Glyoxalase 1 (GLO1)
- Histone Lysine Demethylase
- Homo sapiens huntingtin (HTT), mRNA
- Human immunodeficiency virus type 1 integrase
- Insulin receptor
- Intestinal alkaline phosphatase
- Lymphocyte differentiation antigen CD38
- Matrix metalloproteinase-1 (cd-MMP-1)
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 14
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Multidrug resistance-associated protein 2 (MRP2)
- Myosin light chain kinase, smooth muscle
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- Protein E6
- Protein kinase Pfmrk
- Serine/threonine-protein kinase 33
- Serine/threonine-protein kinase PIM
- Sialidase 2
- Tau
- Trypsin
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase receptor FLT3
- Tyrosine-protein kinase transforming protein FPS
- Xanthine dehydrogenase/oxidase
- alpha-Amylase
- lens epithelium-derived growth factor p75
- probable DNA dC->dU-editing enzyme APOBEC-3A
| 11 | 51 | 1 | 7 | 0 | 0 | 0 | 0 | - 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
- 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
- CHEMBL164
- Cannabiscetin
- Myricetin
- Myricetin (20)
- Myricetin (Myr)
- cid_5281672
|
BDBM50002338
| - 5-HT1
- 5-Hydroxytryptamine receptor 6 (5-HT6)
- 5-Hydroxytryptamine receptor 7 (5-HT7)
- 5-hydroxytryptamine receptor 1A (5-HT1A)
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- ADRA1A
- ADRA1B
- ADRA2C
- ADRB2
- Adenosine receptor A1
- Adrenergic receptor alpha-2
- Adrenergic receptor beta
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Bile salt export pump
- CHRM5
- Calcium channel
- Calcium channel (Type L)
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- DOPAMINE
- DRD1
- DRD2
- Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
- Dopamine D5 receptor
- Dopamine receptor
- Dopamine receptors; D1 & D2
- Dopamine receptors; D2 & D4
- GABA receptor gamma-1 subunit
- GST-MALT lymphoma-associated translocation (MALT1)
- HTR6
- Histamine H1 receptor
- Muscarinic acetylcholine receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Pleiotropic ABC efflux transporter of multiple drugs
- Potassium voltage-gated channel subfamily H member 2
- Proteasome subunit alpha type-6
- Serotonin (5-HT) receptor
- Serotonin 1 (5-HT1) receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Serum albumin
- Sigma non-opioid intracellular receptor 1
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type I I alpha subunit
- Voltage-dependent L-type calcium channel subunit alpha-1C
- adrenergic Alpha2
| 122 | 41 | 1 | 1 | 0 | 0 | 0 | 0 | - (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine
- 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine
- 10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine
- 10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)
- CHEMBL479
- MELLARIL
- MELLARIL-S
- THIORIDAZINE
- TP-21
- US9504692, Thioridazine
|
BDBM50156383
| - 3-phosphoinositide dependent protein kinase-1
- ALK tyrosine kinase receptor
- Activin receptor type-1
- Aurora kinase A
- Cyclin-Dependent Kinase 4 (CDK4)
- Cyclin-dependent kinase 2
- Ephrin receptor
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 4
- Glycogen synthase kinase-3 beta
- Hepatocyte growth factor receptor
- Insulin receptor
- Insulin-like growth factor I receptor
- MAP kinase-activated protein kinase 2
- MAP kinase-activated protein kinase 5
- MAP kinase-interacting serine/threonine-protein kinase 2
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase kinase kinase 8
- Non-receptor tyrosine-protein kinase TYK2
- Phosphatidylinositol 3-kinase catalytic subunit type 3
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- Phosphatidylinositol 4-kinase beta
- Platelet-derived growth factor receptor
- Protein kinase C alpha type
- Protein kinase C theta type
- Protein kinase N1
- Proto-oncogene tyrosine-protein kinase Src
- Proto-oncogene tyrosine-protein kinase receptor Ret
- RAC-alpha serine/threonine-protein kinase AKT1
- Receptor tyrosine-protein kinase erbB-2
- Receptor tyrosine-protein kinase erbB-4
- Rho-associated protein kinase 2
- Serine/threonine-protein kinase PLK1
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase CSK
- Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase ZAP-70
- Tyrosine-protein kinase receptor FLT3
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
- cAMP-dependent protein kinase (PKA)
| 0 | 62 | 0 | 0 | 0 | 0 | 0 | 0 | |
BDBM50182493
| - ALK tyrosine kinase receptor
- Aurora kinase A
- Cyclin-dependent kinase 2
- EPHB1
- Ephrin receptor
- Ephrin type-A receptor 1 (EPHA1)
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 4
- Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
- Glycogen synthase kinase-3 beta
- Hepatocyte growth factor receptor
- High affinity nerve growth factor receptor
- Insulin receptor
- Insulin-like growth factor I receptor
- Leukocyte tyrosine kinase receptor
- Macrophage-stimulating protein receptor
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 14
- Muscle, skeletal receptor tyrosine protein kinase
- Non-receptor tyrosine-protein kinase TYK2
- Platelet-derived growth factor receptor
- Platelet-derived growth factor receptor beta
- Protein kinase C (PKC)
- Protein kinase C alpha type
- Protein kinase N1
- Protein kinase N2
- Proto-oncogene tyrosine-protein kinase ROS
- Proto-oncogene tyrosine-protein kinase Src
- Proto-oncogene tyrosine-protein kinase receptor Ret
- RAC-alpha serine/threonine-protein kinase AKT1
- Receptor tyrosine-protein kinase erbB-2
- Receptor tyrosine-protein kinase erbB-4
- SRC
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase ABL2
- Tyrosine-protein kinase BRK
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase FER
- Tyrosine-protein kinase Fes/Fps
- Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase Yes
- Tyrosine-protein kinase receptor FLT3
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
- cAMP-dependent protein kinase (PKA)
| 0 | 61 | 0 | 0 | 0 | 0 | 0 | 0 | - CHEMBL3818247
- US9512121, 22
|
BDBM50334150
| - 15-Lipoxygenase (LoxA)
- 5-HT3A Serotonin Receptor
- 5-Hydroxytryptamine receptor 6 (5-HT6)
- 5-Hydroxytryptamine receptor 7 (5-HT7)
- 5-hydroxytryptamine receptor 1A (5-HT1A)
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Bile salt export pump
- Calcium channel
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2J2
- Cytochrome P450 3A
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- DOPAMINE
- DRD1
- DRD2
- Delta-type opioid receptor
- Dopamine D2 receptor
- Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
- Dopamine receptor
- Dopamine receptors; D2 & D4
- Glycine receptor subunit alpha-1
- HTR6
- Histamine H1 receptor
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Multidrug and toxin extrusion protein 1
- Multidrug and toxin extrusion protein 2
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- P-glycoprotein (P-gp)
- P-glycoprotein 1
- P-glycoprotein 1 and 3 (MDR1a/MDR1b)
- Potassium voltage-gated channel subfamily H member 2
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sigma non-opioid intracellular receptor 1
- Sodium channel protein type 7 subunit alpha
- Solute carrier family 22 member 2
- Twik-RElated Potassium (K+) channel 1 (TREK1)
- Ubiquitin carboxyl-terminal hydrolase 1
- Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48
- Voltage-gated L-type calcium channel
- Voltage-gated T-type calcium channel
| 81 | 42 | 1 | 2 | 0 | 0 | 0 | 0 | - 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
- 1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one
- 1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)
- 1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
- 1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)
- CHEMBL1423
- MCN-JR-6238
- N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine
- NCGC00015802
- Orap
- PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
- Pimozide
- R-6238
|