Found 32 hits for monomerid = 50422689 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glutathione reductase (GR)
(Homo sapiens (Human)) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
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| Article PubMed
| 1.04E+4 | n/a | 1.88E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ondokuz Mayis University
| Assay Description Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-... |
J Enzyme Inhib Med Chem 28: 824-9 (2013)
Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4 |
More data for this Ligand-Target Pair | |
Glutathione S-transferase (GST)
(Homo sapiens (Human)) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| 3.24E+4 | n/a | 5.64E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Ondokuz Mayis University
| Assay Description Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,... |
J Enzyme Inhib Med Chem 28: 824-9 (2013)
Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4 |
More data for this Ligand-Target Pair | |
Glutathione peroxidase 1 (GPx)
(Homo sapiens (Human)) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| 3.27E+4 | n/a | 4.43E+4 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Ondokuz Mayis University
| Assay Description Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ... |
J Enzyme Inhib Med Chem 28: 824-9 (2013)
Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4 |
More data for this Ligand-Target Pair | |
Solute carrier family 15 member 2
(Homo sapiens (Human)) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank Article PubMed
| 1.26E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano
Curated by ChEMBL
| Assay Description Binding affinity to human PepT2 in SKTP cells |
Bioorg Med Chem 19: 4544-51 (2011)
Article DOI: 10.1016/j.bmc.2011.06.027 BindingDB Entry DOI: 10.7270/Q2MP549P |
More data for this Ligand-Target Pair | |
Solute carrier family 15 member 2
(Homo sapiens (Human)) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank Article PubMed
| 1.26E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano
Curated by ChEMBL
| Assay Description Binding affinity to human PepT2 in SKTP cells |
Bioorg Med Chem 19: 4544-51 (2011)
Article DOI: 10.1016/j.bmc.2011.06.027 BindingDB Entry DOI: 10.7270/Q2MP549P |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| DrugBank Article PubMed
| 2.60E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells |
J Med Chem 48: 4410-9 (2005)
Article DOI: 10.1021/jm048982w BindingDB Entry DOI: 10.7270/Q2Q24116 |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 23.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 2.36 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 18.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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Similars
| MMDB Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 2.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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Similars
| MMDB Article PubMed
| n/a | n/a | 47.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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Similars
| MMDB Article PubMed
| n/a | n/a | 4.71 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 402 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 89.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 386 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 9.43 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
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DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 14.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 3.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| MMDB Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| MMDB Article PubMed
| n/a | n/a | 0.0940 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| MMDB Article PubMed
| n/a | n/a | 14.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 9.43 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 1.18 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 14.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 54.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| MMDB Article PubMed
| n/a | n/a | 7.07 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| MMDB Article PubMed
| n/a | n/a | 9.43 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 2B
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 6.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2B |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |
Penicillin-binding protein 1A
(Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50422689
(640/359 | CEFUROXIME)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 4.71 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP1A |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/aac.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this Ligand-Target Pair | |